scholarly journals II-34 Complications of valve replacement related to prosthetic heart valves within one month after surgery

1981 ◽  
Vol 11 (3) ◽  
pp. 204-206
Author(s):  
Y. Soma
Keyword(s):  
Valve Replacement ◽  
Heart Valves ◽  
Prosthetic Heart Valves

Technique of surgical aortic valve implantation using single interrupted annular sutures

2020 ◽  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Heart Valves ◽  
Intraoperative Complications ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Prosthetic Heart Valves ◽  
Surgical Aortic Valve Replacement ◽  
Conduction Disturbances

The introduction of the first surgical prosthetic heart valves in the early 1960s made effective treatment of aortic valve disease possible. The goal of surgical aortic valve replacement is to replace the diseased aortic valve with a properly functioning, sufficiently large prosthesis while avoiding intraoperative complications such as conduction disturbances, coronary artery occlusion, or paravalvular leaks. Although most commonly, non-everting pledgeted mattress sutures are used to implant the prosthesis during surgical aortic valve replacement , interrupted single sutures without pledgets can be a useful alternative, especially in patients with a small tissue annulus, because they theoretically maximize the orifice available for flow. This tutorial discusses the surgical technique of surgical aortic valve replacement using interrupted single annular sutures.

scholarly journals Transcatheter Tricuspid Valve-in-Valve Replacement Resulting in 4 Different Prosthetic Heart Valves in a Single Patient

2013 ◽  
Vol 61 (2) ◽  
pp. e3 ◽  
Author(s):  
Benoit Daneault ◽  
Mathew R. Williams ◽  
Martin B. Leon ◽  
Jean-Michel Paradis ◽  
Susheel K. Kodali
Keyword(s):  
Valve Replacement ◽  
Tricuspid Valve ◽  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Single Patient ◽  
Valve In Valve

Six-Year Experience with CarboMedics Prosthetic Heart Valves

1996 ◽  
Vol 4 (3) ◽  
pp. 152-156 ◽  
Author(s):  
Zhu Ping ◽  
Long Guo Cui ◽  
Li Zhong Xue ◽  
Feng Shu Sheng ◽  
Meng Hua ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Heart Valves ◽  
Prosthetic Heart Valve ◽  
Functional Class ◽  
Prosthetic Heart Valves ◽  
Class Iii ◽  
Mechanical Prosthesis ◽  
Actuarial Survival

Between July 1989 and July 1995, 89 CarboMedics prosthetic heart valves were implanted in 70 patients (38 males, 32 females) ranging in age from 13 to 54 years (mean 33 years). Forty-one of these patients underwent mitral valve replacement, 10 had aortic valve replacement, and 19 had double aortic and mitral valve replacement. Early mortality was 4.9%, 0%, and 15.8% respectively in these groups. Mean follow-up time was 3.4 years and was 95.4% complete (3 lost). There were 5 late deaths (7.7%); 1 in the mitral group, 1 in the aortic group, and 3 who had double valve replacements. Three of these late deaths were considered valve-related. The 5-year actuarial survival rates, hospital mortality excluded, were 97% for mitral, 88% for aortic, and 88% for double valve replacement. Preoperatively, 80% of the patients were in New York Heart Association functional class III or IV, whereas postoperatively, 99.5% of the patients were in class I or II. No structural failures were observed. There was 1 case of systemic embolism and 1 case of valve thrombosis, neither of these patients were taking anticoagulants. Hemorrhage was the most frequent complication; 1 of 4 events was fatal. A less intensive warfarin regimen and improvement in hepatic function may reduce hemorrhagic risk while maintaining thromboembolic protection. On the basis of this experience, the CarboMedics prosthetic heart valve appears to be an excellent mechanical prosthesis for cardiac valve replacement, in terms of hemodynamic performance and low thrombogenicity, in patients receiving anticoagulants.

scholarly journals Managing Pregnancy with Post Mitral Valve Replacement Presenting Late

