Effect of syringopicroside hepatocyte targeting nanopreparation on anti-duck hepatitis B virus and its safety evaluation

2021 ◽  
Vol 172 (11) ◽  
pp. 611-617
Author(s):  
X. W. Zhang ◽  
◽  
M. C. Li ◽  
J. J. Dou ◽  
◽  
...  
1988 ◽  
Vol 62 (3) ◽  
pp. 861-865 ◽  
Author(s):  
F Imazeki ◽  
K Yaginuma ◽  
M Omata ◽  
K Okuda ◽  
M Kobayashi ◽  
...  

Virology ◽  
1993 ◽  
Vol 192 (1) ◽  
pp. 217-223 ◽  
Author(s):  
Sylvie Chassot ◽  
Véronique Lambert ◽  
Alan Kay ◽  
Catherine Godinot ◽  
Bernard Roux ◽  
...  

Author(s):  
Konrad Oexle ◽  
Hubert E. Blum ◽  
Eike Walter ◽  
Wolf-Bernhard Offensperger ◽  
Silke Offensperger ◽  
...  

1991 ◽  
Vol 106 (3) ◽  
pp. 435-443 ◽  
Author(s):  
S. M. Murray ◽  
J. S. Freiman ◽  
K. Vickery ◽  
D. Lim ◽  
Y. E. Cossart ◽  
...  

SUMMARYThe efficacy of three proprietary glutaraldehyde disinfectants and their component bases was assessed using the duck hepatitis B virus (DHBV) model. Inactivation of infectivity of undiluted serum containing 106·8ID50/ml DHBV was assessed after a mixture with an equal volume of disinfectant had stood at room temperature for 10 min. A dried spill of infectious serum was simulated using sterile filter paper disks, saturated with serum containing DHBV, dried and then exposed to test disinfectant for 10 min. Residual infectivity, and hence the reduction in virus titre, was determined by inoculation of dilutions of the treated samples into 1-day-old ducklings. A greater than 3 log10reduction in virus titre could be demonstrated for the disinfectants as well as for some of their component bases. Disinfectant activity varied according to the method of viral presentation but a reduction of exposure time from 10 to 2·5 min did not diminish activity. The experimental protocol permits a comparative and quantitative assessment of the efficacy of both established and new disinfectants.


1989 ◽  
Vol 29 (4) ◽  
pp. 244-248 ◽  
Author(s):  
Hideaki Haritani ◽  
Toshikazu Uchida ◽  
Yasunori Okuda ◽  
Toshio Shikata

Intervirology ◽  
1995 ◽  
Vol 38 (6) ◽  
pp. 316-324
Author(s):  
Klaus-Hinrich Heermann ◽  
Dagmar Wagenseil ◽  
Stephan Lottmann ◽  
Wolfram H. Gerlich ◽  
Reiner Thomssen

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