scholarly journals Do antiepileptic drugs cause premature atherosclerosis by disturbing lipid metabolism?

2022 ◽  
Vol 13 (01) ◽  
Keyword(s):  
Lipid Metabolism ◽  
Antiepileptic Drugs ◽  
Premature Atherosclerosis

A Cytochemical Study of Glucose-6-Phosphatase (G-6-PASE) in Cells Participating in Atherogenesis of Rabbit Aorta

1975 ◽  
Vol 33 ◽  
pp. 460-461
Author(s):  
Sidney D. Kobernick ◽  
Edna A. Elfont ◽  
Neddra L. Brooks
Keyword(s):  
Lipid Metabolism ◽  
New Zealand ◽  
Aortic Wall ◽  
Rabbit Aorta ◽  
Plaque Formation ◽  
Metabolic Changes ◽  
Atherosclerotic Plaques ◽  
Cytochemical Study ◽  
Cellular Alteration ◽  
New Zealand White Rabbits

This cytochemical study was designed to investigate early metabolic changes in the aortic wall that might lead to or accompany development of atherosclerotic plaques in rabbits. The hypothesis that the primary cellular alteration leading to plaque formation might be due to changes in either carbohydrate or lipid metabolism led to histochemical studies that showed elevation of G-6-Pase in atherosclerotic plaques of rabbit aorta. This observation initiated the present investigation to determine how early in plaque formation and in which cells this change could be observed.Male New Zealand white rabbits of approximately 2000 kg consumed normal diets or diets containing 0.25 or 1.0 gm of cholesterol per day for 10, 50 and 90 days. Aortas were injected jin situ with glutaraldehyde fixative and dissected out. The plaques were identified, isolated, minced and fixed for not more than 10 minutes. Incubation and postfixation proceeded as described by Leskes and co-workers.

Altered hepatic lipid metabolism in leptin-deficlent mice

2001 ◽  
Vol 120 (5) ◽  
pp. A546-A546
Author(s):  
D SWARTZBASILE ◽  
M GOLDBLATT ◽  
C SVATEK ◽  
M WALTERS ◽  
S CHOI ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Hepatic Lipid Metabolism ◽  
Hepatic Lipid

The Epilepsy Prescriber's Guide to Antiepileptic Drugs

2013 ◽  
Author(s):  
Philip N. Patsalos ◽  
Blaise F.D. Bourgeois
Keyword(s):  
Antiepileptic Drugs

Psychomotor development and minor anomolies in children exposed to antiepileptic drugs in utero: a population-based study

2000 ◽  
Vol 42 (5) ◽  
pp. 356-356
Author(s):  
Katarina Wide ◽  
Birger Winbladh ◽  
Torbjörn Tomson ◽  
Kerstin Sars-Zimmer ◽  
Eva Berggren
Keyword(s):  
Antiepileptic Drugs ◽  
Population Based ◽  
In Utero ◽  
Psychomotor Development ◽  
Population Based Study

Homocysteine concentrations and methionine loading in patients on antiepileptic drugs

2000 ◽  
Vol 101 (4) ◽  
pp. 217-223 ◽  
Author(s):  
T. Apeland ◽  
M. A. Mansoor ◽  
R. E. Standjord ◽  
O. Kristensen
Keyword(s):  
Antiepileptic Drugs

The influence of the mental trauma on the behavior and lipid metabolism in female rats

2007 ◽  
Author(s):  
S. G. Tsikunov ◽  
A. G. Pshenichnaya ◽  
A. G. Kusov ◽  
N. N. Klyueva
Keyword(s):  
Lipid Metabolism ◽  
Female Rats ◽  
Mental Trauma

Phenytoin, Other Antiepileptic Drugs Accelerate Bone Loss

2005 ◽  
Vol 35 (7) ◽  
pp. 65
Author(s):  
BRUCE JANCIN
Keyword(s):  
Bone Loss ◽  
Antiepileptic Drugs

FDA Panels Reject Suicidality Warning for Antiepileptic Drugs

2008 ◽  
Vol 38 (15) ◽  
pp. 5
Author(s):  
ELIZABETH MECHCATIE
Keyword(s):  
Antiepileptic Drugs
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