2013 ◽  
Vol 8 (1) ◽  
pp. 50-52
Author(s):  
Basanta Lamichhane ◽  
N Paradhan ◽  
SJ Rawal ◽  
A Singh ◽  
SR Bhandari ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Healthy Baby ◽  
Obstetrics And Gynaecology ◽  
Healthy Female ◽  
Ultimate Outcome ◽  
Uneventful Pregnancy

With the increased awareness and emphasis of institutional delivery, there has been an increase in trend of cases of valvular heart disease with pregnancy being reported to tertiary centers. Though rare, cases like post mitral valve replacement (MVR) with pregnancy are often a challenge in terms of management with an outcome of uneventful pregnancy and healthy baby. The management of women with prosthetic heart valves during pregnancy poses a particular challenge as there are no available controlled clinical trials to provide guidelines for effective antithrombotic therapy. Here we present a case of post MVR with pregnancy with an ultimate outcome of a healthy female and uneventful vaginal delivery. Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 1 / Issue 15 / Jan- June, 2013 / 50-52 DOI: http://dx.doi.org/10.3126/njog.v8i1.8866

Adhesiveness of 51Cr-Labelled Platelets

1979 ◽  
Author(s):  
J. Dale ◽  
E. Myhre
Keyword(s):  
Valve Replacement ◽  
Glass Bead ◽  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Platelet Adhesiveness ◽  
Labelling Procedure ◽  
Bead Method

The procedure of labelling platelets may disturb their reactivity, and methods based on measurements of radioactivity may therefore not reflect the survival of representative platelets. To study this, nine patients with prosthetic heart valves were chosen because platelet adhesiveness is reduced to a varying degree after valve replacement. Autologous platelets were labelled by incubation of PRP from 120 ml of ACD-blood with 250 μci 51CrO4 for one hour, and then reinjected. After 16 hours, platelet retention was estimated according to Hellem’s modified glass bead method, in parallel samples, the retention of radioactivity was measured. Labelled and non-labelled platelets were retained in the glass-bead columns to the same degree, indicating that the Labelling procedure did not permanently disturb platelet adhesiveness.

Doppler Hemodynamics of CarboMedics Prosthetic Valves in Aortic Position at Rest and Exercise

1996 ◽  
Vol 4 (3) ◽  
pp. 146-151
Author(s):  
Ichiro Shimada ◽  
Hitoshi Okabayashi ◽  
Takeshi Nishina ◽  
Kenji Minatoya ◽  
Yoshiharu Soga ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Pressure Gradient ◽  
Valve Replacement ◽  
Performance Index ◽  
Heart Valves ◽  
Peak Pressure ◽  
Prosthetic Heart Valves ◽  
Pressure Gradients ◽  
Theoretical Performance

To evaluate the size adequacy of CarboMedics prosthetic heart valves, Doppler pressure gradients after aortic valve replacement were determined at rest and immediately after exercise in 83 patients, at a mean time of 18.8 days after aortic valve replacement with CarboMedics prosthetic heart valves (31 standard and 52 R-series). There were 54 males and 29 females, average age 55 years; 12 had pure aortic stenosis, 47 had aortic regurgitation, and 24 had combined lesions. Exercise significantly increased (p < 0.01) the peak velocity (from 2.50 to 2.88 m/sec), the peak pressure gradient (from 25.9 to 34.6 mm Hg), and the mean pressure gradient (from 13.9 to 18.4 mm Hg). Significant differences were observed even in patients with seemingly large valve sizes. Significant correlation (p < 0.0001) was observed between pressure gradients at rest and immediately after exercise, as well as between pressure gradients and theoretical performance index. A theoretical performance index larger than 1.0 cm2/m2 was needed to obtain a postexercise Doppler peak pressure gradient of less than 60 mm Hg early after aortic valve replacement using either the Carbomedics standard or R-series prosthetic heart valves.

