scholarly journals Severe meningoencephalitis secondary to calvarial invasion of Lagenidium giganteum forma caninum in a dog

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Justin Shmalberg ◽  
Patrick S. Moyle ◽  
William F. Craft ◽  
Stuart A. Walton
Keyword(s):  
Surgical Resection ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Fungal Culture ◽  
Neurologic Disease ◽  
Caninum Infection ◽  
Pythium Insidiosum ◽  
Lagenidium Giganteum ◽  
The Right

Background: The oomycete Lagenidium giganteum forma caninum is an uncommon cause of severe dermal and subcutaneous infections in dogs with possible vascular invasion and other fatal sequelae. Infection within the central nervous system of affected dogs has not been previously reported.Case Description: A 6-year-old spayed female mixed-breed dog was evaluated at a referral institution with a 2-month history of suspected fungal infection in the region of the right mandibular lymph node that was refractory to surgical resection and empiric medical therapy. Physical examination identified a 6-cm fluctuant subcutaneous mass caudoventral to the ramus of the right mandible and a second firm mass in the region of the right caudal maxilla. Lesional punch biopsies were submitted for fungal culture and polymerase chain reaction (PCR), which subsequentlyidentified L. giganteum forma caninum infection. Initial treatment consisted of anti-inflammatory doses of prednisone and hyperbaric oxygen therapy. Four weeks following initial evaluation, the patient was presented with progressive neurological signs consistent with a forebrain lesion. Magnetic resonance imaging revealed soft-tissue, contrastenhancing lesions ventral to the calvarium adjacent to the site of original surgical resection and throughout the brain. Humane euthanasia was elected, and postmortem examination was consistent with the extension of local disease from the right masseter muscle into the right ventral calvarium. Postmortem DNA sequencing confirmed the identity of the organism as L. giganteum forma caninum.Conclusion: This is the first reported case of intracranial lagenidiosis in the dog. PCR distinguished this species from other Lagenidium species and from oomycetes of other genera, such as Pythium insidiosum and Paralagenidium karlingii. Regional extension of cutaneous lagenidiosis should therefore be considered in cases with concurrent or spontaneous neurologic disease. Keywords: Hyperbaric oxygen therapy, Lagenidium giganteum forma caninum, Neurologic disease, Oomycete.

Late-stage sequela of an isolated optic neuropathy after acute magnesium valproate overdose: A case report

2020 ◽  
pp. 112067212097494
Author(s):  
Xuhao Chen ◽  
Haohao Di ◽  
Ying Hong ◽  
Chun Zhang
Keyword(s):  
Visual Acuity ◽  
Optic Nerve ◽  
Hyperbaric Oxygen ◽  
Optic Neuropathy ◽  
Visual Function ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Early Stage ◽  
Systemic Treatments ◽  
The Right

Background: Magnesium valproate is a valproic acid (VPA) derivative that is widely used for the treatment of epilepsy and bipolar disorders. Acute overdose of VPA may cause complicated systemic syndromes; however, the reports of ocular sequelae caused by toxic optic neuropathy (TON) are rare. Case presentation: We present a case of a 19-year-old female with bilateral damage to visual function after acute VPA overdose. She was comatose and received systemic treatments for 1 month, during which she suffered a substantial loss of visual function without any evident neurological sequelae. The first recorded visual acuity was no light perception in the right eye (OD) and hand motion in the left eye (OS). Her best-corrected visual acuity improved to 20/100 OS after 4 months of hyperbaric oxygen therapy and neurotrophic treatments. Her visual field was limited to an inferior nasal area OS. Therefore, a diagnosis of TON was made. Her visual function remained stable in the left eye, but did not recover in the right eye during the 5-month follow-up. We found damage to the optic nerve pathway during ophthalmic examinations. Conclusion: We report a rare case of TON caused by acute VPA overdose. Hyperbaric oxygen therapy, and neuroprotective and neurotrophic treatments might be effective at the early stage but cannot fully reverse the damage to the optic nerve. The present case indicates the potential neurotoxicity of VPA. It is crucial to determine the severity of an isolated optic nerve sequela caused by VPA overdose, though it might be rare as observed in previous reports. Further confirmation of the likelihood of its causation and its pathophysiology is needed in the future.

scholarly journals A Successful Treatment of Chronic Migraine With Hyperbaric Oxygen Therapy

EMJ Neurology ◽  
2021 ◽  
Author(s):  
Rahmah Shafee ◽  
Mohd Amirullah Hamzah ◽  
Rajesh Kumar Muniandy
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Medical Problem ◽  
World Health ◽  
Patient Reported ◽  
Health Organization ◽  
The Right ◽  
To Receive ◽  
Therapy Sessions

