Low serum free and total tri-iodothyronine hormones as possible prognostic factors in liver cirrhotic patients because of chronic hepatitis C

2015 ◽  
Vol 43 (2) ◽  
pp. 46 ◽  
Author(s):  
MohamedA Tawfik ◽  
Abd-AllahA El-Sawy
2019 ◽  
Vol 7 ◽  
pp. 232470961985812
Author(s):  
Clara Y. Tow ◽  
John F. Reinus

In this era of direct-acting antiviral (DAA) therapy for chronic hepatitis C virus (HCV) infection, treated patients have extremely high rates of sustained virologic response to short courses of therapy regardless of stage of fibrosis. Treatment failure is uncommon and often attributed to medication noncompliance or viral resistance to drug. This report describes 2 Child-Pugh-A cirrhotic patients who failed to clear HCV in response to therapy with DAAs. Each patient had Roux-en-Y gastric bypass (RYGB) surgery preceding DAA therapy. RYGB may create multiple barriers to adequate DAA absorption as a result of changes in gastrointestinal physiology. Treatment monitoring and duration should be carefully considered in this unique patient population.


2006 ◽  
Vol 44 ◽  
pp. S227 ◽  
Author(s):  
M.G. Swain ◽  
G.R. Foster ◽  
S.J. Hadzivannis ◽  
E.J. Heathcote ◽  
D. Jensen ◽  
...  

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