Biocompatibility and Osteoconductivity of Hydroxyapatite/Polysaccharide Nanocomposite Microparticles

2006 ◽  
pp. 561-564
Author(s):  
H. Omi ◽  
Soichiro Itoh ◽  
Toshiyuki Ikoma ◽  
Y. Asou ◽  
S. Nishikawa ◽  
...  
Keyword(s):  
Nanocomposite Microparticles

Preparation of hybrid polymer nanocomposite microparticles by a nanoparticle stabilised dispersion polymerisation

2008 ◽  
Vol 18 (9) ◽  
pp. 998 ◽  
Author(s):  
Jixin Yang ◽  
Tom Hasell ◽  
Wenxin Wang ◽  
Jun Li ◽  
Paul D. Brown ◽  
...  
Keyword(s):  
Polymer Nanocomposite ◽  
Hybrid Polymer ◽  
Nanocomposite Microparticles

Biocompatibility and Osteoconductivity of Hydroxyapatite/Polysaccharide Nanocomposite Microparticles

2006 ◽  
Vol 309-311 ◽  
pp. 561-564 ◽  
Author(s):  
H. Omi ◽  
Soichiro Itoh ◽  
Toshiyuki Ikoma ◽  
Y. Asou ◽  
S. Nishikawa ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Bone Formation ◽  
Chondroitin Sulfate ◽  
Bone Defect ◽  
High Adsorption ◽  
Adsorption Ability ◽  
Nanocomposite Microparticles

Hydroxyapatite/hyaluronic acid (HAp/HyA) and hydroxyapatite/chondroitin sulfate (HAp/ChS) microparticles, which show the high adsorption ability of proteins, high biocompatibility and osteoconductivity, are potential scaffolds for a time-controlled BMP release. The present study evaluated the biocompatibility and osteoconductivity of the composites after injection into bone defect. Drilled bone holes were made at tibia and femur of Japanese white rabbits, and HAp/HyA or HAp/ChS was implanted into each bone hole using an injection syringe. After 2 and 4 weeks of implantation, rabbits were sacrificed and histological observations were conducted with HE, TRAP, and ALP staining. Histological observations revealed that HAp/ChS has superior biocompatibility compared with HAp/HyA, and 20% HAp/ChS promotes bone formation as well as osteoblast activities compared with lower ratios of HAp/ChS.

scholarly journals Synthesis of magnetic nanocomposite microparticles for binding of chlorinated organics in contaminated water sources

2020 ◽  
Vol 137 (37) ◽  
pp. 49109
Author(s):  
Angela M. Gutierrez ◽  
Rohit Bhandari ◽  
Jiaying Weng ◽  
Arnold Stromberg ◽  
Thomas D. Dziubla ◽  
...  
Keyword(s):  
Water Sources ◽  
Magnetic Nanocomposite ◽  
Contaminated Water ◽  
Chlorinated Organics ◽  
Nanocomposite Microparticles
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