scholarly journals Antiphospholipid Antibody Syndrome Associated with Graves' Disease Presenting as Inferior Vena Cava Thrombosis with Bilateral Lower Limb DVT

2014 ◽  
Vol 7 ◽  
pp. CCRep.S15302 ◽  
Author(s):  
Ankur Jain
Keyword(s):  
Inferior Vena Cava ◽  
Lower Limb ◽  
Inferior Vena ◽  
Case Reports ◽  
Vena Cava ◽  
Antithyroid Drugs ◽  
Graves Disease ◽  
Antiphospholipid Antibody ◽  
Antiphospholipid Antibody Syndrome ◽  
Bilateral Lower Limb

We report a case of a 60-year-old lady who presented with bilateral lower limb swelling and a thyroid swelling with clinical features consistent with thyrotoxicosis. Investigations revealed the presence of a thrombus in bilateral external, internal iliac veins, and inferior vena cava extending up to its infrahepatic part. Hormone profile and radioiodine uptake scan confirmed the diagnosis of Graves' disease. Further workup revealed the presence of antiphospholipid antibodies (confirmed after a repeat test at 12 weeks). The patient was treated with antithyroid drugs and anticoagulants. The patient improved with normalization of thyroid function and partial recanalization of the infrahepatic part of inferior vena cava. Hyperthyroidism has been implicated as a potential hypercoagulable state; however, the association of Graves' disease with antiphospholipid antibody syndrome is limited to isolated case reports. This case highlights a new mechanism underlying hypercoagulability associated with Graves' disease.

scholarly journals Bilateral Lower Limb Edema Caused by Compression of the Retrohepatic Inferior Vena Cava by a Giant Hepatic Hemangioma

2013 ◽  
Vol 98 (3) ◽  
pp. 229-233 ◽  
Author(s):  
Sami Akbulut ◽  
Mehmet Yilmaz ◽  
Aysegul Kahraman ◽  
Sezai Yilmaz
Keyword(s):  
Inferior Vena Cava ◽  
Lower Limb ◽  
Inferior Vena ◽  
Vena Cava ◽  
Hepatic Hemangioma ◽  
Limb Edema ◽  
Bilateral Lower Limb ◽  
Right Lobe ◽  
The Right ◽  
Giant Hepatic Hemangioma

Abstract Hemangiomas are the most common benign primary tumors of the liver and their prevalence ranges from 0.4% to 20%. Approximately 85% of hemangiomas are clinically asymptomatic and are incidentally detected in imaging studies performed for other causes. In a very small minority of patients, nausea, vomiting, abdominal pain, distension, palpable mass, obstructive jaundice, bleeding, and signs and symptoms of Budd-Chiari syndrome may develop due to compression of bile duct, hepatic vein, portal vein, and adjacent organs. Occasionally, external compression of inferior vena cava may lead to edema and/or indirect symptoms such as deep vein thrombosis of the lower limbs. In this report, we present a case of giant hepatic hemangioma that completely filled the right lobe of the liver. The patient presented with bilateral lower limb edema and pain. A computed tomography scan detected a 9 × 11 × 12 cm mass indicative of a hemangioma in the right lobe of the liver that compressed the inferior vena cava. The patient refused treatment initially but returned 6 months later presenting with the same symptoms. At that time, the mass had increased in size and a hepatectomy was performed, preserving the middle hepatic vein. By postoperative month 13, the swelling in the lower extremities had decreased significantly and the inferior vena cava appeared normal.

scholarly journals Thrombotic storm in a 4-year-old boy with a thrombus in the right atrium

2018 ◽  
Vol 32 ◽  
pp. 205873841877812 ◽  
Author(s):  
Jing-Yao Ma ◽  
Xin Zhang ◽  
Xiao-Feng Li ◽  
Le-Jian He ◽  
Ning Ma ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Anticoagulant Therapy ◽  
Right Atrium ◽  
Inferior Vena ◽  
Vena Cava ◽  
Pathological Examination ◽  
Antiphospholipid Antibody ◽  
Antiphospholipid Antibody Syndrome ◽  
Tumor Embolus ◽  
Embolism And Thrombosis

