Transcranial Doppler to detect early abnormalities in cerebral hemodynamics following traumatic brain injury in adult patients

2020 ◽  
Vol 7 (3) ◽  
pp. 274
Author(s):  
AmaniA Aly ◽  
ManalS Farmawy
2013 ◽  
Vol 71 (10) ◽  
pp. 802-806 ◽  
Author(s):  
Almir Ferreira de Andrade ◽  
Matheus Schmidt Soares ◽  
Gustavo Cartaxo Patriota ◽  
Alessandro Rodrigo Belon ◽  
Wellingson Silva Paiva ◽  
...  

Objective Intracranial hypertension (IH) develops in approximately 50% of all patients with severe traumatic brain injury (TBI). Therefore, it is very important to identify a suitable animal model to study and understand the pathophysiology of refractory IH to develop effective treatments. Methods We describe a new experimental porcine model designed to simulate expansive brain hematoma causing IH. Under anesthesia, IH was simulated with a balloon insufflation. The IH variables were measured with intracranial pressure (ICP) parenchymal monitoring, epidural, cerebral oximetry, and transcranial Doppler (TCD). Results None of the animals died during the experiment. The ICP epidural showed a slower rise compared with parenchymal ICP. We found a correlation between ICP and cerebral oximetry. Conclusion The model described here seems useful to understand some of the pathophysiological characteristics of acute IH.


PM&R ◽  
2015 ◽  
Vol 7 ◽  
pp. S103-S103 ◽  
Author(s):  
Michael W. O'Dell ◽  
Heather W. Walker ◽  
Steven R. Edgley ◽  
Jean-Michel Gracies ◽  
Fatma Gul ◽  
...  

Toxicon ◽  
2016 ◽  
Vol 123 ◽  
pp. S35 ◽  
Author(s):  
Jean-Michel Gracies ◽  
Allison Brashear ◽  
Christina Marciniak ◽  
Robert Jech ◽  
Marta Banach ◽  
...  

Toxicon ◽  
2016 ◽  
Vol 123 ◽  
pp. S34
Author(s):  
Jean-Michel Gracies ◽  
Allison Brashear ◽  
Alberto Esquenazi ◽  
Michael O'Dell ◽  
Thierry Deltombe ◽  
...  

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