Placental Doppler Microvasculature in Normal and Abnormal Pregnancy

1. The family histories of 30 patients with idiopathic developmental retardation were analyzed with respect to pregnancy records of nonaffected female kindred. Comparison was made with data from the family histories of 27 similarly ascertained control patients. 2. The mothers and maternal aunts of retardates were found to have abnormal pregnancy records, i.e., a markedly decreased reproductive rate and increased fetal loss (reproductive failure). Similar findings were not noted in the histories of the maternal grandmothers or other females in the families. 3. The comparison study suggests genetic factors as an influence on reproduction in the maternal families of retardates but their nature remains unknown. 4. The utilization of these findings in clinical genetic counseling is briefly discussed.

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The Vascular Supply of the Placenta in Normal and Abnormal Pregnancy

Pathology of the Female Genital Tract ◽

10.1007/978-1-4757-6143-6_31 ◽

1977 ◽

pp. 673-690 ◽

Cited By ~ 1

Author(s):

John Bonnar ◽

B. L. Sheppard

Keyword(s):

Vascular Supply ◽

Abnormal Pregnancy

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Fibrinogen levels helps in early detection of abnormal pregnancies

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20164665 ◽

2016 ◽

Vol 6 (1) ◽

pp. 232 ◽

Cited By ~ 1

Author(s):

Kanchana A. ◽

Girijavani DSS

Keyword(s):

Early Diagnosis ◽

Andhra Pradesh ◽

Private Hospital ◽

Fetal Death ◽

Total Proteins ◽

Missed Abortion ◽

Abruptio Placentae ◽

Abnormal Pregnancy ◽

Pregnancy Induce Hypertension ◽

D Dimer

Background: Haemostatic failure as an end result of various complications of pregnancy is an important cause of maternal mortality in India. The main aim of this study is to detect the levels of fibrinogen in abnormal pregnancy i.e. Pregnancy induce hypertension (PIH), Intra uterine fetal death (IUFD), Missed abortion, Abruptio placenta.Methods: Study was conducted on 150 in patients joined in Obstetrics ward private hospital, Andhra Pradesh, 50 are control subjects and 100 are study patients, Out of hundred (100) cases, 40 are PIH, 25 are IUFD, 25 are Missed abortion, and 10 are Abruptio placentae. Estimated for fibrinogen, D-Dimer, total proteins, Albumin.Results: The fibrinogen levels in present study decreased significantly. PIH (Control mean 442.0, S.D ±43.38, Test mean 296.0, S.D ±48.03, p<0.001). IUFD (Control mean 442.0, S.D±43.38, Test mean 262.4, S.D±20.06, p<0.001). Missed abortion (Control mean 442.0, S.D ±43.38, Test mean 250.80, S.D±26.13, p<0.001). Abruptio placentae (Control mean 442.0, S.D±43.38, Test mean 210.5, S.D±87.38, P<0.001). D-dimer levels are estimated semi quantitatively and the levels were found to be increased. Total proteins and albumin are decreased in all the cases, but significantly in PIH (T.P-Control mean6.25, S.D±0.65, Test mean 5.25, S.D±1.57, p<0.001, Albumin- Control mean 2.79, S.D±0.34, Test mean 2.23, S.D±0.59, p<0.001).Conclusions: The estimation of plasma fibrinogen is helpful not only in the early diagnosis of haemostatic failure but also to guide replacement therapy during the fibrinopenic state.

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