scholarly journals A Successful Treatment of Chronic Migraine With Hyperbaric Oxygen Therapy

EMJ Neurology ◽  
2021 ◽  
Author(s):  
Rahmah Shafee ◽  
Mohd Amirullah Hamzah ◽  
Rajesh Kumar Muniandy
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Medical Problem ◽  
World Health ◽  
Patient Reported ◽  
Health Organization ◽  
The Right ◽  
To Receive ◽  
Therapy Sessions

The World Health Organization (WHO) ranks migraine as the most prevalent and disabling neurological condition. Management of migraines can be broadly divided into lifestyle and trigger management, acute treatments, and preventive treatments. Despite pharmacological advances, this medical problem has remained undertreated. A 40-year-old male presented to the authors’ hospital and complained of severe, constant, and throbbing pain over the right side of his head. There was occasional photophobia but no visual disturbances. Oral analgesics were not helpful. After careful evaluation, he was advised to receive hyperbaric oxygen therapy sessions. He underwent one session per day, 5 days per week for 4 weeks. At the end of the 20 sessions, the patient reported an improvement in his symptoms, and did not require any oral medication. The authors concluded that hyperbaric oxygen therapy should be explored further as a treatment for pharmacologically resistant migraine.

Late-stage sequela of an isolated optic neuropathy after acute magnesium valproate overdose: A case report

2020 ◽  
pp. 112067212097494
Author(s):  
Xuhao Chen ◽  
Haohao Di ◽  
Ying Hong ◽  
Chun Zhang
Keyword(s):  
Visual Acuity ◽  
Optic Nerve ◽  
Hyperbaric Oxygen ◽  
Optic Neuropathy ◽  
Visual Function ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Early Stage ◽  
Systemic Treatments ◽  
The Right

Background: Magnesium valproate is a valproic acid (VPA) derivative that is widely used for the treatment of epilepsy and bipolar disorders. Acute overdose of VPA may cause complicated systemic syndromes; however, the reports of ocular sequelae caused by toxic optic neuropathy (TON) are rare. Case presentation: We present a case of a 19-year-old female with bilateral damage to visual function after acute VPA overdose. She was comatose and received systemic treatments for 1 month, during which she suffered a substantial loss of visual function without any evident neurological sequelae. The first recorded visual acuity was no light perception in the right eye (OD) and hand motion in the left eye (OS). Her best-corrected visual acuity improved to 20/100 OS after 4 months of hyperbaric oxygen therapy and neurotrophic treatments. Her visual field was limited to an inferior nasal area OS. Therefore, a diagnosis of TON was made. Her visual function remained stable in the left eye, but did not recover in the right eye during the 5-month follow-up. We found damage to the optic nerve pathway during ophthalmic examinations. Conclusion: We report a rare case of TON caused by acute VPA overdose. Hyperbaric oxygen therapy, and neuroprotective and neurotrophic treatments might be effective at the early stage but cannot fully reverse the damage to the optic nerve. The present case indicates the potential neurotoxicity of VPA. It is crucial to determine the severity of an isolated optic nerve sequela caused by VPA overdose, though it might be rare as observed in previous reports. Further confirmation of the likelihood of its causation and its pathophysiology is needed in the future.

scholarly journals Hyperbaric oxygen therapy as an adjunctive treatment for descending necrotizing mediastinitis: about 6 cases

2020 ◽  
Vol 7 (11) ◽  
pp. 3647
Author(s):  
Zribi Hazem ◽  
Ammar Abdulrehamen ◽  
Abdelkabir Amina ◽  
Ben Ayed Ahmed ◽  
Touil Ameny ◽  
...  
Keyword(s):  
Adjuvant Therapy ◽  
Antibiotic Treatment ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Descriptive Study ◽  
Clinical Results ◽  
Adjunctive Treatment ◽  
Therapy Sessions ◽  
Objective Study

Background: The objective study was to evaluate the use and the effectiveness of hyperbaric oxygen therapy as an adjuvant therapy in 6 cases of descending necrotizing mediastinitis.Methods: This is a retrospective descriptive study, performed between 2010 and 2019. Hyperbaric oxygen therapy was indicated in difficult clinical management cases despite surgery and antibiotic therapy.Results: Six patients had oxygen therapy sessions in addition to antibiotic treatment and surgery. There was marked clinical and radiological improvement in 5 cases. Only one patient died in a septic shock.Conclusions: Hyperbaric oxygen therapy, as adjuvant therapy to surgery and antibiotic treatment, can increase survival and provide good clinical results.

