scholarly journals A multimodal approach to eye melanoma: patterns of care and related complications

10.4081/76 ◽  
2011 ◽  
Vol 3 (1) ◽  
Author(s):  
Maria Grazia Fabrini ◽  
Federica Genovesi-Ebert ◽  
Franco Perrone ◽  
Letizia Forte ◽  
Antonella Grandinetti ◽  
...  

Author(s):  
M. Fabrini ◽  
F. Genovesi-Ebert ◽  
F. Perrone ◽  
A. Grandinetti ◽  
F. Cresti ◽  
...  


2009 ◽  
Vol 3 (1) ◽  
pp. 41-49
Author(s):  
Maria Grazia Fabrini ◽  
Federica Genovesi-Ebert ◽  
Franco Perrone ◽  
Letizia Forte ◽  
Antonella Grandinetti ◽  
...  


2011 ◽  
Vol 3 (1) ◽  
pp. 41
Author(s):  
Maria Grazia Fabrini ◽  
Federica Genovesi-Ebert ◽  
Franco Perrone ◽  
Letizia Forte ◽  
Antonella Grandinetti ◽  
...  

We describe the results of multimodal treatment of uveal and conjunctival melanomas. A retrospective analysis was performed on 54 patients treated with a multimodal approach between 2003 and 2008 in a single institution. Main outcome measures were survival, enucleation rate, local tumor control, visual function preservation and complications associated with treatments. The median follow-up was 33.4 months. The 5-year overall survival was 95.3%, the local recurrence was 3.7% and the 5-year enucleation was 9.4%. Vision preservation was achieved in 84% of cases. Observed complications were cataract, retinal detachment, diplopia, glaucoma, retinopathy, optic neuropathy and scleral necrosis. A careful consideration of treatment of uveal melanoma in this study allowed us to obtain the survival rates and visual outcomes similar to previously published results, with a very small incidence of complications. the results must be interpreted in the light of recent findings on the genetic pattern of uveal melanoma.



2020 ◽  
Vol 29 (4) ◽  
pp. 2109-2130
Author(s):  
Lauren Bislick

Purpose This study continued Phase I investigation of a modified Phonomotor Treatment (PMT) Program on motor planning in two individuals with apraxia of speech (AOS) and aphasia and, with support from prior work, refined Phase I methodology for treatment intensity and duration, a measure of communicative participation, and the use of effect size benchmarks specific to AOS. Method A single-case experimental design with multiple baselines across behaviors and participants was used to examine acquisition, generalization, and maintenance of treatment effects 8–10 weeks posttreatment. Treatment was distributed 3 days a week, and duration of treatment was specific to each participant (criterion based). Experimental stimuli consisted of target sounds or clusters embedded nonwords and real words, specific to each participants' deficit. Results Findings show improved repetition accuracy for targets in trained nonwords, generalization to targets in untrained nonwords and real words, and maintenance of treatment effects at 10 weeks posttreatment for one participant and more variable outcomes for the other participant. Conclusions Results indicate that a modified version of PMT can promote generalization and maintenance of treatment gains for trained speech targets via a multimodal approach emphasizing repeated exposure and practice. While these results are promising, the frequent co-occurrence of AOS and aphasia warrants a treatment that addresses both motor planning and linguistic deficits. Thus, the application of traditional PMT with participant-specific modifications for AOS embedded into the treatment program may be a more effective approach. Future work will continue to examine and maximize improvements in motor planning, while also treating anomia in aphasia.



2005 ◽  
Vol 173 (4S) ◽  
pp. 57-58
Author(s):  
David F. Penson ◽  
June Chan ◽  
Susan Polich ◽  
Christopher S. Saigal ◽  
Mark S. Litwin


Skull Base ◽  
2007 ◽  
Vol 16 (S 1) ◽  
Author(s):  
Anthony Zeitouni ◽  
Richard Leblanc ◽  
Peter Abou Jaoude ◽  
Labib Soualmi


2012 ◽  
Vol 6 (1) ◽  
pp. 47-63
Author(s):  
Stephen Pihlaja

Using membership categorization analysis, this article investigates membership categories in a YouTube video made by an Evangelical Christian in which he differentiates between “saved” and “religious” users. Analysis will take a discourse-centred, multimodal approach grounded in longitudinal observation, using analysis of video discourse to instruct analysis of video images and user comments. Findings will show that categorization is accomplished by using recognized categories with ambiguous descriptions of category-bound activities that include metaphors, such as “being hungry for God” and not “hanging out with atheists.” These categories are recognized by commenters on the video, but the category bound activities applied to the category members are disputed. Findings will also show that scriptural reference plays an important role in categorization in the video, drawing on direct Bible quotes as well as paraphrases of key passages.



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