Challenging the Problem of ‘Fit': Advancing the Regenerative Medicine Industries in the United States, Britain and Japan

2021 ◽  
pp. 72-96
Author(s):  
Maki Umemura
Keyword(s):  
United States ◽  
Regenerative Medicine ◽  
The United States

Considerations for Tissue-Engineered and Regenerative Medicine Product Development Prior to Clinical Trials in the United States

2010 ◽  
Vol 16 (1) ◽  
pp. 41-54 ◽  
Author(s):  
Mark H. Lee ◽  
Judith A. Arcidiacono ◽  
Anastacia M. Bilek ◽  
Jeremiah J. Wille ◽  
Caitilin A. Hamill ◽  
...  
Keyword(s):  
United States ◽  
Clinical Trials ◽  
Regenerative Medicine ◽  
Product Development ◽  
The United States ◽  
Medicine Product

Comparison of the effect of cigarette smoke on mesenchymal stem cells and dental stem cells

2020 ◽  
Author(s):  
Brandon Nguyen ◽  
Tamer Alpagot ◽  
Heesoo Oh ◽  
David Ojcius ◽  
Nan Xiao
Keyword(s):  
United States ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Regenerative Medicine ◽  
Cigarette Smoking ◽  
Cigarette Smoke ◽  
The United States ◽  
Systemic Effects ◽  
Dental Stem Cells ◽  
The Impact

The persistent prevalence of cigarette smoking continues to contribute to preventable disease and death in the United States. Although much is known about the deleterious systemic effects of cigarette smoke and nicotine, some clinically relevant areas still remain unclear, such as the impact of cigarette smoke and nicotine on stem cells and the subsequent implications in regenerative medicine. This review focuses on recent studies on the effect of cigarette smoke and one of its deleterious components nicotine on mesenchymal stem cells, with an emphasis on dental stem cells.

Translation of Regenerative Medicine Products Into the Clinic in the United States

2015 ◽  
pp. 49-74 ◽  
Author(s):  
Mark H. Lee ◽  
Patrick Au ◽  
John Hyde ◽  
Carmen Gacchina Johnson ◽  
Mohammad Heidaran ◽  
...  
Keyword(s):  
United States ◽  
Regenerative Medicine ◽  
The United States

scholarly journals Prospects for Harmonizing Regulatory Science Programs in Europe, Japan, and the United States to Advance Regenerative Medicine

2016 ◽  
Vol 50 (6) ◽  
pp. 724-733 ◽  
Author(s):  
Christopher-Paul Milne ◽  
James Mittra ◽  
Naoko Kojima ◽  
Daisuke Sugiyama ◽  
Josephine Awatin ◽  
...  
Keyword(s):  
United States ◽  
Regenerative Medicine ◽  
The United States ◽  
Regulatory Science

Correlative microscopy in distrubuted (client/server) computing environments: tools for catalyzing the rapid dissemination of information about the cell biology of the human prostate

1995 ◽  
Vol 53 ◽  
pp. 682-683
Author(s):  
A. Hakam ◽  
J.T. Gau ◽  
M.L. Grove ◽  
B.A. Evans ◽  
M. Shuman ◽  
...  
Keyword(s):  
United States ◽  
Cell Biology ◽  
Tissue Bank ◽  
The United States ◽  
Prostate Adenocarcinoma ◽  
Correlative Microscopy ◽  
Client Server ◽  
Critical Elements ◽  
Transplant Organ

Prostate adenocarcinoma is the most common malignant tumor of men in the United States and is the third leading cause of death in men. Despite attempts at early detection, there will be 244,000 new cases and 44,000 deaths from the disease in the United States in 1995. Therapeutic progress against this disease is hindered by an incomplete understanding of prostate epithelial cell biology, the availability of human tissues for in vitro experimentation, slow dissemination of information between prostate cancer research teams and the increasing pressure to “ stretch” research dollars at the same time staff reductions are occurring.To meet these challenges, we have used the correlative microscopy (CM) and client/server (C/S) computing to increase productivity while decreasing costs. Critical elements of our program are as follows:1) Establishing the Western Pennsylvania Genitourinary (GU) Tissue Bank which includes >100 prostates from patients with prostate adenocarcinoma as well as >20 normal prostates from transplant organ donors.

Digital image acquisition, processing, and analysis in a polymer microscopy laboratory

1994 ◽  
Vol 52 ◽  
pp. 454-455
Author(s):  
Vinod K. Berry ◽  
Xiao Zhang
Keyword(s):  
United States ◽  
Image Analysis ◽  
Digital Image ◽  
Image Acquisition ◽  
Image Transmission ◽  
The United States ◽  
Quantitative Image Analysis ◽  
Quantitative Image

In recent years it became apparent that we needed to improve productivity and efficiency in the Microscopy Laboratories in GE Plastics. It was realized that digital image acquisition, archiving, processing, analysis, and transmission over a network would be the best way to achieve this goal. Also, the capabilities of quantitative image analysis, image transmission etc. available with this approach would help us to increase our efficiency. Although the advantages of digital image acquisition, processing, archiving, etc. have been described and are being practiced in many SEM, laboratories, they have not been generally applied in microscopy laboratories (TEM, Optical, SEM and others) and impact on increased productivity has not been yet exploited as well.In order to attain our objective we have acquired a SEMICAPS imaging workstation for each of the GE Plastic sites in the United States. We have integrated the workstation with the microscopes and their peripherals as shown in Figure 1.

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