Quantitative determination of erlotinib andO-desmethyl erlotinib in human EDTA plasma and lung tumor tissue

Bioanalysis ◽  
2012 ◽  
Vol 4 (21) ◽  
pp. 2563-2577 ◽  
Author(s):  
NAG Lankheet ◽  
EE Schaake ◽  
H Rosing ◽  
JA Burgers ◽  
JHM Schellens ◽  
...  
Planta Medica ◽  
2011 ◽  
Vol 78 (03) ◽  
pp. 252-259 ◽  
Author(s):  
Li Li ◽  
Jinhui Zhang ◽  
Ahmad Shaik ◽  
Yong Zhang ◽  
Lei Wang ◽  
...  

2013 ◽  
Vol 35 ◽  
pp. 465-474 ◽  
Author(s):  
Julie Doucet ◽  
An Zhao ◽  
Jean Fu ◽  
Alexandre Avrameas

A novel sandwich ELISA for the quantitative and sensitive determination of IL-13 in human serum and plasma was established. The assay employs an incubation step at acidic pH, which was shown to decrease nonspecific binding and interference from IL-13 binding proteins. The assay was validated and was shown to be accurate and precise over the entire quantification range (0.59 to 68.4 pg/mL in human EDTA plasma). The validated assay was successfully applied to samples from healthy volunteers and patients with atopic seasonal rhinitis. The assay is suitable for use in clinical trials to monitor efficacy or pharmacodynamic effects of drug candidates.


1999 ◽  
Vol 96 (9/10) ◽  
pp. 1608-1615
Author(s):  
T. E. Malliavin ◽  
H. Desvaux ◽  
M. A. Delsuc

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
M Koşar ◽  
F Göger ◽  
N Kırımer ◽  
KHC Başer

Planta Medica ◽  
2013 ◽  
Vol 79 (05) ◽  
Author(s):  
YH Wang ◽  
C Avonto ◽  
B Avula ◽  
M Wang ◽  
TJ Smillie ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
FHA Fernandes ◽  
RSA Batista ◽  
G Véras ◽  
FS Souza ◽  
ACD Medeiros

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
YH Wang ◽  
S Hu ◽  
B Avula ◽  
M Wang ◽  
S Sagi ◽  
...  

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