A retrospective case series looking at the effectiveness of hyperbaric oxygen in treating radiation cystitis.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 127-127 ◽  
Author(s):  
Scott Gorenstein ◽  
Aaron Katz ◽  
Kimberly Regan ◽  
Donna Hangan
Keyword(s):  
Radiation Therapy ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Radiation Treatment ◽  
Case Series ◽  
University Hospital ◽  
Radiation Cystitis ◽  
Patient Reported ◽  
Radiation Induced

127 Background: A side effect of radiation therapy to treat genitourinary cancers is radiation-induced cystitis, which in its most severe form can be hemorrhagic cystitis (HC). Some studies have found the incidence of HC in radiation patients to range from 3% to 6.5% after radiation therapy and can develop anywhere from 6 months after radiation therapy to 10 years or more after the last treatment. The severity of symptoms, which includes hematuria, may drastically reduce quality of life. Recent studies have shown that hyperbaric oxygen therapy has improved symptoms of radiation cystitis in around 80% of patients. Methods: Sixty patients who received hyperbaric oxygen therapy (HBOT) for radiation-induced cystitis since 2010 at Winthrop University Hospital were identified. IRB approval was obtained for contacting these patients to gather outcome data. Patient reported outcomes were evaluated using a questionnaire that assessed the type and duration of radiation treatment, treatment other than HBOT for HC symptoms, surgical intervention, and patient perceived outcomes of HBOT. Results: 36 patients were consented. The average age of the patient was 71 with a range from 29-91. The majority of the patients 78% had prostate cancer with the Colon, Uterinem, Bladder and Testicular cancer also included The average time from completion of radiation to onset of symptoms was 3 years. The mean number of treatments was 35 with a range of 18-120 treatments. All treatments were for 90 minutes at 2.4 ATA. The majority of the patients (24) had external beam radiaiation and 12 patients had a urological procedure after completion of their therapy. 78 % of the patients reports either moderate improvement or complete resolution of symptoms. Conclusions: This case series seems to demonstrate that Hyperbaric Oxygen Therapy appears to be an effective treatment for radiation cystitis, however additional studies are necessary.

scholarly journals Hyperbaric oxygen therapy caused tympanic membrane and ventricular hemorrhage: a case report

2021 ◽  
Vol 11 (3) ◽  
pp. 60-62
Author(s):  
Chunhui Yang
Keyword(s):  
Tympanic Membrane ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Pure Tone Audiometry ◽  
Final Diagnosis ◽  
Normal Blood ◽  
Poor Ventilation ◽  
The Right ◽  
Endoscopic Assessment

A 40-year-old male undergoing rehabilitation with hyperbaric oxygen therapy (HBOT) three months after an acute right frontal lobe cerebral infarction. On the second day of HBOT, he felt a significant blockage and pain in his left ear during and after the treatment. The endoscopic assessment of the ear and nose revealed haemorrhage in the left ear tympanic membrane and hemorrhagic effusion in the tympanic chamber. The nasal septum was found to be left deviated resulting in significant narrowing of the left nasal cavity and significant poor ventilation. Laboratory tests showed normal blood count and normal blood coagulation count. The final diagnosis of haemorrhage and fluid accumulation in the tympanic chamber of the left ear was made. After the treatment of the middle ear ball blowing once a day for 10 days, the pure tone audiometry of the left ear reached the level of the right ear, and the blockage and pain in the left ear disappeared completely. The orthoscopy inspection indicated total absorption of hemorrhagic fluid in the tympanic chamber of the left ear. This is the first report that HBOT caused tympanic membrane haemorrhage and offers new insights into the prevention of comorbidities in HBOT.

scholarly journals The Use of Hyperbaric Oxygen Therapy for Ear Reconstruction: A Case Series

2021 ◽  
Vol 8 (2) ◽  
pp. 93-98
Author(s):  
Marcella Tirza Tulong ◽  
Mendy Hatibie Oley ◽  
Maximillian Christian Oley ◽  
Ali Sundoro ◽  
Muhammad Faruk
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Traumatic Injury ◽  
Case Series ◽  
Ear Reconstruction ◽  
Hyperbaric Treatment ◽  
First Case ◽  
The Right

Introduction: The unique anatomy of the ear makes the reconstruction more challenging. Microtia and auricula hematomas are deformities or defects that can occur in the ear. Treating traumatic injury and congenital malformations of the ears needs some technique and expertise. Hyperbaric Oxygen Therapy is an additional therapy that makes a significant contribution and is effective in wound healing. Case Series: In our first case, a 52-year-old man presented with a traumatic right cauliflower ear due to a traffic accident two weeks before hospital admission. The second case involves a boy 14-year-old who has a Microtia in the right ear with total ear construction performed using autologous costochondral cartilage techniques in a two-stage. Results: Both cases following hyperbaric oxygen therapy, yield good results with good scars, no sign of infection nor tissue necrosis Summary: The combination therapy of reconstructive surgery and administration of oxygen therapy gave satisfactory results in both cases. Five sessions of hyperbaric treatment showed promising results. There is no infection, rapid wound healing, and cessation of flap compromise.