Tissue valve replacement of prosthetic heart valves for thromboembolism

1978 ◽  
Vol 41 (3) ◽  
pp. 512-515 ◽  
Author(s):  
Bruce A. Reitz ◽  
Edward B. Stinson ◽  
Randall B. Griepp ◽  
Norman E. Shumway
Keyword(s):  
Valve Replacement ◽  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Tissue Valve

scholarly journals Continued use of Warfarin in lower dose has safe maternal and neonatal outcomes in pregnant women with Prosthetic Heart Valves

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Shafaq Nadeem ◽  
Shahbaz Ahmad Khilji ◽  
Faisal Ali ◽  
Anjum Jalal
Keyword(s):  
Birth Weight ◽  
Pregnant Women ◽  
Valve Replacement ◽  
Prosthetic Valve ◽  
Heart Valves ◽  
Prosthetic Heart Valves ◽  
Fetal Outcomes ◽  
Maternal And Neonatal Outcomes ◽  
Continued Use ◽  
Pregnant Mothers

Background and Objective: There has been concerns regarding the safety of Warfarin in pregnant females due to its teratogenic potential. At the same time warfarin provides best anticoagulation in patients with prosthetic valves. Various dosage regimes have been tried to strike a balance between safety of mother and the avoidance of congenital anomalies in the newborn. This study was conducted to observe the effect of Warfarin in pregnant mothers taking different doses of warfarin, and their neonatal outcome, in our outdoor patients. Methods: This is a cross sectional observational study conducted at the Faisalabad Institute of Cardiology. The pregnant mothers taking warfarin for prosthetic valve replacement who presented to our specialized clinic between November 2016 to April 2017 were included in the study. These included a total of 75 females between the age of 20-35 years. To compare the dose related effect of warfarin, two groups of the patients were formed. One group comprised of patients taking warfarin ≤5mg while the other group consisted of those who were taking >5mg of warfarin daily. These patients were followed till their delivery. The information was collected about the maternal and fetal outcomes. The maternal outcomes including mode of delivery/miscarriage, peripartum bleeding and any valve related thromboembolic complications. The fetal outcomes included birth weight, maturity, embryopathy and congenital anomaly in the baby. Results: Patient’s mean age was 29.25±3.75 years. The mitral valve replacement was present in 60% patients (n=45) while 25.3% patients (n=19) had aortic valve replacement and 14.7% patients (n=11) had double valve replacement. In this group 30 patients (40%) had taken <5 mg warfarin and 45 patients (60%) had received >5 mg warfarin medicine. Miscarriages, cesarean sections, low birth weight and prematurity were more common in patients receiving warfarin >5 mg with p-values 0.005, 0.046, 0.01 and 0.033 respectively. No case of fetal embryopathy was found in both groups. Conclusion: No case of embryopathy was found in each group which signifies that warfarin in lower doses is safe anticoagulant in patients with prosthetic valve replacements. doi: https://doi.org/10.12669/pjms.37.4.3924 How to cite this:Nadeem S, Khilji SA, Ali F, Jalal A. Continued use of Warfarin in lower dose has safe maternal and neonatal outcomes in pregnant women with Prosthetic Heart Valves. Pak J Med Sci. 2021;37(4):---------. doi: https://doi.org/10.12669/pjms.37.4.3924 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Effect of Dipyridamole and RA 233 on Human Platelet Function in Vitro

1973 ◽  
Vol 29 (03) ◽  
pp. 694-700 ◽  
Author(s):  
Paul L. Rifkin ◽  
Marjorie B. Zucker
Keyword(s):  
Mechanism Of Action ◽  
Human Blood ◽  
Glass Bead ◽  
Heart Valves ◽  
Human Platelet ◽  
Drug Effects ◽  
Simple Relation ◽  
Prosthetic Heart Valves ◽  
Induced Aggregation

SummaryDipyridamole (Persantin) is reported to prolong platelet survival and inhibit embolism in patients with prosthetic heart valves, but its mechanism of action is unknown. Fifty jxM dipyridamole failed to reduce the high percentage of platelets retained when heparinized human blood was passed through a glass bead column, but prolonged the inhibition of retention caused by disturbing blood in vitro. Possibly the prostheses act like disturbance. Although RA 233 was as effective as dipyridamole in inhibiting the return of retention, it was less effective in preventing the uptake of adenosine into erythrocytes, and more active in inhibiting ADP-induced aggregation and release. Thus there is no simple relation between these drug effects.

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