scholarly journals Spectrophotometric study of the charge transfer complexation of some amino acid derivative drugs as electron donors with 7,7,8,8-tetracyanoquinodimethane

Author(s):  
Sheng Yun Li ◽  
Qiao Lin Guo ◽  
Wen Yuan ◽  
Yu Cui Hou ◽  
Li Ming Du
2021 ◽  
Vol 98 (1) ◽  
pp. 100004
Author(s):  
Nao Otani ◽  
Tetsundo Furuya ◽  
Natsuki Katsuumi ◽  
Tomoyuki Haraguchi ◽  
Takashiro Akitsu

2011 ◽  
Vol 378 (1-2) ◽  
pp. 531-540 ◽  
Author(s):  
Kripal Singh ◽  
Pravin G. Ingole ◽  
Jayesh Chaudhari ◽  
Harshad Bhrambhatt ◽  
Amit Bhattacharya ◽  
...  

2016 ◽  
Vol 22 (46) ◽  
pp. 16429-16432 ◽  
Author(s):  
Yuki Kaji ◽  
Naohiro Uemura ◽  
Yoshio Kasashima ◽  
Hiroki Ishikawa ◽  
Yasushi Yoshida ◽  
...  

ACS Omega ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Fumihiko Iwasaki ◽  
Keishi Suga ◽  
Yukihiro Okamoto ◽  
Hiroshi Umakoshi

2010 ◽  
Vol 46 (12) ◽  
pp. 2094 ◽  
Author(s):  
Mark A. Sephton ◽  
Christopher R. Emerson ◽  
Lev N. Zakharov ◽  
Paul R. Blakemore

2002 ◽  
Vol 85 (5) ◽  
pp. 1003-1008 ◽  
Author(s):  
Sheikha Al-Ghannam ◽  
Fathalla Belal

Abstract A simple charge-transfer complexation method is described for the spectrophotometric assay of nizatidine, ranitidine, and famotidine. This method is based on interaction of these drugs, as n-electron donors, with 7,7,8,8-tetracyanoquinodimethane, as the π-acceptor, in acetonitrile to give highly colored green radical anions that are measured at 840 nm. Calibration graphs for the 3 compounds are linear over the concentration ranges of 1–6 μg/mL for nizatidine and ranitidine and 1–7 μg/mL for famotidine, with correlation coefficients (n = 6) of >0.999. The conditioned stability constants and the free energy changes were measured; the values obtained were generally high and negative, respectively, suggesting highly stable complexes. The proposed method was successfully applied to the determination of the drugs in pharmaceutical preparations. The assay results were in accordance with those obtained by using reference methods.


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