scholarly journals Gestational and Neurodevelopmental Outcomes Associated With Antipsychotic Drug Exposure During Pregnancy

2021 ◽  
Vol 82 (5) ◽  
Author(s):  
Chittaranjan Andrade
Keyword(s):  
Antipsychotic Drug ◽  
Drug Exposure ◽  
Neurodevelopmental Outcomes ◽  
Exposure During Pregnancy

scholarly journals Serotonin Syndrome Associated with Antidepressant Discontinuation in a Neonate Following Drug Exposure During Pregnancy

2021 ◽  
Vol 5 (5) ◽  
pp. CR1-CR2
Author(s):  
Dolma Gurung ◽  
Sunil Borah ◽  
Sameer Wangu
Keyword(s):  
Serotonin Syndrome ◽  
Drug Exposure ◽  
Healthcare Professionals ◽  
Involuntary Movement ◽  
Baby Girl ◽  
Treatment Of Depression ◽  
The Subject ◽  
Exposure During Pregnancy

Sudden withdrawal of some drugs leads to withdrawal issues. We describe a baby girl who was indirectly exposed to venlafaxine as her mother was administered this drug during pregnancy for treatment of depression. The subject presented with involuntary movement of the limbs. The mother had also encountered similar scenario along with some other symptoms after she suddenly discontinued her medication. The symptoms of the mother completely resolved a few hours after the she took another dose of venlafaxine. The baby was kept under observation and recovered completely without any intervention. We suggest that healthcare professionals should be aware that patients may require tapering of anti-depressants before discontinuation.

Increased volume and glial density in primate prefrontal cortex associated with chronic antipsychotic drug exposure

1999 ◽  
Vol 46 (2) ◽  
pp. 161-172 ◽  
Author(s):  
Lynn D. Selemon ◽  
Michael S. Lidow ◽  
Patricia S. Goldman-Rakic
Keyword(s):  
Prefrontal Cortex ◽  
Antipsychotic Drug ◽  
Drug Exposure

Antipsychotic Drug Exposure in a Health Maintenance Organization

Medical Care ◽  
1993 ◽  
Vol 31 (5) ◽  
pp. 432-444 ◽  
Author(s):  
RICHARD E. JOHNSON ◽  
BENTSON H. MCFARLAND
Keyword(s):  
Antipsychotic Drug ◽  
Drug Exposure ◽  
Health Maintenance Organization ◽  
Health Maintenance

scholarly journals Testing the programming of temperament and psychopathology in two independent samples of children with prenatal substance exposure

2018 ◽  
Vol 30 (3) ◽  
pp. 1023-1040 ◽  
Author(s):  
Betty Lin ◽  
Brendan D. Ostlund ◽  
Elisabeth Conradt ◽  
Linda L. Lagasse ◽  
Barry M. Lester
Keyword(s):  
Externalizing Behavior ◽  
Latent Profile Analysis ◽  
Drug Exposure ◽  
Growth Parameters ◽  
Equation Modeling ◽  
Prenatally Exposed ◽  
Neurodevelopmental Outcomes ◽  
Prenatal Substance Exposure ◽  
Substance Exposure ◽  
Internalizing And Externalizing

AbstractPrenatal programming models have rarely been applied to research on children with prenatal substance exposure, despite evidence suggesting that prenatal drug exposure is a form of stress that impacts neurodevelopmental outcomes and risk for psychopathology. Utilizing data from two longitudinal multisite studies comprising children prenatally exposed to substances as well as a nonexposed comparison group (Maternal Lifestyle Study, n = 1,388; Infant Development, Environment, and Lifestyle study, n = 412), we tested whether early phenotypic indicators of hypothesized programming effects, indexed by growth parameters at birth and infant temperament, served as a link between prenatal substance exposure and internalizing and externalizing behavior at age 5. Latent profile analysis indicated that individual differences in reactivity and regulation for infants prenatally exposed to substances was best characterized by four temperament profiles. These profiles were virtually identical across two independent samples, and demonstrated unique associations with adjustment difficulties nearly 5 years later. Results of path analysis using structural equation modeling also showed that increased prenatal substance exposure was linked to poorer growth parameters at birth, profiles of temperamental reactivity in infancy, and internalizing and externalizing behavior at age 5. This pathway was partially replicated across samples. This study was among the first to link known individual-level correlates of prenatal substance exposure into a specific pathway to childhood problem behavior. Implications for the developmental origins of a child's susceptibility to psychopathology as a result of intrauterine substance exposure are discussed.

Inferred Brain Cell-Type Shifts Accompany Schizophrenia and Bipolar Disorder and Differentially Correlate With Antipsychotic Drug Exposure

2021 ◽  
Vol 89 (9) ◽  
pp. S118-S119
Author(s):  
Anton Schulmann ◽  
Stefano Marenco ◽  
Nirmala Akula ◽  
Pavan Auluck ◽  
Barbara Lipska ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Antipsychotic Drug ◽  
Drug Exposure ◽  
Brain Cell ◽  
Cell Type

Drug Exposure During Pregnancy: Some Epidemiologic Considerations

1983 ◽  
Vol 26 (2) ◽  
pp. 418-428 ◽  
Author(s):  
Jos?? F. Cordero ◽  
Godfrey P. Oakley
Keyword(s):  
Drug Exposure ◽  
Exposure During Pregnancy
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