scholarly journals Prevalence of Congenital Heart Disease and Pulmonary Hypertension in Down's Syndrome: An Echocardiographic Study

2015 ◽  
Vol 23 (2) ◽  
pp. 72 ◽  
Author(s):  
Nilda Espinola-Zavaleta ◽  
María Elena Soto ◽  
Angel Romero-Gonzalez ◽  
Lidia del Carmen Gómez-Puente ◽  
Luis Muñoz-Castellanos ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Congenital Heart ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Echocardiographic Study

scholarly journals Down’s Syndrome with Congenital Heart Disease: Our Surgical Experience

2020 ◽  
Vol 13 (1) ◽  
pp. 35-39
Author(s):  
Md Zahidul Islam ◽  
Sakila Israt Jahan ◽  
Shahriar Moinuddin ◽  
Khondokar Shamim Shahriar Ziban Rushel ◽  
Shafiqul Islam ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Pulmonary Hypertension ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Surgical Correction ◽  
Pace Maker

Background: Our objective was to analyze the outcome of patients of Down’s syndrome with congenital heart diseases undergoing cardiac surgery. Methods: This was a retrospective study conducted between January 2013 and June 2019. 49 consecutive patients with Down’s syndrome with congenital heart disease admitted in pediatric cardiac surgery unit at National Institute of Cardiovascular Diseases (NICVD). Patients were followed up postoperatively for in-hospital outcome. Results: Among 49 patients the heart lesion ranked in incidence as follows- VSD 24(48.97%), AV canal defect 12(24.48%), TOF 6(12.24%), PDA 6(12.24%) and ASD 1(2.04%). Pulmonary hypertension was found in 63.25% patients. Moderate pulmonary hypertension was most common, found in 18(38.66%) patients. Severe and mild pulmonary hypertension was found in 10(32.38%) and 3(9.67%) patients respectively. All the patients had undergone surgical correction. The postoperative period was complicated in 44.89% of patients. The most frequent complication was pulmonary infection 20.40%, Wound infection 6.12% and low output syndrome 6.12% were the next. One patient had postoperative heart block, needed permanent pace maker implantation. In-hospital mortality was 12.24%. Conclusion: Patients with Down’s syndrome with congenital heart disease undergoing surgical correction had an acceptable postoperative morbidities and mortality. Cardiovasc. j. 2020; 13(1): 35-39

scholarly journals Down's Syndrome with Congenital Heart Disease: Analysis of Cases Over Two Years in a Non-Invasive Laboratory of a Tertiary Hospital

1970 ◽  
Vol 2 (2) ◽  
pp. 184-187
Author(s):  
NN Fatema
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Doppler Echocardiography ◽  
Congenital Heart ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Tertiary Hospital ◽  
Study Group ◽  
Non Invasive ◽  
Study Results

Background: Trisomy 21 or Down's Syndrome is the most frequent chromosomal aberration affecting live birth infants with an incidence of 1 in 660 live births. This syndrome is often associated with congenital cardiac lesions, Incidence of which is 40-60 percent. This study was conducted to see the frequency of Down’s syndrome cases and pattern of heart diseases they have in one of the busy non-invasive pediatric cardiac laboratory of the country. Methods: It was a retrospective study conducted in the non-invasive pediatric cardiac laboratory and pediatric cardiac outpatient clinic of a tertiary hospital over a period of two years (November 2007 to October 2009). The entire patients who had Down's Syndrome and had Doppler echocardiography were included in the study. Results: Out of total six thousand and fifty echocardiography, Down's Syndrome case was 205 (3.38%). Out of 205 cases, 185 cases were followed up in pediatric cardiac out patient clinic. Twenty cases had not reported in the out patient clinic. Seventeen of those patients had normal cardiac anatomy in Doppler echocardiography. Male were 43.90% and female were 56.09% amongst study group. Most of the patients are young infant (47.32%). Only 2.44% are in more than 10 years age group. Murmur was audible in 86.49% cases in study group and developmental delay was present in 100% of the cases. Doppler Echocardiography was found as most sensitive and specific investigation for detecting congenital heart disease. A-V canal defect was the commonest association (15.60%). Congenital heart disease was not detected in 8.29% cases. Surgical treatment was advised in 52.19% cases, Device closure was advised in 16.59% cases, medical management was advised in 21.46% cases. Conclusion: Down's syndrome is a very common chromosomal anomaly in our country. Incidence of this syndrome is increasing as number of working women, late marriage and elderly mother increasing. So, multidisciplinary approach for managing this disease should be adopted immediately. Keywords: Down's syndrome; Congenital heart disease. DOI: 10.3329/cardio.v2i2.6637Cardiovasc. j. 2010; 2(2) : 184-187

scholarly journals Supraglottic foreign body in a woman with Down's syndrome and congenital heart disease

Medicine ◽  
2021 ◽  
Vol 100 (14) ◽  
pp. e25455
Author(s):  
Yuchao Liu ◽  
Zijia Liu ◽  
Yang Zha ◽  
Xuerong Yu
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Foreign Body ◽  
Congenital Heart ◽  
Down's Syndrome ◽  
Down’S Syndrome

Down’s syndrome with congenital acute leukemia and congenital heart disease

2020 ◽  
pp. 111
Author(s):  
O.V. Petrova ◽  
O.I. Murygina ◽  
S.A. Shashin ◽  
D.M. Nikulina ◽  
D.G. Tarasov
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Acute Leukemia ◽  
Congenital Heart ◽  
Down's Syndrome ◽  
Down’S Syndrome
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