scholarly journals Elevation of Soluble Intercellular Adhesion Molecule-1 Levels, but Not Angiopoietin 2, in the Plasma of Human Immunodeficiency Virus–Infected African Women with Clinical Kaposi Sarcoma

2014 ◽  
Vol 91 (4) ◽  
pp. 705-708
Author(s):  
Susan M. Graham ◽  
Julie Overbaugh ◽  
Barbra A. Richardson ◽  
Walter Jaoko ◽  
W. Conrad Liles ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Adhesion Molecule ◽  
Kaposi Sarcoma ◽  
Intercellular Adhesion ◽  
African Women ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
Immunodeficiency Virus ◽  
Soluble Intercellular Adhesion Molecule ◽  
Angiopoietin 2

scholarly journals Statin Compounds Reduce Human Immunodeficiency Virus Type 1 Replication by Preventing the Interaction between Virion-Associated Host Intercellular Adhesion Molecule 1 and Its Natural Cell Surface Ligand LFA-1

2004 ◽  
Vol 78 (21) ◽  
pp. 12062-12065 ◽  
Author(s):  
Jean-François Giguère ◽  
Michel J. Tremblay
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
Immunodeficiency Virus ◽  
Hiv 1

ABSTRACT A variety of host factors, including membrane proteins acquired by human immunodeficiency virus type 1 (HIV-1), play a dominant role in HIV-1 adsorption onto host cells. Examples include the integrin intercellular adhesion molecule 1 (ICAM-1), which, once acquired by HIV-1, promotes virus infectivity via ligation to LFA-1. We tested the ability of statins to diminish HIV-1 replication, based on the idea that these compounds have been shown to block ICAM-1-LFA-1 interactions. Our data indicate that statins diminish HIV-1 attachment to target cells by suppressing ICAM-1-LFA-1 interactions. The capacity of statins to limit the initial steps in virus replication could represent an interesting approach for the treatment of HIV-1 infection.

scholarly journals Variability of Serum Soluble Intercellular Adhesion Molecule-1 Measurements Attributable to a Common Polymorphism

2004 ◽  
Vol 50 (11) ◽  
pp. 2185-2187 ◽  
Author(s):  
Thomas C Register ◽  
Kathryn P Burdon ◽  
Leon Lenchik ◽  
Donald W Bowden ◽  
Gregory A Hawkins ◽  
...  
Keyword(s):  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
Common Polymorphism ◽  
Soluble Intercellular Adhesion Molecule

scholarly journals Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma

2018 ◽  
Vol 34 (2) ◽  
pp. 309-317 ◽  
Author(s):  
Vera S. Schellerer ◽  
Melanie C. Langheinrich ◽  
Veronika Zver ◽  
Robert Grützmann ◽  
Michael Stürzl ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Prognostic Marker ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
Soluble Intercellular Adhesion Molecule
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