scholarly journals Grafting Using Injectable Calcium Sulfate in Bone Tumor Surgery: Comparison with Demineralized Bone Matrix-based Grafting

2011 ◽  
Vol 3 (3) ◽  
pp. 191 ◽  
Author(s):  
June Hyuk Kim ◽  
Joo Han Oh ◽  
Ilkyu Han ◽  
Han-Soo Kim ◽  
Seok Won Chung
Keyword(s):  
Bone Tumor ◽  
Calcium Sulfate ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Tumor Surgery ◽  
Demineralized Bone

scholarly journals Preparation and Characterization of Moldable Demineralized Bone Matrix/Calcium Sulfate Composite Bone Graft Materials

2021 ◽  
Vol 12 (4) ◽  
pp. 56
Author(s):  
I-Cheng Chen ◽  
Chen-Ying Su ◽  
Chun-Cheih Lai ◽  
Yi-Syue Tsou ◽  
Yudong Zheng ◽  
...  
Keyword(s):  
Bone Graft ◽  
Calcium Sulfate ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Washout Rate ◽  
Graft Material ◽  
Noncollagenous Proteins ◽  
Freeze Dried ◽  
Demineralized Bone ◽  
Composite Bone

Demineralized bone matrix (DBM) is a decalcified allo/xenograft retaining collagen and noncollagenous proteins, which has been extensively used because of its osteoconductive and osteoinductive properties. Calcium sulfate (CaSO4, CS) is a synthetic bone substitute used in bone healing with biocompatible, nontoxic, bioabsorbable, osteoconductive, and good mechanical characteristics. This study aims to prepare a DBM/CS composite bone graft material in a moldable putty form without compromising the peculiar properties of DBM and CS. For this purpose, firstly, porcine femur was defatted using chloroform/methanol and extracted by acid for demineralization, then freeze-dried and milled/sieved to obtain DBM powder. Secondly, the α-form and β-form of calcium sulfate hemihydrate (CaSO4 •0.5H2O, CSH) were produced by heating gypsum (CaSO4 •2H2O). The morphology and particle sizes of α- and β-CSH were obtained by SEM, and their chemical properties were confirmed by EDS, FTIR and XRD. Furthermore, the DBM-based graft was mixed with α- or β-CSH at a ratio of 9:1, and glycerol/4% HPMC was added as a carrier to produce a putty. DBM/CSH putty possesses a low washout rate, good mechanical strength and biocompatibility. In conclusion, we believe that the moldable DBM/CSH composite putty developed in this study could be a promising substitute for the currently available bone grafts, and might have practical application in the orthopedics field as a potential bone void filler.

Osseous Healing Using Injectable Calcium Sulfate-Based Putty for the Delivery of Demineralized Bone Matrix and Cancellous Bone Chips

Orthopedics ◽  
2003 ◽  
Vol 26 (5) ◽  
Author(s):  
Thomas M Turner ◽  
Robert M Urban ◽  
Deborah J Hall ◽  
Susan Infanger ◽  
Steven Gitelis ◽  
...  
Keyword(s):  
Cancellous Bone ◽  
Calcium Sulfate ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Demineralized Bone

Healing of Large Defects Treated With Calcium Sulfate Pellets Containing Demineralized Bone Matrix Particles

Orthopedics ◽  
2003 ◽  
Vol 26 (5) ◽  
Author(s):  
Robert M Urban ◽  
Thomas M Turner ◽  
Deborah J Hall ◽  
Susan Infanger ◽  
N Cheema ◽  
...  
Keyword(s):  
Calcium Sulfate ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Demineralized Bone

scholarly journals Osteoformation potential of an allogenic partially demineralized bone matrix in critical-size defects in the rat calvarium

2021 ◽  
pp. 112207
Author(s):  
Ahmad Moustapha Diallo ◽  
Solène Rota ◽  
Michel Boissière ◽  
Raphaël Bardonnet ◽  
Emmanuel Pauthe ◽  
...  
Keyword(s):  
Critical Size ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Critical Size Defects ◽  
Demineralized Bone

Comparative Assessment of Autogenous Cancellous Bone Graft and Bovine-Derived Demineralized Bone Matrix for Secondary Alveolar Bone Grafting in Patients With Unilateral Cleft Lip and Palate

2021 ◽  
pp. 105566562110251
Author(s):  
Vijay Kumar ◽  
Vidya Rattan ◽  
Sachin Rai ◽  
Satinder Pal Singh ◽  
Jai Kumar Mahajan
Keyword(s):  
Bone Graft ◽  
Iliac Crest ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Volumetric Analysis ◽  
Group I ◽  
Alveolar Bone Grafting ◽  
Group Ii ◽  
Demineralized Bone

Objective: Comparison between bovine-derived demineralized bone matrix (DMBM) and iliac crest graft over long term for secondary alveolar bone grafting (SABG) in patients with unilateral cleft lip and palate (UCLP) in terms of radiological and clinical outcomes. Design: Prospective, randomized, parallel groups, double-blind, controlled trial. Setting: Unit of Oral and Maxillofacial Surgery, Oral Health Science Centre, Postgraduate Institute of Medical Education & Research, Chandigarh. Participants: Twenty patients with UCLP. Interventions: Patients were allocated into group I (Iliac crest bone graft) and group II (DMBM) for SABG. Outcomes were assessed at 2 weeks, 6 months, and then after mean follow-up period of 63 months. Outcomes Measures: Volumetric analysis of the grafted bone in the alveolar cleft site was done through cone beam computed tomography using Cavalieri principle and modified assessment tool. Clinical assessment was performed in terms of pain, swelling, duration of hospital stay, cost of surgery, alar base symmetry, and donor site morbidity associated with iliac crest harvesting. Results: Volumetric analysis through Cavalieri principle revealed comparable bone uptake at follow-up of 6 months between group I (70%) and group II (69%). Modified assessment tool showed no significant difference between horizontal and vertical bone scores over short- and long-term follow-up. In group II, there was higher cost of surgery, but no donor site morbidity unlike group I. Conclusions: Demineralized bone matrix proved analogous to iliac crest bone graft as per volumetric analysis over shorter period. However, although statistically insignificant, net bone volume achieved was lower than the iliac crest graft at longer follow-up.

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