scholarly journals Curcumin Containing Soft Liner as an Alternative Treatment Modality for Oral Candidiasis

2021 ◽  
Vol 12 (6) ◽  
pp. 435-440
Author(s):  
Neven S Aref ◽  
Reham M Abdallah
2012 ◽  
Vol 76 (10) ◽  
pp. 1526-1527 ◽  
Author(s):  
Yazeed Alghonaim ◽  
Rickul Varshney ◽  
Noah Sands ◽  
Sam J. Daniel

2012 ◽  
Vol 10 (4) ◽  
pp. 310-314 ◽  
Author(s):  
David F. Jimenez ◽  
Constance M. Barone

Patients with Apert syndrome commonly present with ocular proptosis due to bilateral coronal craniosynostosis and midfacial hypoplasia. Severe proptosis can cause visual compromise and damage, which is most commonly treated with bilateral orbital frontal advancement. The authors present the case of a patient who was treated at 8 weeks of age with endoscope-assisted bilateral coronal craniectomies followed by treatment with a custom-made postoperative cranial orthosis. The patient underwent the procedure without any complications. Over the ensuing months, the patient's proptosis corrected, the forehead and orbital rims advanced without the need for an orbital frontal advancement and craniotomies. This approach may provide an alternative treatment modality for these patients.


Author(s):  
Manoj Humagain ◽  
Asmita Dawadi

Periodontal plastic or aesthetic surgery by its definition comprises of surgical procedures performed to correct or eliminate anatomic, developmental or traumatic deformities of the gingiva or oral mucosa. ‘Perfect smile’ has been the common desire of many people in this era. Smile has significant role in the expression, appearance and in the development of self-esteem. Excessive gingival display, which is commonly termed as ‘gummy smile’ will adversely affects smile aesthetics and is therefore undesirable to many people. It is one of the several developmental or acquired deformities and conditions that manifest in the periodontium. Different literature reveals common consensus on considering gingival display of greater than 3 mm is gummy smile and is unaesthetic. Lip repositioning surgery has been establishing as a promising less invasive alternative treatment modality in aesthetic rehabilitation for the cases of excessive gingival display. Perseverance and application of such technique shall provide many more a horizon to this young but highly imaginative and creative technique in periodontal therapy to charter.


2015 ◽  
Vol 26 (2) ◽  
pp. S19
Author(s):  
Hong-Ray Chen ◽  
Seng-Tang Wu ◽  
Tai-Lung Cha ◽  
Guang-Haun Sun ◽  
Dah-Shyong Yu ◽  
...  

2013 ◽  
Vol 15 (5) ◽  
pp. 266-270 ◽  
Author(s):  
Zekayi Kutlubay ◽  
Abdullah Songur ◽  
Burhan Engіn ◽  
Rashid Khatіb ◽  
Özden Calay ◽  
...  

1976 ◽  
Vol 6 (2) ◽  
pp. 165-170
Author(s):  
Robert B. Kahn ◽  
Norman T. Schramm ◽  
Fawzi Daoud

In May, 1974, Fresno County's Narcotic Abuse Treatment Program began a twenty-one-day outpatient methadone detoxification treatment modality. This short-term detoxification treatment was offered in addition to the maintenance program begun in November, 1973. During the course of its operation, an on-going evaluation of the program was accomplished to assess the efficacy of further utilization of this expensive and difficult treatment modality [1]. The results of the evaulation suggested an alternative treatment modality [2]. A ninety-day contractual detoxification program was offered to a group of patients who were eligible for admission to the maintenance program. The purpose of this paper is to examine this alternative treatment modality, its characteristics, its therapeutic outcomes and the rationale for its use.


2021 ◽  
Author(s):  
Hoang Nguyen ◽  
Hannah Wilson ◽  
Sahana Jayakumar ◽  
Viraj Kulkarni ◽  
Smita Kulkarni

Recently discovered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas13 proteins are programmable RNA-guided ribonucleases that target single-stranded RNA (ssRNA). CRISPR/Cas13 mediated RNA targeting has emerged as a powerful tool for detecting and eliminating RNA viruses. Here, we demonstrate the effectiveness of CRISPR/Cas13d to inhibit HIV-1 replication. We designed guide RNAs (gRNAs) targeting highly conserved regions of HIV-1. RfxCas13d (CasRx) in combination with HIV-specific gRNAs efficiently inhibited HIV-1 replication in cell line models. Furthermore, simultaneous targeting of four distinct sites in the HIV-1 transcript resulted in robust inhibition of HIV-1 replication. We also show the effective HIV-1 inhibition in primary CD4+ T-cells and suppression of HIV-1 reactivated from latently infected cells using the CRISPR/Cas13d system. Our study demonstrates the utility of the CRISPR/Cas13d nuclease system to target acute and latent HIV infection and provides an alternative treatment modality against HIV.


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