scholarly journals Clinical and radiographic evaluation of autogenous dentin graft and demineralized freeze-dried bone allograft with chorion membrane in the treatment of Grade II and III furcation defects-: A randomized controlled trial

2019 ◽  
Vol 11 (2) ◽  
pp. 83 ◽  
Author(s):  
Suryakanth Malgikar ◽  
GuntakalaVikram Reddy ◽  
Atchuta Abhinav ◽  
Ch Bhagyashree ◽  
PRaja Babu ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Bone Allograft ◽  
Radiographic Evaluation ◽  
Randomized Controlled ◽  
Freeze Dried ◽  
Furcation Defects ◽  
Grade Ii

Nepeta menthoides Boiss. & Buhse freeze-dried aqueous extract versus sertraline in the treatment of major depression: a double blind randomized controlled trial

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
S Kolouri ◽  
A Firoozabadi ◽  
A Salehi ◽  
MM Zarshenas ◽  
SA Dastgheib ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Major Depression ◽  
Aqueous Extract ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled ◽  
Freeze Dried

scholarly journals A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ingvild M. Ulvik ◽  
Terje Sæthre ◽  
Dagmar F. Bunæs ◽  
Stein Atle Lie ◽  
Morten Enersen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Clinical Attachment Level ◽  
Treatment Difference ◽  
Randomized Controlled ◽  
Air Polishing ◽  
Probing Depth ◽  
Furcation Defects ◽  
Supportive Periodontal Therapy ◽  
Attachment Level

Abstract Background Due to complex morphology and limited access, the cleaning of the furcation area is extremely challenging. Therefore, novel therapeutic approaches need to be tested to potentially overcome debridement limitations. The aim of the present prospective 12-month study was to compare clinical and microbiological effects following erythritol air-polishing versus conventional mechanical debridement of furcation defects in a cohort of periodontal maintenance patients. Methods Twenty patients with grade II mandibular molar furcation defects volunteered to enroll in this single-centre, examiner masked, randomized controlled trial. In a split-mouth study design, two furcation sites in each patient were randomly assigned to either receive subgingival debridement using erythritol air-polishing (test) or conventional ultrasonic/curette debridement (control) at baseline, and at 3, 6, 9 and 12 months. Probing depth, clinical attachment level and bleeding on probing were recorded at 3-month intervals. Subgingival microbiological samples obtained at baseline, 6 and 12 months were analyzed using checkerboard DNA–DNA hybridization. Discomfort from treatment was scored at 12 months using a visual analogue scale. The differences between treatments, and time-points, were tested using multilevel analysis (mixed effect models and robust variance estimates). Results A significant reduction in probing depth took place following both treatments (p < 0.001). Control sites experienced a significant mean gain in clinical attachment level of 0.5 mm (± 0.2) (p = 0.004), whereas a non-significant gain of 0.4 mm (± 0.3) was observed at test sites (p = 0.119). At 6 months, a significant between-treatment difference of 0.8 mm (± 0.4) was observed in favor of the control (p = 0.032). No significant between-treatment differences were observed in microbial load or composition. Notably, at 12 months patients experienced significantly less discomfort following air-polishing compared with control (p = 0.001). Conclusions The 12-month observations indicate that erythritol air-polishing and conventional mechanical debridement both support clinical improvements. A significant between-treatment difference in clinical attachment level was, however, detected in favour of control debridement at 6 months. In terms of patient comfort, erythritol air-polishing is superior. Trial Registration: The clinical trial was retrospectively registered in ClinicalTrial.gov with registration NCT04493398 (07/28/2020).

Efficacy of a freeze-dried aqueous extract of Nepeta menthoides Boiss. & Buhse in the treatment of anxiety in patients with depression: A double-blind, randomized, controlled trial

2017 ◽  
Vol 10 ◽  
pp. 17-23 ◽  
Author(s):  
Ali Firoozabadi ◽  
Sepideh Kolouri ◽  
Mohammad M. Zarshenas ◽  
Alireza Salehi ◽  
Seyed Hamdollah Mosavat ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Aqueous Extract ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled ◽  
Freeze Dried
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