scholarly journals Clinical, dermoscopic and histological features of a combined tumor composed of a melanoma in situ, a basal cell carcinoma and an intradermal naevus

2012 ◽  
Vol 4 (1) ◽  
pp. 11
Author(s):  
Massimiliano Scalvenzi ◽  
Claudia Costa ◽  
Franco Palmisano ◽  
Gabriella Fabbrocini ◽  
Mariella Siano ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histological Features ◽  
Combined Tumor ◽  
Melanoma In Situ ◽  
Intradermal Naevus

Malignant Melanoma In Situ Colonizing Basal Cell Carcinoma

1997 ◽  
Vol 19 (3) ◽  
pp. 303-307 ◽  
Author(s):  
Ann Burkhalter ◽  
Wain L. White
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Melanoma In Situ

Variables Affecting Basal Cell Carcinoma and Melanoma In Situ Excision Clearance

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ajay N. Sharma ◽  
Joel L. Cohen ◽  
Eric C. Haupt ◽  
Hege G. Sarpa ◽  
Brent C. Martin
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Melanoma In Situ

scholarly journals Melanoma in situ colonizing basal cell carcinoma: a case report and review of the literature

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Silvia Mancebo ◽  
Michael Marchetti ◽  
Travis Hollmann ◽  
Ashfaq Marghoob ◽  
Klaus Busam ◽  
...  
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Review Of The Literature ◽  
Melanoma In Situ

scholarly journals Melanoma in situ or superficial basal cell carcinoma?

2015 ◽  
Vol 21 (6) ◽  
Author(s):  
Andre Laureano
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Melanoma In Situ ◽  
Superficial Basal Cell Carcinoma

scholarly journals Collision Cutaneous Neoplasms Consisting of Melanoma and Basal Cell Carcinoma

2021 ◽  
pp. 2021037
Author(s):  
Maryam Aghighi ◽  
David Chercover ◽  
Maral Rahvar
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Clinical Impression ◽  
Anatomical Location ◽  
Melanoma In Situ ◽  
Collision Tumors ◽  
Lateral Canthus ◽  
Lentigo Maligna Melanoma

Collision tumors are defined as two histologically different tumor types that arise at the same anatomical location. According to the literature review performed, there are reports of 27 cases of collision tumors involving lentigo maligna melanoma (LMM) in-situ and basal cell carcinoma (BCC). In the absence of melanocytic extension beyond the lamina propria of the BCC compartment, mixed tumors are considered as melanoma in-situ colonizing the BCC, rather than invasive melanomas. We report an uncommon case of collision of BCC with LMM, two primary skin tumors that are seen in patients with significant sunlight exposure. In our case, the patient is a 91-year-old male presented with a translucent plaque with areas of brown pigmentation on his left lateral canthus. He had a history of multiple BCCs, squamous cell carcinomas and an invasive melanoma of right cheek. Given the clinical impression of BCC, the lesion was curetted. Histological examination demonstrated melanoma in-situ heavily infiltrating the dermal nodules of BCC. Deposits of melanin pigment were scattered throughout the tumor. The BCC contained about 50% atypical melanocytes. Further immunohistochemical evaluation with melanocytic and epithelial markers (melanin A, SOX-10, pan-cytokeratin and p63) confirmed the diagnosis. An unequivocal independent invasive melanoma component was not identified in this material. The collision of BCC and LMM is very rare.  However, given the sun-damaged changes promote both tumors, their development at the same site, although unexpected, can be explained. Since the prognosis of the two entities is independent, wider excision to exclude invasive malignant melanoma is indicated.

Basal Cell Carcinoma of Prostate With MSMB–NCOA4 Fusion and a Probable Basal Cell Carcinoma In Situ: Case Report

2021 ◽  
pp. 106689692110173
Author(s):  
Vilde Pedersen ◽  
Katrine S. Petersen ◽  
Klaus Brasso ◽  
Olga Østrup ◽  
Anand C. Loya
Keyword(s):  
Prostate Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Carcinoma In Situ ◽  
Pathological Examination ◽  
Molecular Characteristics ◽  
Histological Lesion ◽  
Basal Cell Carcinomas

Basal cell carcinomas of prostate (BCCP) are very rare. Most arise in the transition zone and thus are associated with lower urinary tract symptoms and rarely associated with elevated prostate-specific antigen (PSA). These features make diagnosis/early diagnosis difficult because of the routine protocols followed. Basal cell carcinomas have distinctive histopathological, immunohistochemical, and to some extent also different molecular characteristics. Basal cell carcinoma in situ (BCCIS) is a nonexistent histological lesion as per the current literature, but here is an attempt to describe it through this case. A 74-year-old man presented with hematuria and previous diagnosis of prostatic hyperplasia. Based on this history, he underwent a prostatectomy ad modum Freyer. Pathological examination surprisingly revealed a diffusely infiltrative tumor with nonacinar adenocarcinoma morphology and many glandular structures probably representing BCCIS. Tumor was diagnosed as BCCP. Patient presented with metastasis to the abdominal wall 8 months postprostatectomy. BCCP is an aggressive type of prostate cancer, which might be challenging to diagnose based on routine protocols. This results in delayed diagnosis and treatment and thus poor prognosis. Furthermore, patients with this subtype of prostate cancer need appropriately designed, and maybe a totally different follow-up regimen as PSA is of no use for BCCP patients. Finally, diagnosis of BCCIS, if agreed upon its existence needs to be studied in larger cohorts as a precursor lesion.

scholarly journals Colonisation of basal cell carcinoma and actinic keratosis by malignant melanoma in situ in a patient with xeroderma pigmentosum variant

2012 ◽  
Vol 2 (2) ◽  
pp. 47 ◽  
Author(s):  
Louise J. Smith ◽  
Ehab A. Husain
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Actinic Keratosis ◽  
Xeroderma Pigmentosum ◽  
Clinical Impression ◽  
Anatomical Site ◽  
History Of

Although malignant melanoma (MM) and both basal cell carcinoma (BCC) and actinic keratosis (AK) are sun-induced lesions, the coexistence of these entities at the same anatomical site (collision tumour) is exceedingly rare. We report the case of a 54-year-old woman with a known history of xeroderma pigmentosum variant (XPV) who presented with 2 separate skin lesions over the middle and upper right forearm, respectively. The clinical impression was that of BCCs or squamous cell lesions. On histological examination, both specimens showed features of melanoma <em>in situ </em>(MIS). In the first lesion, MIS merged with and colonised a superficial and focally invasive BCC. In the second lesion, MIS merged with an AK. No separate invasive nests of malignant melanoma were seen in either specimen. The atypical melanocytes were highlighted by Melan-A and HMB-45 immunostaining, whereas the epithelial cells in both the BCC and AK stained with the pancytokeratin MNF-116. The patient had a previous history of multiple MMs and non-melanomatous skin cancers and finally developed widespread metastatic malignant melanoma, which proved fatal. The rare and interesting phenomenon of collision tumours may pose diagnostic difficulties. To our knowledge, this is the first reported simultaneous presentation of cytologically malignant collision tumours in a patient with XPV.

Dermoscopic Differentiation of a Superficial Basal Cell Carcinoma and Squamous Cell Carcinoma In Situ

2006 ◽  
Vol 32 (3) ◽  
pp. 423-425 ◽  
Author(s):  
SETH FELDER ◽  
HAROLD RABINOVITZ ◽  
MARGARET OLIVIERO ◽  
ALFRED KOPF
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Carcinoma In Situ ◽  
Superficial Basal Cell Carcinoma
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