scholarly journals Safety of blood transfusion: prevalence of hepatitis B surface antigen in blood donors in Zaria, Northern Nigeria

2006 ◽  
Vol 7 (3) ◽  
Author(s):  
HM Muktar ◽  
AM Suleiman ◽  
M Jones
2018 ◽  
Vol 4 (1) ◽  
pp. 68-74
Author(s):  
Olusogo Ebenezer Busari ◽  
Omotola Toyin Ojo ◽  
Yetunde Adebisi Aken'Ova

Background: There have been cases of post-transfusion hepatitis in spite of transfusion of hepatitis B surface antigen negative blood unit. Objective: To determine the socio-demographic and risk factors associated with positivity of anti-HBc among Hepatitis B surface antigen negative blood donors. Methods: A cross-sectional study was carried out among 490 HBsAg negative blood donors. The participants were tested for anti-HBc using ELISA kits. A structured questionnaire was used to obtain socio-demographic data and other possible risk factors. Results: The mean age of the participants was 32.5 ± 9.5 years with male predominance of 462 (94.3%) while 375 (76.5%) were first time donors. Of the 490 HBsAg negative blood donors, 89 (18.2%) were positive for anti-HBc. The highest prevalence of anti-HBc occurred in the 26-34 years age group. Independent risk factors associated with the presence of anti-HBc included age (p = 0.049), marital status (p = 0.003), dental and surgical procedure (p<0.001), traditional practices such as tattoo, body piercing and scarification (p<0.001) and previous blood transfusion (p = 0.016). Conclusion: Age, marital status, traditional and cultural practices like scarifications, tattoo and body piercing and history of blood transfusion were risk factors associated with HBV infection despite HBsAg negativity.


1989 ◽  
Vol 3 (3) ◽  
pp. 237-241 ◽  
Author(s):  
Timothy Iga ◽  
D. V. Babona ◽  
G. T. Nurse

A paper published in the Medical Journal of Australia in 1972 gave a breakdown of Port Moresby blood donors by HBS Ag carrier status and area of origin. It has lately become possible to test whether such geographical subsamples provide reliable evidence of the carrier status in the home areas, and it appears that, except for the Islands provinces, they do not. Traditional lifestyles conduce to the maintenance and spread of the virus, which is much more prevalent in the provinces than in the capital.


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