scholarly journals Sensitivity of optical coherence tomography and visual evoked potential in demyelinating optic neuritis

2020 ◽  
Vol 113 (3) ◽  
pp. 83
Author(s):  
ShaymaaH Salah ◽  
YoussefA.H Helmy ◽  
EmadA Sawaby ◽  
MohammedA Awadalla
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Neuritis ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Optical Coherence ◽  
Visual Evoked

scholarly journals Visual evoked potential and optical coherence tomography in pseudotumor cerebri

Research ◽  
2015 ◽  
Vol 2 ◽  
Author(s):  
Mualla Hamurcu ◽  
MSinan Sarıcaoğlu ◽  
Semra Koca ◽  
Selcan Ekicier ◽  
Ahmet Karakurt
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Pseudotumor Cerebri ◽  
Optical Coherence ◽  
Visual Evoked

Role of visual evoked potentials and optical coherence tomography in the screening for optic pathway gliomas in patients with neurofibromatosis type I

2020 ◽  
pp. 112067212090698
Author(s):  
Aldo Vagge ◽  
Paola Camicione ◽  
Marco Pellegrini ◽  
Giulia Gatti ◽  
Paolo Capris ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Area Under The Curve ◽  
Neurofibromatosis Type ◽  
Optic Pathway Glioma ◽  
Optic Pathway ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Visual Evoked

Purpose: The purpose of the present study was to compare visual function assessment, visual evoked potential, and optical coherence tomography with measurement of retinal nerve fiber layer thickness for the diagnosis of optic pathway glioma in children with neurofibromatosis type 1. Methods: This retrospective observational study included patients with neurofibromatosis type 1 who underwent brain magnetic resonance imaging scan, visual evoked potential study, and peripapillary retinal nerve fiber layer evaluation by optical coherence tomography. Patients were tested with pattern-reversal visual evoked potential and with flash visual evoked potential in case of poor cooperation. Optical coherence tomography was performed with HRA Spectralis (Heidelberg Engineering, Heidelberg, Germany). The area under the curve of receiver operating characteristic curves was used to evaluate the accuracy of each parameter for diagnosing optic pathway glioma. Results: In all, 110 patients with neurofibromatosis type 1 were included in the study. Fifty of them had an optic pathway glioma diagnosed with magnetic resonance imaging, while 60 did not. Global retinal nerve fiber layer thickness demonstrated the highest diagnostic power for discriminating patients with and without optic pathway glioma (area under the curve = 0.758, sensitivity = 65.3%, specificity = 83.3%), followed visual acuity (area under the curve = 0.723, sensitivity = 51.1%, specificity = 91.7%) and P100 of visual evoked potential (area under the curve = 0.712, sensitivity = 69.6%, specificity = 63.8%). Conclusion: The results of the present study showed that the measurement of retinal nerve fiber layer thickness was the most efficient test for discriminating patients with and without optic pathway glioma. Brain magnetic resonance imaging remains the gold standard to confirm the diagnosis of optic pathway glioma. Longitudinal studies are required to define if the early detection of tumors with optical coherence tomography could prevent vision loss and morbidity.

Early Criteria for the Diagnosis of Optic Neuritis in the Setting of Davic’s Disease

The Eye ◽  
2021 ◽  
Vol 23 (2) ◽  
pp. 33-39
Author(s):  
Kh. M. Kamilov ◽  
M. S. Kasimova ◽  
G. Kh. Khamraeva
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optical Coherence Tomography ◽  
Optic Neuritis ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Brain And Spinal Cord ◽  
The Brain ◽  
Potential Test

Background. Optic neuritis is the first symptom of Davic’s disease in more than half of cases. Differential diagnosis of optic neuritis in the clinical practice is complicated due to the uniformity of the clinical pattern of inflammatory and demyelinating optic neuritis in the early stages of the disease. The approach to the management of patients with Davic’s disease is varied and requires a precise differentiation at the initial stages of its development.Purpose. To determine early objective criteria for diagnosing the optic neuritis in the setting of Davic’s disease.Materials and methods. We observed 31 patients (51 eyes), while the control group consisted of 12 healthy individuals (12 eyes). Research methods were both standard ophthalmic and specialized – optical coherence tomography, visual evoked potential test, magnetic resonance imaging of the brain and spinal cord.Results. In patients with optic neuritis in the setting of Davic’s disease, optical coherence tomography revealed a smaller area of the optic nerve disc and neuroretinal belt as well as a decrease in macular volume and macular thickness. A reduction of the retinal ganglion cell complex and the inner plexiform layer was also revealed.Conclusion. At the initial stages of Davic’s disease, it is necessary to conduct optical coherence tomography of the retina, perform visual evoked potential test as well as magnetic resonance imaging of the brain and spinal cord. Appropriate treatment at an early stage of the disease can reduce the rates of axonal degeneration and optic disc atrophy development.

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