Design of Integrated Control System for Microfluidic PCR Analysis Instrument

In this study, the design and development of an integrated control system for microfluidic PCR analysis instrument was presented. PID temperature control algorithm is used. The micro pumps, micro valves, and micro-mixers are command controlled by PC serial port to work together for samples and reagents driving. Sequential control strategy is introduced to control micro-pumps, micro valves, mixers, high-voltage module, and PCR reaction temperature. Labview as a software development platform is utilized to achieve human-computer exchange. All these designs are aimed to achieve the PCR reaction continuously on line from DNA extraction, purification, amplification to detection. An effective design idea for the coupling of complex microfluidic chip and instrument control was providing.