Isolated pancreatic tuberculosis: A diagnostic challenge!!

Isolated pancreatic tuberculosis is an exceedingly rare condition, even in areas of the world where the disease is highly prevalent. Abdominal tuberculosis is a common form of extrapulmonary tuberculosis but involvement of the pancreas is very rare. We report a case of isolated pancreatic tuberculosis presenting as a pancreatic mass in a patient with persistent abdominal pain and jaundice. Clinically and radiologically, the mass mimicked a malignant pancreatic tumor with a vastly different prognostic implication and therapeutic approach. Endoscopic ultrasound with fine-needle aspiration (EUS-FNA) can provide valuable diagnostic information in this scenario. After the tissue showed evidence of acid-fast bacilli and the cultures showed growth of Mycobacterium tuberculosis, antituberculosis therapy was initiated. Conservative management is usually successful in alleviating symptoms and leading to a cure. The excellent response to ATT makes it imperative that these patients are diagnosed early and managed appropriately to avoid unnecessary surgery and associated morbidity.

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Pancreatic tuberculosis: a clinical diagnostic challenge

ANZ Journal of Surgery ◽

10.1111/ans.16249 ◽

2020 ◽

Author(s):

Guangbo Wu ◽

Qiang Fan

Keyword(s):

Diagnostic Challenge ◽

Pancreatic Tuberculosis ◽

Clinical Diagnostic

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Isolated Pancreatic Tuberculosis Mimicking as Pancreatic Cancer: A Diagnostic Challenge

The American Journal of Gastroenterology ◽

10.14309/00000434-201710001-01395 ◽

2017 ◽

Vol 112 ◽

pp. S756-S757

Author(s):

Abhishek Bhurwal ◽

Muhammad Masoodul Haq ◽

Sunil Sapru ◽

Dhanasekaran Ramasamy

Keyword(s):

Pancreatic Cancer ◽

Diagnostic Challenge ◽

Pancreatic Tuberculosis

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A DIAGNOSTIC PITFALL: PANCREATIC TUBERCULOSIS MASQUERADING AS PANCREATIC CARCINOMA

10.36106/ijsr/3022992 ◽

2020 ◽

pp. 80-82

Author(s):

Amitrajit Dasgupta ◽

Indranil Banerjee

Keyword(s):

Weight Loss ◽

Endoscopic Ultrasound ◽

Rare Entity ◽

Ultrasound Guided ◽

Diagnostic Challenge ◽

Diagnostic Pitfall ◽

Pancreatic Tuberculosis ◽

High Incidence ◽

Hypoechoic Mass ◽

Pancreatic Lymph Nodes

Isolated cases of Pancreatic Tuberculosis remains a rare entity even in countries with a high incidence of Tuberculosis. It presents as a hypoechoic mass on ultrasonography and imaging mimicking pancreatic malignancy. Consequently, it represents a diagnostic challenge both clinically (due to a similar array of symptoms) and radiologically. The diagnosis often requires tissue biopsy. The possibility of TB should be considered in the list of differential diagnoses of pancreatic mass and an endoscopic, ultrasound-guided biopsy might help to clinch the diagnosis of this potentially curable disease. Here, we report a case with symptoms of abdominal pain, progressive jaundice, and anorexia and weight loss, diagnosed to be a case of Disseminated Tuberculosis (Pancreatic TB) following Endoscopic Ultrasound guided FNAC of peri-pancreatic lymph nodes.

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Pediatric Pancreatic Tuberculosis: A Case Report and Review of the Literature

Case Reports in Pediatrics ◽

10.1155/2018/5215128 ◽

2018 ◽

Vol 2018 ◽

pp. 1-3

Author(s):

Yajun Zhang ◽

Yuhong Tao

Keyword(s):

Elevated Serum ◽

Signs And Symptoms ◽

Ca 125 ◽

Chain Reaction ◽

Diagnostic Challenge ◽

Cancer Antigen ◽

Pancreatic Tuberculosis ◽

Peritoneal Biopsy ◽

Polymerase Chain ◽

One Year

Pancreatic tuberculosis (TB) is an uncommon form of extrapulmonary TB and represents a diagnostic challenge for physicians. Pancreatic TB presents with nonspecific signs and symptoms and may mimic malignancy. However, pancreatic TB rarely occurs in children. Here, we present a case of a 5-year-old girl with pancreatic TB and markedly elevated serum cancer antigen- (CA-) 125 levels, thus raising the suspicion of malignancy, but positivity forMycobacterium tuberculosisDNA was noted. The patient recovered after being administered standard antitubercular therapy for one year. This case suggests that clinicians should have a heightened suspicion of pancreatic TB when faced with pancreatic lesions despite the fact that increased CA-125 may indicate malignancy. Laparoscopy combined with peritoneal biopsy and polymerase chain reaction (PCR) may provide a new method to confirm the diagnosis.

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