scholarly journals A case of endocarditis with cerebral embolism successfully treated with daptomycin

2011 ◽  
Vol 1 (4) ◽  
pp. 92
Author(s):  
Roberta Doria ◽  
Enrico Tagliaferri ◽  
Giovanni Andreotti ◽  
Riccardo Taddei ◽  
Rubinia Nardini ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Prophylaxis ◽  
American Heart Association ◽  
American Heart ◽  
Cerebral Aneurysms ◽  
Heart Association ◽  
Young Girl ◽  
Dental Procedures ◽  
Mitral Prolapse ◽  
History Of

A young girl was admitted for fever, headache, paresthesia of the hands, involuntary blinking of the left eye and aphasia. Imaging revealed mycotic cerebral aneurysms and finally infective endocarditis was diagnosed and successfully treated with daptomycin. She had a history of mitral prolapse and she had undergone dental procedures some months before without any antibiotic prophylaxis, according to the 2007 guidelines of the American Heart Association.

scholarly journals KNOWLEDGE AND AWARENESS REGARDING ANTIBIOTIC PROPHYLAXIS FOR INFECTIVE ENDOCARDITIS AMONG UNDERGRADUATE DENTAL STUDENTS

2016 ◽  
pp. 154 ◽  
Author(s):  
Santhosh Kumar ◽  
Sneha S
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Prophylaxis ◽  
American Heart ◽  
Heart Association ◽  
Dental Students ◽  
Basic Knowledge ◽  
First Line ◽  
Validated Questionnaire ◽  
Dental Procedures ◽  
Teaching Curriculum

<p>ABSTRACT<br />Objective: To evaluate the knowledge and awareness regarding antibiotic prophylaxis for infective endocarditis (IE) among undergraduate dental<br />students.<br />Methods: A validated questionnaire of 16 questions, regarding the basic knowledge and awareness about antibiotic prophylaxis for the prevention<br />of IE, was distributed among 100 students randomly belonging to final year and internship (5<br /> year trainee) of the undergraduate dental program in<br />Saveetha Dental College and Hospital, Saveetha University, Chennai. The data extracted were tabulated, statistically analyzed, and results obtained.<br />Results were calculated on the basis of frequency and percentages using SPSS Version 20.0.<br />th<br />Results: About 73% of the students were aware of IE prophylaxis, and 40% of dental students were exposed to treating patients susceptible to IE.<br />56% of participants answered that amoxicillin is the first line of antibiotic for IE prophylaxis and 59% replied 2 g PO 1 hr before the appointment is<br />the recommended regimen. 36% said that erythromycin is no longer recommended by American Heart Association for IE prophylaxis. However, only<br />one-third of the participants knew about the cardiac conditions and dental procedures that require antibiotic prophylaxis for the prevention of IE.<br />Furthermore, only 16% knew about the recommended dosage of clindamycin.<br />Conclusion: This study revealed a reasonable knowledge and awareness about IE prophylaxis among undergraduate dental students but was<br />inadequate. Hence, this study emphasizes the need for improved education in the teaching curriculum for dental students regarding IE prophylaxis.<br />A standard protocol regarding the training as well as preventive measures for IE should be formulated for the dental students and the knowledge<br />acquired must be transferred into practice.<br />Keywords: Infective endocarditis, Prophylaxis, Antibiotics, Dental students, Knowledge.</p>

scholarly journals Antibiotic Prophylaxis of Infective Endocarditis: From the History of the Concept to Modern Recommendations (Review)

2020 ◽  
Vol 10 (2) ◽  
pp. 119-130
Author(s):  
G. G. Taradin ◽  
E. Yu. Ponomareva ◽  
G. A. Ignatenko ◽  
N. T. Vatutin ◽  
B. D. Prendergast
Keyword(s):  
Infective Endocarditis ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Clinical Excellence ◽  
Concept Development ◽  
Antibacterial Prophylaxis ◽  
Fatality Rate ◽  
History Of ◽  
European Society Of Cardiology

