scholarly journals A case of personalized limb salvage of the distal femur by three-stage distal femoral replacement

2020 ◽  
Vol 6 (1) ◽  
pp. 81
Author(s):  
Androniki Drakou ◽  
Konstantinos Zygogiannis ◽  
Markos Psifis ◽  
Aristides Mitrou
2014 ◽  
Vol 20 (1) ◽  
pp. 36
Author(s):  
Jong Hoon Park ◽  
Si-Young Park ◽  
Dae Hee Lee ◽  
Yeok Gu Hwang ◽  
Hyun Min Lee

Author(s):  
Chiao Yee Lim ◽  
Hirohisa Katagiri ◽  
Hideki Murata ◽  
Junji Wasa ◽  
Michihito Miyagi ◽  
...  

Biomedika ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 90-95
Author(s):  
Muhammad Riyadli ◽  
Mujaddid Idulhaq ◽  
Pamudji Utomo

Giant cell tumor (GCT) with Human Immunodeficiency Virus (HIV) infection is a rare case. At present, few literatures reported about GCT with HIV positive patients and there are no effective treatments of this disease currently. The aim of this article is to report the change the surgical treatment from limb salvage (wide excision and endoprostheses) to another way limb salvage (wide excision and knee arthrodesis) to minimize risk and further complication. A case of male, 25 years old, with diagnosis GCT of the right distal femur with HIV positive. In this case we administered antiretroviral treatment (ARV) and planned to limb salvage surgery (wide excision and knee arthrodesis).We follow up this patient in the first 4 weeks. There were no complaints, good postoperative wounds, no signs of infection, and histopathological examination postoperative showed the positive results of a GCT. The conclusion the surgical treatment from limb salvage (wide excision and endoprostheses) to another way limb salvage (wide excision and knee arthrodesis) could minimize risk and further complication.Keywords: Giant Cell Tumor, HIV,Limb Salvage Surgery, Wide Excision, Arthrodesis KneeGiant Cell Tumor (GCT) disertai dengan infeksi Human Imminodeficiency Virus (HIV) merupakan kasus yang jarang terjadi. Pada saat ini hanya sedikit literatur yang melaporkan kejadian pasien GCT dengan HIV positif dan belum ada standar terapi yang efektif. Tujuan dari artikel ini adalah melaporkan penggantian penatalaksanaan operatif sebelumnya berupa limb salvage (eksisi luas dan pemasangan endoprosthesis) menjadi eksisi luas dan arthrodesis knee untuk meminimalisir risiko dan kompikasi lebih lanjut. Kasus seorang laki-laki usia 25 tahun dengan diagnosis GCT pada distal femur kanan dengan infeksi HIV positif. Pada kasus ini, terapi yang diberikan adalah Anti Retroviral (ARV) dan operatif dengan limb salvage (eksisi luas dan arthrodesis lutut). Follow up pasien ini pada 4 minggu pertama post operasi. Keluhan nyeri berkurang, luka operasi baik, tidak ada tanda infeksi dan pemeriksaan histopatologi menunjukkan hasil GCT.Kesimpulannya bahwa penatalaksanaan operatif sebelumnya berupa limb salvage (eksisi luas dan pemasangan endoprosthesis) menjadi eksisi luas dan arthrodesis knee dapat meminimalisir risiko dan kompikasi lebih lanjut. Kata Kunci: Giant Cell Tumor, Hiv, Limb Salvage, Eksisiluas, Arthrodesis Lutut


2020 ◽  
Vol 35 (5) ◽  
pp. 1402-1406 ◽  
Author(s):  
Brian Darrith ◽  
Daniel D. Bohl ◽  
Mark S. Karadsheh ◽  
Scott M. Sporer ◽  
Richard A. Berger ◽  
...  

Sarcoma ◽  
2004 ◽  
Vol 8 (1) ◽  
pp. 47-49 ◽  
Author(s):  
Robert S. Lee ◽  
Deborah Higgs ◽  
Omar Haddo ◽  
Jean Pringle ◽  
Timothy W. R. Briggs

Purpose: Diamond–Blackfan anaemia (DBA) is a rare pure congenital red cell aplasia, usually presenting in infancy or early childhood. The literature suggests a predisposition to haemopoietic malignancy but in addition solid tumours have been reported, with five cases of osteosarcoma described.Patient: A sixth case of a 12-year-old girl with DBA who developed an osteosarcoma of the distal femur is presented.Results: She was treated with methotrexate followed by tumour excision and distal femoral replacement. The patient is currently alive with multiple pulmonary metastases.Discussion: We discuss the association between the administration of growth hormone and future development of malignancy in patients with DBA.


