Abstract
OBJECTIVE: To investigate prognostic significance of n1 and n2 station metastatic lymph node ratio(rN) after distal gastric cancer surgery. METHODS: A total of 408 patients who underwent radical distal gastrectomy (D2) under general anesthesia in 2012-2014. The critical value of rN1 and rN2 were calculated respectively. Prognostic factors were identified by univariate and multivariate analyses.RESULTS: An rN1 of 0.140 and rN2 of 0.100 was found to be the best cut-off value to determine the prognosis of patients with distal gastric cancer (p < 0.001).Univariate and multivariate analysis show that gender, age, nerves invaded, carcinoma nodules, LNS, LNS1, LNS2 were non-prognostic factors.tumor size, depth of invasion,blood vessels invaded,degree of differentiation,rN, PLNS1,rN1, PLNS2, rN2,pTNM were prognostic factors. Among prognostic factors, the partial regression coefficients were, from high to low, pTNM, rN2, rN2, rN. CONCLUSION: RN1 and RN2 is a better prognostic tool for gastric cancer patients after curative distal gastrectomy.which is a beneficial and reliable technique for evaluating lymph node metastasis.
Lymph Node Mapping in Gastric Cancer Surgery: Current Status and New Horizons