The presented review highlights current understandings of prophylaxis for infective endocarditis (IE). The historic aspects of the concept development of antibacterial prophylaxis (ABP) for IE, the main approaches and the rationale for changing the principles of ABP in recent years are described. There are detailed clarifications of published international and national recommendations, in particular, of European Society of Cardiology, National Institute for Health and Clinical Excellence, American Heart Association/American College of Cardiology and Japanese Circulation Society. The critical estimation of earlier adopted international guidelines with analysis of influence of partial or absolute ABP restrictions on the incidence of IE and its complications including fatality rate are presented.

scholarly journals Infective endocarditis: prevention and antibiotic prophylaxis

2020 ◽  
Author(s):  
Keyword(s):  
Infectious Disease ◽  
Infective Endocarditis ◽  
Infectious Diseases ◽  
Antibiotic Prophylaxis ◽  
American Heart Association ◽  
Pediatric Cardiology ◽  
American Heart ◽  
Heart Association ◽  
Disease Group ◽  
Endocarditis Prophylaxis

After considerable revision of the previous guidelines on infective endocarditis prophylaxis by the American Heart Association in 2007, the Swiss recommendations were revised and published accordingly in 2008. The Swiss societies of Infectious Diseases (SSI), Pediatric Cardiology and Cardiology and the Pediatric Infectious Disease Group of Switzerland present the current update in a joint initiative.

scholarly journals Prevention of Viridans Group Streptococcal Infective Endocarditis: A Scientific Statement From the American Heart Association

Circulation ◽  
2021 ◽  
Author(s):  
Walter R. Wilson ◽  
Michael Gewitz ◽  
Peter B. Lockhart ◽  
Ann F. Bolger ◽  
Daniel C. DeSimone ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Prophylaxis ◽  
American Heart Association ◽  
English Language ◽  
American Heart ◽  
Adverse Outcome ◽  
Critical Role ◽  
Heart Association ◽  
Convincing Evidence ◽  
Randomized Controlled Studies

BACKGROUND: In 2007, the American Heart Association published updated evidence-based guidelines on the recommended use of antibiotic prophylaxis to prevent viridans group streptococcal (VGS) infective endocarditis (IE) in cardiac patients undergoing invasive procedures. The 2007 guidelines significantly scaled back the underlying conditions for which antibiotic prophylaxis was recommended, leaving only 4 categories thought to confer the highest risk of adverse outcome. The purpose of this update is to examine interval evidence of the acceptance and impact of the 2007 recommendations on VGS IE and, if needed, to make revisions based on this evidence. METHODS AND RESULTS: A writing group was formed consisting of experts in prevention and treatment of infective endocarditis including members of the American Dental Association, the Infectious Diseases Society of America, and the American Academy of Pediatrics, in addition to the American Heart Association. MEDLINE database searches were done for English language articles on compliance with the recommendations in the 2007 guidelines and the frequency of and morbidity or mortality from VGS IE after publication of the 2007 guidelines. Overall, there was good general awareness of the 2007 guidelines but variable compliance with recommendations. There was no convincing evidence that VGS IE frequency, morbidity, or mortality has increased since 2007. CONCLUSIONS: On the basis of a review of the available evidence, there are no recommended changes to the 2007 VGS IE prevention guidelines. We continue to recommend VGS IE prophylaxis only for categories of patients at highest risk for adverse outcome while emphasizing the critical role of good oral health and regular access to dental care for all. Randomized controlled studies to determine whether antibiotic prophylaxis is effective against VGS IE are needed to further refine recommendations.