Hyperbaric oxygen therapy in preventing mechanical ventilation in COVID-19 patients: a retrospective case series

2020 ◽  
Vol 29 (Sup5a) ◽  
pp. S4-S8 ◽  
Author(s):  
Kerry Thibodeaux ◽  
Marcus Speyrer ◽  
Amer Raza ◽  
Raphael Yaakov ◽  
Thomas E Serena
Keyword(s):  
Mechanical Ventilation ◽  
Oxygen Saturation ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Small Sample ◽  
World Health ◽  
Cardiac Complications ◽  
Dramatic Improvement ◽  
Increased Risk

Objective: A pandemic afflicts the entire world. The highly contagious SARS-CoV-2 virus originated in Wuhan, China in late 2019 and rapidly spread across the entire globe. According to the World Health Organization (WHO), the novel Coronavirus (COVID-19)has infected more than two million people worldwide, causing over 160,000 deaths. Patients with COVID-19 disease present with a wide array of symptoms, ranging from mild flu-like complaints to life threatening pulmonary and cardiac complications. Older people and patients with underlying disease have an increased risk of developing severe acute respiratory syndrome (SARS) requiring mechanical ventilation. Once intubated, mortality increases exponentially. A number of pharmacologic regimens, including hydroxychloroquine-azithromycin, antiviral therapy (eg, remdesevir), and anti-IL-6 agents (e.g., toclizumab), have been highlighted by investigators over the course of the pandemic, based on the therapy's potential to interrupt the viral life-cycle of SARS-CoV-2 or preventing cytokine storm. At present, there have been no conclusive series of reproducible randomised clinical trials demonstrating the efficacy of any one drug or therapy for COVID-19. Cases: COVID-19 positive patients (n=5) at a single institution received hyperbaric oxygen therapy (HBOT) between 13 and 20 April 2020. All the patients had tachypnoea and low oxygen saturation despite receiving high FiO2. HBOT was added to prevent the need for mechanical ventilation. A standard dive profile of 2.0ATA for 90 minutes was employed. Patients received between one and six treatments in one of two dedicated monoplace hyperbaric chambers. Results: All the patients recovered without the need for mechanical ventilation. Following HBOT, oxygen saturation increased, tachypnoea resolved and inflammatory markers fell. At the time of writing, three of the five patients have been discharged from the hospital and two remain in stable condition. Conclusion: This small sample of patients exhibited dramatic improvement with HBOT. Most importantly, HBOT potentially prevented the need for mechanical ventilation. Larger studies are likely to define the role of HBOT in the treatment of this novel disease.

scholarly journals Severe meningoencephalitis secondary to calvarial invasion of Lagenidium giganteum forma caninum in a dog

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Justin Shmalberg ◽  
Patrick S. Moyle ◽  
William F. Craft ◽  
Stuart A. Walton
Keyword(s):  
Surgical Resection ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Fungal Culture ◽  
Neurologic Disease ◽  
Caninum Infection ◽  
Pythium Insidiosum ◽  
Lagenidium Giganteum ◽  
The Right

Background: The oomycete Lagenidium giganteum forma caninum is an uncommon cause of severe dermal and subcutaneous infections in dogs with possible vascular invasion and other fatal sequelae. Infection within the central nervous system of affected dogs has not been previously reported.Case Description: A 6-year-old spayed female mixed-breed dog was evaluated at a referral institution with a 2-month history of suspected fungal infection in the region of the right mandibular lymph node that was refractory to surgical resection and empiric medical therapy. Physical examination identified a 6-cm fluctuant subcutaneous mass caudoventral to the ramus of the right mandible and a second firm mass in the region of the right caudal maxilla. Lesional punch biopsies were submitted for fungal culture and polymerase chain reaction (PCR), which subsequentlyidentified L. giganteum forma caninum infection. Initial treatment consisted of anti-inflammatory doses of prednisone and hyperbaric oxygen therapy. Four weeks following initial evaluation, the patient was presented with progressive neurological signs consistent with a forebrain lesion. Magnetic resonance imaging revealed soft-tissue, contrastenhancing lesions ventral to the calvarium adjacent to the site of original surgical resection and throughout the brain. Humane euthanasia was elected, and postmortem examination was consistent with the extension of local disease from the right masseter muscle into the right ventral calvarium. Postmortem DNA sequencing confirmed the identity of the organism as L. giganteum forma caninum.Conclusion: This is the first reported case of intracranial lagenidiosis in the dog. PCR distinguished this species from other Lagenidium species and from oomycetes of other genera, such as Pythium insidiosum and Paralagenidium karlingii. Regional extension of cutaneous lagenidiosis should therefore be considered in cases with concurrent or spontaneous neurologic disease. Keywords: Hyperbaric oxygen therapy, Lagenidium giganteum forma caninum, Neurologic disease, Oomycete.

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