Nanoparticulate drug delivery systems for modified tissue distribution and better cancer chemotherapy

2015 ◽  
Vol 06 (01) ◽  
Author(s):  
R N Saha
Author(s):  
Mahsa Mazdaei ◽  
Kofi Asare-Addo

The application of nanotechnology indrug delivery systems (DDS) has been researched widely and seen an advancementover the past three decades. Since the 1970s, nanoparticles were primarilyutilised in vaccine deliveries and cancer chemotherapy. In more recent years,they have been found to hold promises for broader applications such as inproteins and therapeutic gene delivery systems. To date, there have been only ahandful of nanocarrier-loaded drugs commercialised into the pharmaceuticalmarket. More research is thus needed to facilitate a breakthrough of theseproducts into the current market. This mini-review mainly focuses on four typesof commonly utilised organic nanocarriers including micelles, compactpolymerics, solid-lipid nanoparticles and liposomal vesicles and discusses theprogress and some challenges associated with these nanoparticles (NP). 


Drug Delivery ◽  
2010 ◽  
Vol 17 (6) ◽  
pp. 365-375 ◽  
Author(s):  
Raquel De Souza ◽  
Payam Zahedi ◽  
Christine J. Allen ◽  
Micheline Piquette-Miller

2010 ◽  
Vol 27 (7) ◽  
pp. 215-231 ◽  
Author(s):  
Ranendra N. Saha ◽  
Sekar Vasanthakumar ◽  
Girish Bende ◽  
Movva Snehalatha

2021 ◽  
Vol 36 (1) ◽  
pp. 40-50
Author(s):  
Makiya Nishikawa ◽  
Yukitake Yoshioka ◽  
Makoto Nagaoka ◽  
Kosuke Kusamori

2017 ◽  
Vol 5 (4) ◽  
pp. 661-670 ◽  
Author(s):  
Xun Liu ◽  
Qian Huang ◽  
Caixia Yang ◽  
Qianzhi Zhang ◽  
Wan Chen ◽  
...  

Modification of drug delivery systems (DDSs) with stimuli-responsive elements could significantly increase the tumor-specific delivery of anticancer drugs.


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