Infective Endocarditis Prophylaxis

2012 ◽  
Author(s):  
John W. Wilson ◽  
Lynn L. Estes
Keyword(s):  
Infective Endocarditis ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Endocarditis Prophylaxis ◽  
Major Revision ◽  
Dental Procedures

The guidelines for the prevention of infective endocarditis (IE) issued by the American Heart Association underwent a major revision in 2007. Key changes include the following: • Dental procedures have been found to be associated with a small number of cases of IE. Thus, even if prophylaxis was 100% effective, it would prevent only an extremely small number of cases....

Abstract 13134: Impact of the American Heart Association’s 2007 Guidelines on the Practice of Dental Prophylaxis for the Prevention of Infective Endocarditis in Olmsted County, Minnesota

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Daniel C DeSimone ◽  
Abdelghani El Rafei ◽  
Alan B Carr ◽  
Walter A Rocca ◽  
Jennifer St. Sauver ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Prophylaxis ◽  
American Heart ◽  
Heart Association ◽  
Olmsted County ◽  
Dental Procedures ◽  
Cardiac Condition ◽  
Prevention Guidelines ◽  
The Impact ◽  
To Receive

Background: In 2007, the American Heart Association (AHA) infective endocarditis (IE) prevention guidelines recommended that antibiotic prophylaxis before invasive dental procedures for the “moderate risk” (MR) group, which represented the bulk of patients who were to receive prophylaxis before 2007, be eliminated. This decision was met with much concern among some healthcare providers and that concern persists today. We therefore evaluated dental office records in Olmsted County (OC), Minnesota to determine whether patients included in the MR group continue to receive antibiotic prophylaxis despite the 2007 AHA recommendations. Methods: Eligible patients include all adult (≥18 years) residents of OC, classified as having MR cardiac condition for IE (i.e. mitral valve prolapse [MVP], bicuspid aortic valve [BAV], hypertrophic obstructive cardiomyopathy [HOCM], acquired valvular dysfunction [AVD]), with at least one dental visit between January 1, 2005 and June 1, 2015. Eight dental offices located within OC were sampled to identify both dental procedures and whether antibiotic prophylaxis was administered according to AHA guidelines. Results: We identified 334 MR patients. Approximately 62% of MR patients received antibiotic prophylaxis prior to the change in AHA guidelines in 2007. There was a decrease to 7% post-2007 AHA guidelines (P<.001). The magnitude of decline was greater among visits for dental cleanings (from 63% to 6%), as compared to other invasive procedures (57% to 11%; P=0.003) (Figure 1). AVD was the most common cardiac condition (85%), followed by MVP (8%), and BAV (4%). Conclusion: Following publication of the 2007 AHA IE prevention guidelines, there was a rapid, 9-fold decrease in antibiotic prophylaxis in patients with MR cardiac conditions who underwent invasive dental procedures in OC. These data are also critical as we attempt to evaluate the impact, if any, of this practice on the incidence of IE due to viridans group streptococci.

scholarly journals Antibiotic Prophylaxis of Infective Endocarditis: From the History of the Concept to Modern Recommendations (Review)

2020 ◽  
Vol 10 (2) ◽  
pp. 119-130
Author(s):  
G. G. Taradin ◽  
E. Yu. Ponomareva ◽  
G. A. Ignatenko ◽  
N. T. Vatutin ◽  
B. D. Prendergast
Keyword(s):  
Infective Endocarditis ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Clinical Excellence ◽  
Concept Development ◽  
Antibacterial Prophylaxis ◽  
Fatality Rate ◽  
History Of ◽  
European Society Of Cardiology

The presented review highlights current understandings of prophylaxis for infective endocarditis (IE). The historic aspects of the concept development of antibacterial prophylaxis (ABP) for IE, the main approaches and the rationale for changing the principles of ABP in recent years are described. There are detailed clarifications of published international and national recommendations, in particular, of European Society of Cardiology, National Institute for Health and Clinical Excellence, American Heart Association/American College of Cardiology and Japanese Circulation Society. The critical estimation of earlier adopted international guidelines with analysis of influence of partial or absolute ABP restrictions on the incidence of IE and its complications including fatality rate are presented.

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