The World Health Organization (WHO) ranks migraine as the most prevalent and disabling neurological condition. Management of migraines can be broadly divided into lifestyle and trigger management, acute treatments, and preventive treatments. Despite pharmacological advances, this medical problem has remained undertreated. A 40-year-old male presented to the authors’ hospital and complained of severe, constant, and throbbing pain over the right side of his head. There was occasional photophobia but no visual disturbances. Oral analgesics were not helpful. After careful evaluation, he was advised to receive hyperbaric oxygen therapy sessions. He underwent one session per day, 5 days per week for 4 weeks. At the end of the 20 sessions, the patient reported an improvement in his symptoms, and did not require any oral medication. The authors concluded that hyperbaric oxygen therapy should be explored further as a treatment for pharmacologically resistant migraine.

scholarly journals Hyperbaric oxygen therapy caused tympanic membrane and ventricular hemorrhage: a case report

2021 ◽  
Vol 11 (3) ◽  
pp. 60-62
Author(s):  
Chunhui Yang
Keyword(s):  
Tympanic Membrane ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Pure Tone Audiometry ◽  
Final Diagnosis ◽  
Normal Blood ◽  
Poor Ventilation ◽  
The Right ◽  
Endoscopic Assessment

A 40-year-old male undergoing rehabilitation with hyperbaric oxygen therapy (HBOT) three months after an acute right frontal lobe cerebral infarction. On the second day of HBOT, he felt a significant blockage and pain in his left ear during and after the treatment. The endoscopic assessment of the ear and nose revealed haemorrhage in the left ear tympanic membrane and hemorrhagic effusion in the tympanic chamber. The nasal septum was found to be left deviated resulting in significant narrowing of the left nasal cavity and significant poor ventilation. Laboratory tests showed normal blood count and normal blood coagulation count. The final diagnosis of haemorrhage and fluid accumulation in the tympanic chamber of the left ear was made. After the treatment of the middle ear ball blowing once a day for 10 days, the pure tone audiometry of the left ear reached the level of the right ear, and the blockage and pain in the left ear disappeared completely. The orthoscopy inspection indicated total absorption of hemorrhagic fluid in the tympanic chamber of the left ear. This is the first report that HBOT caused tympanic membrane haemorrhage and offers new insights into the prevention of comorbidities in HBOT.

scholarly journals The Use of Hyperbaric Oxygen Therapy for Ear Reconstruction: A Case Series

2021 ◽  
Vol 8 (2) ◽  
pp. 93-98
Author(s):  
Marcella Tirza Tulong ◽  
Mendy Hatibie Oley ◽  
Maximillian Christian Oley ◽  
Ali Sundoro ◽  
Muhammad Faruk
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Traumatic Injury ◽  
Case Series ◽  
Ear Reconstruction ◽  
Hyperbaric Treatment ◽  
First Case ◽  
The Right

Introduction: The unique anatomy of the ear makes the reconstruction more challenging. Microtia and auricula hematomas are deformities or defects that can occur in the ear. Treating traumatic injury and congenital malformations of the ears needs some technique and expertise. Hyperbaric Oxygen Therapy is an additional therapy that makes a significant contribution and is effective in wound healing. Case Series: In our first case, a 52-year-old man presented with a traumatic right cauliflower ear due to a traffic accident two weeks before hospital admission. The second case involves a boy 14-year-old who has a Microtia in the right ear with total ear construction performed using autologous costochondral cartilage techniques in a two-stage. Results: Both cases following hyperbaric oxygen therapy, yield good results with good scars, no sign of infection nor tissue necrosis Summary: The combination therapy of reconstructive surgery and administration of oxygen therapy gave satisfactory results in both cases. Five sessions of hyperbaric treatment showed promising results. There is no infection, rapid wound healing, and cessation of flap compromise.

Idiopathic Sternoclavicular Osteomyelitis Masquerading as a Pyomyositis Medically Managed with Antibiotics and Hyperbaric Oxygen

2010 ◽  
Vol 2 (2) ◽  
pp. 107-110
Author(s):  
Richard Felwick ◽  
Mark Farrar ◽  
Sally Parry
Keyword(s):  
Magnetic Resonance Imaging ◽  
Staphylococcus Aureus ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Spinal Manipulation ◽  
Oxygen Therapy ◽  
Sternoclavicular Joint ◽  
Resonance Imaging ◽  
Intravenous Antibiotics ◽  
The Right

We report the case of a patient who presented with erythema and swelling over the chest and neck following chiropractic spinal manipulation. Staphylococcus aureus pyomyositis of the right sternocleidomastoid was initially diagnosed, although subsequent magnetic resonance imaging confirmed sepsis arising from the sternoclavicular joint. This was treated successfully with a prolonged course of intravenous antibiotics and hyperbaric oxygen therapy. Sternoclavicular osteomyelitis is usually managed with surgical resection and rarely medically. To our knowledge, this is the first report of a sternoclavicular osteomyelitis successfully managed with a combination of antibiotics and hyperbaric oxygen therapy.

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