The Expanding Role of the HMG-CoA Reductase Inhibitor, The Most Widely Prescribed Drug in the World

American Journal of Critical Care ◽

10.4037/ajcc2005.14.6.555 ◽

2005 ◽

Vol 14 (6) ◽

pp. 555-558 ◽

Author(s):

Laurie G. Futterman ◽

Louis Lemberg

Keyword(s):

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

The World ◽

Hmg Coa Reductase Inhibitor ◽

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Molecular rationale delineating the role of lycopene as a potent HMG-CoA reductase inhibitor: in vitro and in silico study

Natural Product Research ◽

10.1080/14786419.2015.1108977 ◽

2015 ◽

Vol 30 (18) ◽

pp. 2111-2114 ◽

Author(s):

Sahir Sultan Alvi ◽

Danish Iqbal ◽

Saheem Ahmad ◽

M. Salman Khan

Keyword(s):

In Silico ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

In Silico Study ◽

Hmg Coa Reductase Inhibitor ◽

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A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid

British Journal of Pharmacology ◽

10.1038/sj.bjp.0704070 ◽

2001 ◽

Vol 133 (3) ◽

pp. 406-412 ◽

Author(s):

Timothy J Stalker ◽

Allan M Lefer ◽

Rosario Scalia

Keyword(s):

Reductase Inhibitor ◽

Mevalonic Acid ◽

Microvascular Endothelium ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

Anti Inflammatory ◽

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Role of tyrosine phosphorylation of phospholipase C γ1 in the signaling pathway of HMG-CoA reductase inhibitor-induced cell death of L6 myoblasts

FEBS Letters ◽

10.1016/s0014-5793(99)00188-x ◽

1999 ◽

Vol 446 (1) ◽

pp. 91-94 ◽

Author(s):

Tatsuro Mutoh ◽

Takanori Kumano ◽

Hiroto Nakagawa ◽

Masaru Kuriyama

Keyword(s):

Phospholipase C ◽

Signaling Pathway ◽

Tyrosine Phosphorylation ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Role of Cardiac ATP-Sensitive K+ Channels Induced by HMG CoA Reductase Inhibitor in Ischemic Rabbit Hearts.

Hypertension Research ◽

10.1291/hypres.24.573 ◽

2001 ◽

Vol 24 (5) ◽

pp. 573-577 ◽

Author(s):

Hitoshi KAWABATA ◽

Teruhiko RYOMOTO ◽

Kinji ISHIKAWA

Keyword(s):

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells

Oncology Reports ◽

10.3892/or.11.5.1053 ◽

2004 ◽

Author(s):

Takemi Otsuki ◽

Haruko Sakaguchi ◽

Tamayo Hatayama ◽

Tomohiro Fujii ◽

Takayuki Tsujioka ◽

...

Keyword(s):

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Myeloma Cells ◽

Hmg Coa Reductase Inhibitor ◽

Coa Reductase ◽

Human Myeloma Cells

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HMG-COA REDUCTASE INHIBITOR AFFECTS BLOOD PRESSURE AND VASCULAR REACTIVITY

Clinical and Experimental Pharmacology and Physiology ◽

10.1111/j.1440-1681.1995.tb02934.x ◽

1995 ◽

Vol 22 (s1) ◽

pp. S316-S317 ◽

Author(s):

N. Li ◽

M. Sawamura ◽

Y. Nara ◽

K. Kizawa ◽

K. Ikeda ◽

...

Keyword(s):

Blood Pressure ◽

Reductase Inhibitor ◽

Vascular Reactivity ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Combined treatment of angiotensin receptor blocker and HMG-CoA reductase inhibitor synergistically improves cardiac dysfunction in Dahl rats

Journal of Molecular and Cellular Cardiology ◽

10.1016/j.yjmcc.2007.07.050 ◽

2008 ◽

Vol 44 (2) ◽

pp. 446-447

Author(s):

Yasuhiro Maejima ◽

Susumu Adachi ◽

Kazuya Isobe ◽

Hiroshi Ito ◽

Mitsuaki Isobe

Keyword(s):

Cardiac Dysfunction ◽

Reductase Inhibitor ◽

Angiotensin Receptor Blocker ◽

Combined Treatment ◽

Receptor Blocker ◽

Angiotensin Receptor ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, of patients with heterozygous familial hypercholesterolemia

Atherosclerosis ◽

10.1016/s0021-9150(01)00765-1 ◽

2002 ◽

Vol 163 (1) ◽

pp. 157-164 ◽

Author(s):

Yoshihiro Noji ◽

Toshinori Higashikata ◽

Akihiro Inazu ◽

Atsushi Nohara ◽

Kosei Ueda ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Reductase Inhibitor ◽

Term Treatment ◽

Hmg Coa Reductase ◽

Heterozygous Familial Hypercholesterolemia ◽

Long Term Treatment ◽

Hmg Coa Reductase Inhibitor ◽

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Treatment of hypercholesterolemia with the HMG CoA reductase inhibitor, simvastatin

Cardiovascular Drugs and Therapy ◽

10.1007/bf01883868 ◽

1989 ◽

Vol 3 (2) ◽

pp. 219-227 ◽

Author(s):

GMB Berger ◽

AD Marais ◽

HC Seftel ◽

SG Baker ◽

D Mendelsohn ◽

...

Keyword(s):

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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The HMG-CoA reductase inhibitor, atorvastatin, attenuates the effects of acute administration of amyloid-β1–42 in the rat hippocampus in vivo

Neuropharmacology ◽

10.1016/j.neuropharm.2006.07.031 ◽

2007 ◽

Vol 52 (1) ◽

pp. 136-145 ◽

Author(s):

Rachael M. Clarke ◽

Florence O'Connell ◽

Anthony Lyons ◽

Marina A. Lynch

Keyword(s):

Reductase Inhibitor ◽

Rat Hippocampus ◽

Acute Administration ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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