scholarly journals Sarcomatoid chromophobe renal cell carcinoma: A rare entity with prognostic significance

2015 ◽  
Vol 11 (4) ◽  
pp. 1030 ◽  
Author(s):  
Reetika Sharma ◽  
Vijay Kaushal
Author(s):  
Takashi Karashima ◽  
Naoto Kuroda ◽  
Takahiro Taguchi ◽  
Hideo Fukuhara ◽  
Takahira Kuno ◽  
...  

AbstractA novel variant of chromophobe renal cell carcinoma showing an oncocytic phenotype is proposed. Two new cases of this rare entity are presented and discussed along with six previous cases from our colleagues. A 76-year-old man and a 78-year-old man had a 3.4-cm and a 3.2-cm-diameter renal mass, respectively. On histopathological examination of surgical specimens, uniform eosinophilic cuboidal cells without a perinuclear halo growing in a tubular pattern were seen, and differential diagnosis from oncocytoma was necessary. Immunohistochemical staining for cytokeratin 7 and E-cadherin showed diffusely positive patterns in both, as in the previous reports. Although monosomy of chromosomes 7, 10, 13, and 17 was commonly observed in the previous reports, gains of chromosome 19 were observed in the two present cases. Immunohistochemical and cytogenetic approaches lead to exclusion of oncocytoma and the diagnosis of an oncocytic variant of chromophobe renal cell carcinoma.


2007 ◽  
Vol 51 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Javier Salamanca ◽  
Nuria Alberti ◽  
Fernando López-Ríos ◽  
Andrés Perez-Barrios ◽  
Miguel Angel Martínez-González ◽  
...  

2021 ◽  
Vol 160 ◽  
pp. 103287 ◽  
Author(s):  
Rohan Garje ◽  
Dean Elhag ◽  
Hesham A Yasin ◽  
Luna Acharya ◽  
Daniel Vaena ◽  
...  

2004 ◽  
Vol 28 (8) ◽  
pp. 1045-1050 ◽  
Author(s):  
Kurt T Patton ◽  
Maria S Tretiakova ◽  
Jorge L Yao ◽  
Veronica Papavero ◽  
Lei Huo ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Noureddine Bouadel ◽  
Fahd El Ayoubi ◽  
A. Anass Bennani-Baiti ◽  
Mohamed Anas Benbouzid ◽  
Leila Essakalli ◽  
...  

The metastasis of chromophobe renal cell carcinoma to head and neck region, described herein, has never been reported before to our knowledge. A 56-year-old woman with a history of nephrectomy, that revealed chromophobe renal cell carcinoma six years before, presented left cervical mass. Imaging showed with left cervical lymphadenopathies and thyroid nodule. Surgery with histopathological examination confirmed that it was a left central and lateral jugular lymph node metastasis of chromophobe renal cell carcinoma treated postoperatively by antiangiogenic therapy. The patient was successfully treated by surgery and antiangiogenic drugs with stabilization and no recurrence of the metastatic disease. The case and the literature reported here support that chromophobe renal cell carcinoma can metastasize to the head and neck region and should preferentially be treated with surgery and antiangiogenic therapy because of the associated morbidity and quality-of-life issues.


1996 ◽  
Vol 3 (5) ◽  
pp. 336 ◽  
Author(s):  
Janet R. Durham ◽  
Mary Keohane ◽  
Mahul B. Amin

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