scholarly journals Synthesis and Antibacterial Activity of Urea and Thiourea Derivatives of Anacardic Acid Mixture Isolated from A Natural Product Cashew Nut Shell Liquid (CNSL)

2012 ◽  
Vol 02 (03) ◽  
pp. 267-275 ◽  
Author(s):  
N. Subhakara Reddy ◽  
A. Srinivas Rao ◽  
M. Adharvana Chari ◽  
V. Ravi kumar ◽  
V. Jyothy ◽  
...  
2012 ◽  
Vol 9 (4) ◽  
pp. 287-293 ◽  
Author(s):  
N. Subhakara Reddy ◽  
A. Srinivas Rao ◽  
M. Adharvana Chari ◽  
V. Ravi kumar ◽  
V. Jyothy ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Aracelli de Sousa Leite ◽  
Alisson Ferreira Dantas ◽  
George Laylson da Silva Oliveira ◽  
Antonio L. Gomes Júnior ◽  
Sidney Gonçalo de Lima ◽  
...  

The cashew nut releases a substance that is known as cashew nut shell liquid (CNSL). There are both natural (iCNSL) and technical (tCNSL) cashew nut shell liquids. This study used anArtemia salinabioassay to evaluate the toxic effects of iCNSL and tCNSL cashew nut shell liquids. It also evaluated the toxicity, cytotoxicity, and mutagenicity of CNSL and its effects on the damage induced by copper sulfate (CuSO4·5H2O) on the meristems’ root ofAllium cepa. Effects of the damage induced by CuSO4·5H2O were evaluated before (pre-), during (co-), and after (post-) treatments. The iCNSL contained 94.5% anacardic acid, and the tCNSL contained 91.3% cardanol. The liquids were toxic toA. salina. Toxicity, cytotoxicity, and mutagenicity were observed with iCNSL compared with the negative control. Similarly, iCNSL failed to inhibit the toxicity and cytotoxicity of CuSO4·5H2O. The tCNSL was not toxic, cytotoxic, or mutagenic in any of the concentrations. However, the lowest iCNSL concentrations and all of the tCNSL concentrations had preventive, antimutagenic, and reparative effects on micronuclei and on chromosomal aberrations in theA. cepa. Therefore, protective, modulating, and reparative effects may be observed in theA. cepa, depending on the concentration and type of CNSL used.


2017 ◽  
Vol 10 (4) ◽  
pp. 31 ◽  
Author(s):  
Selene Morais ◽  
Katherine Silva ◽  
Halisson Araujo ◽  
Icaro Vieira ◽  
Daniela Alves ◽  
...  

2013 ◽  
Vol 54 (2) ◽  
pp. 196-202 ◽  
Author(s):  
Palanivel Velmurugan ◽  
Mahudunan Iydroose ◽  
Sang-Myung Lee ◽  
Min Cho ◽  
Jung-Hee Park ◽  
...  

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 407-408
Author(s):  
Venício M Carvalho ◽  
Vicente A Diaz Avila ◽  
Aylle Medeiros Matos ◽  
Edineia Bonin ◽  
Amanda T Teixeira Mendes ◽  
...  

Abstract This work was carried out to evaluate in vitro antimicrobial activity of cashew nut shell liquid (CNSL) and clove essential oil (Eugenia caryophyllata) on Prevotella albensis (DSM 11370), Prevotella bryantii (DSM 11371) and Prevotella ruminicola (ATCC® 19189™). The experiments were designed using each bacterium exposed to two different doses (1:500 and 1:5000 g/L on Tween) of either clove oil or CNSL and with six replicates. Bacteria were cultivated on Hobson’s M2 medium in Hungate tubes. Cultures without addition of any oils were considered as control. Antimicrobial activity was evaluated using Spectrophotometer Evolution 201 UV-visible (Thermo Scientific) at 600 nm. Readings were performed at 0, 8, 12 and 24 hours after inoculation. Data were analysed using linear mixed models and NLME Procedure in R software. Both clove oil and CNSL had an inhibitory effect against the tested bacteria. However, each bacterium responded differently to the treatment. Clove oil decreased (P < 0.05) the microbial growth of P. ruminicola (-32% and -31%) when doses 1:500 and 1:5000 were used. However, there was no effect of clove oil P. bryantii and P. albensis. The use of CNSL reduced growth of P. albensis (-38 and -41%), P. bryantii (-44% and 52%) and P. ruminicola (-41 and -52%), when doses 1:500 and 1:5000, respectively. These results demonstrate the effect of clove oils and CNSL to inhibit growth of gram negative ruminal bacteria. These results provide a prospect of the use of both products to modulate the rumen. For example, the Prevotellaceae family is responsible to degrade protein, amino acid deamination and formation of volatile fatty acids in the rumen. Thus, CNSL and clove oils have potential to modulate the ruminal fermentation by having antibacterial activity against gram negative bacteria.


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