Levomilnacipran for Negative Symptom Domain Schizophrenia

2021 ◽  
Vol 23 (6) ◽  
Author(s):  
Ahmed Naguy
Keyword(s):  
Negative Symptom

Negative Symptom Scale

2001 ◽  
Author(s):  
Ellen S. Herbener ◽  
Martin Harrow
Keyword(s):  
Negative Symptom ◽  
Symptom Scale

Patients with deficit, nondeficit, and negative symptom schizophrenia: Do they differ during episodes of acute psychotic decompensation?

1997 ◽  
Vol 24 (3) ◽  
pp. 341-348 ◽  
Author(s):  
G SPALLETTA ◽  
A PASINI ◽  
F DEANGELIS ◽  
A TROISI
Keyword(s):  
Negative Symptom

scholarly journals Avolition as the core negative symptom in schizophrenia: relevance to pharmacological treatment development

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Gregory P. Strauss ◽  
Lisa A. Bartolomeo ◽  
Philip D. Harvey
Keyword(s):  
Negative Symptom ◽  
Negative Symptoms ◽  
Clinical Trial Design ◽  
Core Component ◽  
Treatment Target ◽  
Global Improvement ◽  
Treatment Development ◽  
The Core ◽  
Current Review ◽  
Symptom Domains

AbstractNegative symptoms have long been considered a core component of schizophrenia. Modern conceptualizations of the structure of negative symptoms posit that there are at least two broad dimensions (motivation and pleasure and diminished expression) or perhaps five separable domains (avolition, anhedonia, asociality, blunted affect, alogia). The current review synthesizes a body of emerging research indicating that avolition may have a special place among these dimensions, as it is generally associated with poorer outcomes and may have distinct neurobiological mechanisms. Network analytic findings also indicate that avolition is highly central and interconnected with the other negative symptom domains in schizophrenia, and successfully remediating avolition results in global improvement in the entire constellation of negative symptoms. Avolition may therefore reflect the most critical treatment target within the negative symptom construct. Implications for targeted treatment development and clinical trial design are discussed.

Rasch analysis of the PANSS negative subscale and exploration of negative symptom trajectories in first-episode schizophrenia – data from the OPTiMiSE trial

2020 ◽  
Vol 289 ◽  
pp. 112970 ◽  
Author(s):  
Lone Baandrup ◽  
Peter Allerup ◽  
Mette Ø. Nielsen ◽  
Nikolaj Bak ◽  
Signe W. Düring ◽  
...  
Keyword(s):  
Negative Symptom ◽  
Rasch Analysis ◽  
First Episode ◽  
Symptom Trajectories ◽  
First Episode Schizophrenia

scholarly journals Genetic Variation Throughout the Folate Metabolic Pathway Influences Negative Symptom Severity in Schizophrenia

2011 ◽  
Vol 39 (2) ◽  
pp. 330-338 ◽  
Author(s):  
J. L. Roffman ◽  
D. G. Brohawn ◽  
A. Z. Nitenson ◽  
E. A. Macklin ◽  
J. W. Smoller ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Negative Symptom ◽  
Metabolic Pathway ◽  
Symptom Severity

PHARMACOGENETICS OF NEGATIVE SYMPTOM RESPONSE TO ANTIPSYCHOTIC DRUGS - THE ROLE OF 5-HT SYSTEMS

2008 ◽  
Vol 102 (1-3) ◽  
pp. 259
Author(s):  
Gavin Reynolds ◽  
James Armstrong ◽  
Suzanne Barrett ◽  
Ciaran Mulholland ◽  
Richard Anderson ◽  
...  
Keyword(s):  
Negative Symptom ◽  
Antipsychotic Drugs ◽  
Symptom Response

Poster #T146 DELAYS TO TREATMENT PREDICT PERSISTENT NEGATIVE SYMPTOM DOMAINS

2014 ◽  
Vol 153 ◽  
pp. S341-S342
Author(s):  
John Paul Lyne ◽  
Laoise Renwick ◽  
Brian O'Donoghue ◽  
Kevin Madigan ◽  
Tim Grant ◽  
...  
Keyword(s):  
Negative Symptom ◽  
Symptom Domains

Negative symptoms in bipolar disorder and schizophrenia: A psychometric evaluation of the brief negative symptom scale across diagnostic categories

2016 ◽  
Vol 170 (2-3) ◽  
pp. 285-289 ◽  
Author(s):  
Gregory P. Strauss ◽  
Mary Vertinski ◽  
Sally J. Vogel ◽  
Erik N. Ringdahl ◽  
Daniel N. Allen
Keyword(s):  
Bipolar Disorder ◽  
Negative Symptom ◽  
Negative Symptoms ◽  
Psychometric Evaluation ◽  
Symptom Scale ◽  
Diagnostic Categories

Brief Negative Symptom Scale--Polish Version

2019 ◽  
Author(s):  
Paweł Wójciak ◽  
Krystyna Górna ◽  
Klaudia Domowicz ◽  
Krystyna Jaracz ◽  
Katarzyna Gołębiewska ◽  
...  
Keyword(s):  
Negative Symptom ◽  
Symptom Scale ◽  
Polish Version
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