Adrenogenital syndrome, or Congenital Adrenal Hyperplasia, is caused by a congenital insufficiency of the enzyme 21-hydroxylase, which is responsible for converting cortisol into cholesterol. Because of virilizing effect of androgens and its over- production, girls develop clitoral hypertrophy or Clitoromegaly. Clitoromegaly is an embarrassing condition, causing psychological stress to young girls and, hence requiring intervention. The goals of clitoroplasty are to achieve normal genital anatomy and to preserve tactile sensation with a satisfactory sexual response. We present a case of Adrenogenital syndrome with Clitoromegaly managed by reduction Clitoroplasty, preserving the dorsal neurovascular bundle and extensive network of nerves around the corpora to the glans and there by preserving the tactile sensation of the clitoris.
Psychological impact of congenital adrenal hyperplasia on adolescent and young girls in Saudi Arabia
