Anticoagulation in pregnant women with mechanical heart valve prostheses: Case reports and a literature review

2021 ◽  
Vol 28 (1) ◽  
pp. 68
Author(s):  
PhilipAlaba Adebola ◽  
FolasadeA Daniel ◽  
YusufA Oshodi ◽  
Abidoye Gbadegesin ◽  
OlagokeK Ale ◽  
...  
2000 ◽  
Vol 55 (2) ◽  
pp. 72
Author(s):  
S. S. Meschengieser ◽  
C. G. Fondevila ◽  
M. T. Santarelli ◽  
M. A. Lazzari

Heart ◽  
1999 ◽  
Vol 82 (1) ◽  
pp. 23-26 ◽  
Author(s):  
S S Meschengieser ◽  
C G Fondevila ◽  
M T Santarelli ◽  
M A Lazzari

2002 ◽  
Vol 35 (10) ◽  
pp. 1427-1432 ◽  
Author(s):  
G.B Fiore ◽  
M Grigioni ◽  
C Daniele ◽  
G D’Avenio ◽  
V Barbaro ◽  
...  

2018 ◽  
Vol 03 (02/03) ◽  
pp. 189-192
Author(s):  
Chaitanya Nelavayi ◽  
Kumar Achukatla ◽  
Bhanu Badhvel ◽  
Sree Gurram ◽  
Vanajakshamma Velam ◽  
...  

Abstract Objective To study the effect of nicoumalone on embryogenesis in women who have undergone mechanical heart valve replacement surgery. Design It is a retrospective study done at Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati. Results Total 28 pregnancies were reported in 12 women with mechanical heart valve prostheses. Of these, 19 were live births, 9 abortions, and no stillbirths and miscarriages were noted in pregnant women. There were 11 hemorrhagic, 3 neurologic, 2 thromboembolic, and 1 stuck valve complications observed in mothers; and 2 low birth weights, 2 pneumonia, and 1 jaundice observed in the child. Conclusion There were no abnormalities observed in children whose mothers were taking nicoumalone throughout pregnancy based on echo results and clinical examination.


1992 ◽  
Vol 15 (11) ◽  
pp. 681-685 ◽  
Author(s):  
M.O. Wendt ◽  
M. Pohl ◽  
S. Pratsch ◽  
D. Lerche

Hemolytic and subhemolytic blood damage by mechanical heart valve prostheses have been observed in both clinical and in vitro investigations. A direct comparison between these studies is not possible. Nevertheless the transfer of some in vitro results to the behaviour of the valve in situ may be performed considering the similarity principle. This requires the use of dimensionless similarity numbers such as the plasma's hemoglobin concentration (PHb) or others, instead of dimensioned parameters. To evaluate the in vitro hemolysis of valve prosthesis a test chamber filled with human banked blood was used. An artificial ventricle ensuring an oscillatory flow through the valve was also used. The rise of PHb was evaluated in terms of a similarity number, called the lysis number. This number describes the probability of destroying a single red blood cell participating once in the hemolytic process under consideration. The lysis number, a Björk-Shiley valve (TAD 29), was found to be in the order of 2 × 10−4. From this, the survival time of erythrocytes in patients with an artificial heart valve was estimated. It was found to be in the order of 20 d of T50 Cr in agreement with clinical results


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