This article reports on the results of replacement arthroplasty in the treatment of bone chondrosarcoma. As a result of replacement arthroplasty in 28 patients, post-surgical complications were observed in two (7.1 %) patients, and tumor recurrence was observed in two (7.1 %) patients. Infectious post-surgical complications were observed in one patient after replacement arthroplasty of coxofemoral joint; the endoprosthesis in this patient was removed, and cement spacer was implanted; six months later the replacement arthroplasty was repeated. The aseptic loosening of the endoprosthetic stem of the joint was observed in one patient after knee arthroplasty; the replacement arthroplasty was repeated. The chondrosarcoma recurrence was identified in two patients between 18 to 53 months; lower extremity amputation was performed in one patient at the level of the mid-third of the femur; lower extremity amputation was performed in one patient at the level of the lower third of the femur, and polychemotherapy courses, including further metastasectomy, were performed in three patients having dedifferentiated and mesenchymal chondrosarcoma with metastases in the lungs. The functional result in the extremity, depending on the tumor site (based on MSTS scoring system) after the endoprosthetic procedure constituted 68.4 to 89.2 %. The quality of life of patients, according to the EORTC QLQ-30 questionnaire, was 40–50 scores before the arthroplasty, while after the arthroplasty the score went up and constituted 85–90 on average. The overall three-year survival rate of patients with chondrosarcoma constituted 95.3 ± 1.7 % and the five-year survival rate was 89.7 ± 2.1 %. The survival rate for patients with mesenchymal and dedifferentiated chondrosarcoma constituted 0 %.
Health-Related Quality of Life after Major Lower Extremity Amputation Due to Musculoskeletal Tumors
