Monitoring Unfractionated Heparin: A Review of Activated Partial Thromboplastin Time Versus Antifactor Xa

2019 ◽  
Vol 30 (4) ◽  
pp. 305-312
Author(s):  
Christine R. Parker ◽  
Vivek Kataria
Keyword(s):  
Unfractionated Heparin ◽  
Partial Thromboplastin Time ◽  
Activated Partial Thromboplastin Time ◽  
Antifactor Xa

scholarly journals Evaluation of Antifactor-Xa Heparin Assay and Activated Partial Thromboplastin Time Values in Patients on Therapeutic Continuous Infusion Unfractionated Heparin Therapy

2019 ◽  
Vol 25 ◽  
pp. 107602961987603 ◽  
Author(s):  
Kevin McLaughlin ◽  
Jessica Rimsans ◽  
Katelyn W. Sylvester ◽  
John Fanikos ◽  
David M. Dorfman ◽  
...  
Keyword(s):  
Unfractionated Heparin ◽  
Continuous Infusion ◽  
Partial Thromboplastin Time ◽  
Clinical Management ◽  
Laboratory Tests ◽  
Heparin Therapy ◽  
Activated Partial Thromboplastin Time ◽  
Coagulation Test ◽  
New Correlation ◽  
Antifactor Xa

Clinical uncertainty exists regarding which assay should be designated as the standard monitoring coagulation test for intravenous unfractionated heparin (UFH). Several studies have compared the use of activated partial thromboplastin time (aPTT) and antifactor-Xa (anti-Xa) and have come out with varying results. The correlation between these 2 tests varied, markedly from strong to weak. Some have demonstrated that monitoring with anti-Xa heparin assay leads to fewer dose adjustments, resulting in fewer laboratory tests, while others have not. In the current study, we evaluated the correlation between aPTT and anti-Xa values to guide clinical management of UFH, with the intention to develop a new correlation nomogram.

scholarly journals Monitoring of Unfractionated Heparin Using Activated Partial Thromboplastin Time

2013 ◽  
Vol 20 (7) ◽  
pp. 723-728 ◽  
Author(s):  
Je Sang Kim ◽  
Hyun Jong Lee ◽  
Ji Dong Sung ◽  
Hee-Jin Kim ◽  
Soo-Youn Lee ◽  
...  
Keyword(s):  
Unfractionated Heparin ◽  
Partial Thromboplastin Time ◽  
Activated Partial Thromboplastin Time
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