Political violence is a key theme in understanding the historical and contemporary Middle East characterized by different religious, social, and political revolts. It is thus salient to analyze why political violence emerges, how it is diffused, and why it takes different configurations during insurgencies. In order to study these questions, this article establishes three analytical frameworks: interdependency among violence and social movements, diffusion of violence, and proxy warfare. First, I argue that political violence and mobilization are interdependent processes which are shaped by personal, local, and historical dynamics. Secondly, violence is more likely to spread among the societies displaying similar political, religious, or ethnic characteristics, in particular, if there are individuals and militant organizations who take it as a model in order to affect the conflict. Finally, this violence, which depends on local and regional factors, often intersects with global politics and its path is altered as a result.