Injury ◽  
2018 ◽  
Vol 49 (2) ◽  
pp. 392-397 ◽  
Author(s):  
Jason S. Hoellwarth ◽  
Mitchell S. Fourman ◽  
Lawrence Crossett ◽  
Mark Goodman ◽  
Peter Siska ◽  
...  

Author(s):  
Meagan E. Tibbo ◽  
Joshua A. Parry ◽  
Mario Hevesi ◽  
Matthew P. Abdel ◽  
Brandon J. Yuan

2020 ◽  
Author(s):  
Tao Cai ◽  
Chunlin Zhang ◽  
Lei Zhang ◽  
Kunpeng Zhu ◽  
Jianping Hu ◽  
...  

Abstract Purpose The purpose of this study was to introduce the surgical technique and functional outcome of joint-sparing limb salvage surgery with metaphyseal osteotomy by dependent design of three-dimensional printed prothesis for children with osteosarcoma in distal femur.Methods Between 2012 to 2019, we performed twelve joint sparing limb salvage surgeries (JSLSS) with metaphyseal osteotomy for the children of osteosarcoma in the distal femur with our dependent design of 3D-printed guided plate and prothesis. The clinical assessment including resection margin, limb-length discrepancy, orthopaedic complications and functional outcome would be analyzed.Results The mean operation time for JSLSS was 107.6 minutes and the average blood loss was 194.5ml with the dependent design of 3D-printed prosthesis. With the assistance of guide plate, the mean margin of the osteosarcoma from the epiphyseal plate was 1.6 cm and the mean limb-length discrepancy was 2.2 cm with maximum follow-up period of seven years (mean 45.3 months, range 12-84 months). All the patients could bend their knee through >90° flexion, achieved similar results for ROMs in 6DOF during gait compared with normal data of Chinese knees, and the mean MSTS score was 94.7 for the patients with JSLSS. One patient had a superficial infection and there was one patient of local recurrence happened during the follow-up with the necrosis rate less than 90% by preoperative chemotherapy. None aseptic loosening happened in distal femur for the patients in this group with dependent design of 3D-printed prosthesis.Conclusion Joint-sparing limb salvage surgery by metaphyseal osteotomy with the dependent design of 3D-printed prosthesis and guide plate would be a good choice for the children with osteosarcoma in distal femur.


2020 ◽  
Author(s):  
Tao Cai ◽  
Chunlin Zhang ◽  
Lei Zhang ◽  
Kunpeng Zhu ◽  
Jianping Hu ◽  
...  

Abstract Purpose The purpose of this study was to introduce the surgical technique and functional outcome of joint-sparing limb salvage surgery with metaphyseal osteotomy by dependent design of three-dimensional printed prothesis for children with osteosarcoma in distal femur.Methods Between 2012 to 2019, we performed twelve joint sparing limb salvage surgeries (JSLSS) with metaphyseal osteotomy for the children of osteosarcoma in the distal femur with our dependent design of 3D-printed guided plate and prothesis. The clinical assessment including resection margin, limb-length discrepancy, orthopaedic complications and functional outcome would be analyzed.Results The mean operation time for JSLSS was 107.6 minutes and the average blood loss was 194.5ml with the dependent design of 3D-printed prosthesis. With the assistance of guide plate, the mean margin of the osteosarcoma from the epiphyseal plate was 1.6 cm and the mean limb-length discrepancy was 2.2 cm with maximum follow-up period of seven years (mean 45.3 months, range 12-84 months). All the patients could bend their knee through >90° flexion, achieved similar results for ROMs in 6DOF during gait compared with normal data of Chinese knees, and the mean MSTS score was 94.7 for the patients with JSLSS. One patient had a superficial infection and there was one patient of local recurrence happened during the follow-up with the necrosis rate less than 90% by preoperative chemotherapy. None aseptic loosening happened in distal femur for the patients in this group with dependent design of 3D-printed prosthesis.Conclusion Joint-sparing limb salvage surgery by metaphyseal osteotomy with the dependent design of 3D-printed prosthesis and guide plate would be a good choice for the children with osteosarcoma in distal femur.


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