Thrombotic storm (TS) is a rare disease, especially with thrombus in the heart of pediatric patient. We present a case of a 4-year-old boy, who was diagnosed with TS during his first hospitalization due to lower extremity deep venous thrombosis, pulmonary embolism, and thrombosis of the inferior vena cava, cerebral, left internal jugular, portal, renal, and iliac veins. He was eventually prescribed with rivaroxaban to control thrombosis after 30 days of successive use of low-molecular-weight heparin, unfractionated heparin, and warfarin, which were demonstrating little effect on preventing thrombosis, and the patient was intolerant to argatroban. While his lupus anticoagulant ratio was slightly above the normal range and no other potential causes such as congenital thrombophilia, severe infection, malignancy, and trauma were confirmed, we suspected antiphospholipid antibody syndrome and prescribed glucocorticoid and rituximab to control the disease. After 36 days of admission, ultrasonography showed recanalization of the former thrombus. One month after discharge, a tumor embolus resembling a mass emerged in his right atrium under effective anticoagulant therapy. During his second admission, he underwent surgical thrombectomy, and pathological examination confirmed the mass to be a platelet-rich thrombus rather than tumor embolus or infection. Considering the suspected antiphospholipid antibody syndrome as the cause of the TS, we prescribed aspirin combined with rivaroxaban to prevent thrombosis. In this case, surgery and pathology shed light on the type of thrombus that emerged from the inferior vena cava and traveled to the heart, which is the possible potential cause of TS. It also changed our therapeutic strategy to antiplatelet therapy combined with anticoagulant therapy to control the disease.

Tips and tricks for retrieval of permanent TRAPEASE® filters for inferior vena cava

Vascular ◽  
2014 ◽  
Vol 23 (6) ◽  
pp. 648-652 ◽  
Author(s):  
Albeir Y Mousa ◽  
Shadi AbuHalimah ◽  
Michael Yacoub ◽  
Iqra Sheikh ◽  
Ali F AbuRahma
Keyword(s):  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Case Reports ◽  
Vena Cava ◽  
Tips And Tricks ◽  
Inferior Vena Cava Filters ◽  
Vena Cava Filters

The placement of permanent inferior vena cava filters has definite indications and some filters have been shown to be more problematic in the long term than others. This report outlines the technique for TRAPEASE® filter removal in two patients. The first filter was retrieved four weeks after insertion and the second filter was retrieved 14 months after it was inserted at another institution. A planned approach for retrieval is described in these case reports.

scholarly journals Case reports of robot-assisted laparoscopic radical nephrectomy and inferior vena cava tumor thrombectomy

Medicine ◽  
2021 ◽  
Vol 100 (33) ◽  
pp. e26886
Author(s):  
Shuaijun Ma ◽  
Weijing Jia ◽  
Guangdong Hou ◽  
Penghe Quan ◽  
Longlong Zhang ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Radical Nephrectomy ◽  
Inferior Vena ◽  
Case Reports ◽  
Vena Cava ◽  
Robot Assisted ◽  
Laparoscopic Radical Nephrectomy

Ovarian Vein Thrombosis Extending to Inferior Vena Cava in Postpartum Period: Case Reports and Literature Review

Flebologiia ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 244
Author(s):  
I.S. Lebedev ◽  
D.A. Son ◽  
D.A. Churikov ◽  
O.I. Efremova ◽  
S.M. Yumin ◽  
...  
Keyword(s):  
Literature Review ◽  
Inferior Vena Cava ◽  
Postpartum Period ◽  
Inferior Vena ◽  
Case Reports ◽  
Vena Cava ◽  
Ovarian Vein ◽  
Vein Thrombosis ◽  
Ovarian Vein Thrombosis
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