Variations in The Apparent Diffusion Coefficient Based on The Number of Applied B-Values in Brain Parenchymal Tissue on Diffusion Weighted Magnetic Resonance Imaging

2019 ◽  
Vol 24 (2) ◽  
pp. 286-293
Author(s):  
Sung Jin Kang ◽  
A Leum Lee
2013 ◽  
Vol 6 ◽  
pp. MRI.S11149 ◽  
Author(s):  
Melanie Martin

This article reviews a new concept in magnetic resonance as applied to cellular and biological systems. Diffusion weighted magnetic resonance imaging can be used to infer information about restriction sizes of samples being measured. The measurements rely on the apparent diffusion coefficient changing with diffusion times as measurements move from restricted to free diffusion regimes. Pulsed gradient spin echo (PGSE) measurements are limited in the ability to shorten diffusion times and thus are limited in restriction sizes which can be probed. Oscillating gradient spin echo (OGSE) measurements could provide shorter diffusion times so smaller restriction sizes could be probed.


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