Development of Fetoscopic and Minimally Invasive Ultrasound-guided Surgical Simulator: Part of Global Education

ABSTRACT Modern practice in perinatology involves a significant portion of invasive procedures. Training in fetal diagnostic procedures is generally accomplished using in vitro model. Fetal therapeutic procedures require a more sophisticated skill. Fetoscopic intervention is most commonly performed for laser dichorionization of the placental in twin-twin transfusion syndrome. A co-ordination between ultrasound guidance and endoscopic surgical skill is required. This article outlines the training schemes in fetal surgery, including surgical simulator (in vitro) model, animal model, and observer and hands-on training. We have described our Siriraj Fetoscopic Surgical SimulatorTM for the trainee to master his proficiency at his own time and pace. How to cite this article Wataganara T. Development of Fetoscopic and Minimally Invasive Ultrasound-guided Surgical Simulator: Part of Global Education. Donald School J Ultrasound Obstet Gynecol 2013;7(3):352-355.

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Modulation of Neural Network Activity through Single Cell Ablation: An in Vitro Model of Minimally Invasive Neurosurgery

Molecules ◽

10.3390/molecules21081018 ◽

2016 ◽

Vol 21 (8) ◽

pp. 1018 ◽

Cited By ~ 6

Author(s):

Alessandro Soloperto ◽

Marta Bisio ◽

Gemma Palazzolo ◽

Michela Chiappalone ◽

Paolo Bonifazi ◽

...

Keyword(s):

Neural Network ◽

Minimally Invasive ◽

Single Cell ◽

In Vitro Model ◽

Network Activity ◽

Minimally Invasive Neurosurgery ◽

Cell Ablation ◽

Vitro Model

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An in vitro model for the study of chemical exchange between glass ionomer restorations and partially demineralized dentin using a minimally invasive restorative technique

Journal of Dentistry ◽

10.1016/j.jdent.2011.10.016 ◽

2011 ◽

Vol 39 ◽

pp. S20-S26 ◽

Cited By ~ 12

Author(s):

Hien C. Ngo ◽

Graham Mount ◽

John McIntyre ◽

Loc Do

Keyword(s):

Minimally Invasive ◽

In Vitro Model ◽

Chemical Exchange ◽

Glass Ionomer ◽

Vitro Model ◽

Demineralized Dentin

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400: Ultrasound-Guided Catheter Insertion into an in Vitro Model: A Feasibility Study

Regional Anesthesia and Pain Medicine ◽

10.1016/j.rapm.2008.07.167 ◽

2008 ◽

Vol 33 (5) ◽

pp. e82-e82

Author(s):

H JLALA ◽

G FOXALL ◽

J FRENCH ◽

J HARDMAN ◽

N BEDFORTH

Keyword(s):

Feasibility Study ◽

In Vitro Model ◽

Catheter Insertion ◽

Ultrasound Guided ◽

Vitro Model

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400. Ultrasound-Guided Catheter Insertion into an in Vitro Model: A Feasibility Study

Regional Anesthesia and Pain Medicine ◽

10.1136/rapm-00115550-200809001-00155 ◽

2008 ◽

Vol 33 (Suppl 1) ◽

pp. e82.2-e82

Author(s):

H. Jlala ◽

G. Foxall ◽

J. French ◽

J. Hardman ◽

N. Bedforth

Keyword(s):

Feasibility Study ◽

In Vitro Model ◽

Catheter Insertion ◽

Ultrasound Guided ◽

Vitro Model

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Ultrasound-Guided Catheter Insertion into an in Vitro Model: A Feasibility Study

Regional Anesthesia and Pain Medicine ◽

10.1097/00115550-200809001-00155 ◽

2008 ◽

Vol 33 (Sup 1) ◽

pp. e82

Author(s):

H. Jlala ◽

G. Foxall ◽

J. French ◽

J. Hardman ◽

N. Bedforth

Keyword(s):

Feasibility Study ◽

In Vitro Model ◽

Catheter Insertion ◽

Ultrasound Guided ◽

Vitro Model

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An in vitro model for investigation of vitamin A effects on wound healing

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000692 ◽

2021 ◽

pp. 1-6

Author(s):

Hoda Keshmiri Neghab ◽

Mohammad Hasan Soheilifar ◽

Gholamreza Esmaeeli Djavid

Keyword(s):

Wound Healing ◽

Endothelial Cell ◽

Vitamin A ◽

In Vitro Model ◽

Cellular Proliferation ◽

Endothelial Cell Migration ◽

Normal Fibroblast ◽

Anti Inflammatory ◽

Vitro Model

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inﬂammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inﬂammation responses.

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