Introduction: Breast cancer is second most common cancer all over the world. Majority of breast cancer cases are registered to hospital at a later stage of cancer presentation. Objective: To study socio-demographic, clinical presentation and outcome of Breast cancer patients attending tertiary care centre of Gujarat state. Method: This was a retrospective study made up of 5774 patients registered in tertiary care centre of Gujarat state. Data including patient’s socio-demographic information like age, marital status, education level and clinical diagnosis including clinical presentation at time of registration, treatment history etc was collected. The data was analysed using MS office 2010 and Epi Info software version 7.0. Result: The age ranged between 17-99 years, with a median of 50 years and interquartile range of 42-58 years. There were 62.07% patients presented with locally advanced breast cancer, while 17.57% patients had distant metastasis at diagnosis. Significant association (p<0.05) was found between presentation of disease and literacy status. The overall Kaplan-Meier survival rate at 5 years was 35.8% + 5.0%. Survival rate was consistently declining with increase in clinical extension of disease. Conclusion: Majority of patients were in early advanced stage during their first hospital visit which was associated with poor survival. This information may help authorities to focus on early diagnosis of breast cancer.
Outcome of neoadjuvant chemotherapy in locally advanced breast cancer: A tertiary care centre experience
