Oral submucous fibrosis in North Gujarat: A demographic study

2021 ◽  
Vol 8 (1) ◽  
pp. 9
Author(s):  
Ketan Prajapati ◽  
Jyoti Chawda ◽  
Malvi Thakkar ◽  
Nupur Gajera ◽  
Rohit Thakkar ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Demographic Study ◽  
Submucous Fibrosis ◽  
North Gujarat

scholarly journals Comparative Study of Intralesional Dexamethasone Plus Hyaluronidase & Oral Colchicine in Patients with Oral Submucous Fibrosis

2018 ◽  
Vol 14 (2) ◽  
pp. 60-65
Author(s):  
Ganesh Prasad Neupane ◽  
Maya Rai ◽  
R. S. Rathore ◽  
V. K. Bhargava ◽  
A. K. Mahat ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Study Groups ◽  
T Test ◽  
Significant Difference ◽  
Intralesional Injections ◽  
Submucous Fibrosis ◽  
Larger Sample

Introduction: Oral Submucous Fibrosis (OSMF) is a precancerous condition of the oral mucosa. It is characterized by excessive production of collagen leading to inelasticity of the oral mucosa and atrophic changes of the epithelium.Aim and objective: To evaluate the efficacy of oral Colchicine in comparison to intralesional injections of Dexamethasone plus Hyaluronidase in the management of OSMF patients.Materials and Methods: Fourty patients with OSMF were randomly divided equally into two groups. 20 patients in Dexamethasone group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU in buccal mucosa for a period of 12 weeks. Other 20 patients in Colchicine group received oral Colchicine 0.5 mg tablets twice daily for 12 weeks. Parameters taken in the study were burning sensation, and mouth opening. Descriptive statistics, paired t test and unpaired t test were used for statistical analysis.Results and Conclusions: The pre- and post-treatment differences were found to be statistically significant for both the groups (p<0.001) and for both the treatment outcomes. When the average difference of the treatment outcomes was compared between the two study groups, statistically highly significant difference was noted (p <0.001) only in mouth opening but not in burning sensation.These encouraging results should prompt further clinical trials with Colchicine on a larger sample size to broaden the therapeutic usefulness of the drug in the management of OSMF. JNGMC,  Vol. 14 No. 2 December 2016, Page: 60-65

Localized peripheral autonomous neuropathy and dysfunctional myoepithelial cells: A novel hypothesis for xerostomia in oral submucous fibrosis

2020 ◽  
Vol 144 ◽  
pp. 109998
Author(s):  
Gargi S. Sarode ◽  
Sachin C. Sarode ◽  
Amol Gadbail ◽  
Shailesh Gondivkar ◽  
Shankargouda Patil
Keyword(s):  
Oral Submucous Fibrosis ◽  
Myoepithelial Cells ◽  
Submucous Fibrosis

Development and Validation of a Questionnaire to Evaluate Association of Tobacco Abuse With Oral Submucous Fibrosis

2011 ◽  
Vol 27 (2) ◽  
pp. NP132-NP142 ◽  
Author(s):  
Divya Mehrotra ◽  
Girdhar Gopal Agarwal ◽  
Sumit Kumar ◽  
Anand Shukla ◽  
Akash Asthana
Keyword(s):  
Oral Submucous Fibrosis ◽  
Tobacco Abuse ◽  
Submucous Fibrosis ◽  
Development And Validation

scholarly journals Conspicuous and frank dilated vascular spaces: A marker of malignant transformation in oral submucous fibrosis

2021 ◽  
Vol 11 (3) ◽  
pp. 365-367
Author(s):  
Sachin C. Sarode ◽  
Gargi S. Sarode ◽  
Namrata Sengupta ◽  
Urmi Ghone ◽  
Shankargouda Patil
Keyword(s):  
Malignant Transformation ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis
Sign in / Sign up

Export Citation Format

Share Document