scholarly journals ENCEFALITIS POR VIRUS HERPES HUMANO TIPO 6 EN UNA ADOLESCENTE CON LUPUS ERITEMATOSO SISTÉMICO. PRIMER CASO REPORTADO EN EL ECUADOR.

2021 ◽  
Vol 31 (2) ◽  
pp. 114-116
Author(s):  
Jhaneth Guerra Vilca ◽  
Daniel Cruz Montesinos ◽  
Wendy Mercedes Merizalde ◽  
Lorena Hidalgo Jaira ◽  
Verónica Del Pilar Villacis

The case of a fourteen-year-old patient with Systemic Lupus Erythematosus with severe activity index and immunosuppressive treatment is described. He went to the Pediatric Emergency Department of the Carlos Andrade Marín Specialty Hospital, for presenting fever, headache, nausea, auditory hallucinations and paresis in the lower extremities. Cerebrospinal fluid was studied by Polymerase Chain Reaction, in which the presence of Human Herpes Virus type 6 or also called Roseolovirus was detected. Ganciclovir was started with a favorable clinical response in 72 hours. Conclusions: The presence of HHV-6 encephalitis should be considered in immunocompromised patients with encephalopathy and use of ganciclovir as directed therapy.

2005 ◽  
Vol 160 (1) ◽  
pp. 61-65 ◽  
Author(s):  
Júnia Maria Netto Victória ◽  
André Luiz Sena Guimarães ◽  
Luciano Marques da Silva ◽  
Evanguedes Kalapothakis ◽  
Ricardo Santiago Gomez

2004 ◽  
Vol 7 (5) ◽  
pp. 533-537 ◽  
Author(s):  
Laurentia Nodit ◽  
Noriko Murase ◽  
Jorge D. Reyes ◽  
George V. Mazariegos ◽  
Rakesh Sindhi ◽  
...  

There is sparse information in humans on graft-versushost (GVH) lymphadenopathy. A 15-month-old male received a liver and small bowel transplant for short bowel after gastroschisis. At 21 days he developed a GVH-like skin rash. Flow cytometry demonstrated 16.1% circulating donor cells. Polymerase chain reaction for Epstein-Barr virus was negative. Two months later, the rash recurred with diffuse lymphadenopathy. Lymph node biopsy showed effaced architecture without visible follicles, large numbers of CD79a+ immunoblasts interspersed with smaller CD3+ and CD8+ cells, and prominent dendritic cell hyperplasia. Human herpes virus 8, cytomegalovirus, and EBER-1 probes were negative, as was polymerase chain reaction for human herpes virus 6. Allograft intestinal biopsies on days 10 and 24 had a similar infiltrate. The features appeared to be those of lymphocytes trafficking between the graft and host with a mixed lymphocyte reaction in situ, a GVH-type reaction without tissue damage. The reaction was self-limiting in the intestinal graft, and the lymphadenopathy resolved with some decrease in immunosupression. Circulating donor cells fell to 2.5% by day 62, and the child has been rejection free on low-dose immunosuppression.


2006 ◽  
Vol 24 (3) ◽  
pp. 313-320 ◽  
Author(s):  
Michael P. Glotzbecker ◽  
John P. Dormans ◽  
Bruce R. Pawel ◽  
Brian P. Wills ◽  
Yagnya Joshi ◽  
...  

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