Fibroblasts and Phagocytic Cells in Phenytoin-induced Connective Tissue Proliferation

2012 ◽  
Vol 2 ◽  
pp. 113-120
Author(s):  
Rosaiah Kanaparthy ◽  
Aruna Kanaparthy ◽  
Kamala Devi
Keyword(s):  
Connective Tissue ◽  
Phagocytic Cells ◽  
Tissue Proliferation

scholarly journals Antioxidants the Powerful New Weapons in the Fight Against Periodontal Diseases

2013 ◽  
Vol 01 (02) ◽  
pp. 085-090 ◽  
Author(s):  
Baljeet Singh ◽  
Shivani Bhickta ◽  
Rajesh Gupta ◽  
Sachin Goyal ◽  
Ram Gupta
Keyword(s):  
Reactive Oxygen Species ◽  
Free Radicals ◽  
Connective Tissue ◽  
Chronic Inflammation ◽  
Inflammatory Cell ◽  
Periodontal Diseases ◽  
Polymorphonuclear Leucocyte ◽  
Oxygen Species ◽  
Phagocytic Cells ◽  
Extracellular Release

AbstractThe human inflammatory periodontal diseases are amongst the most common of chronic diseases. The predominant inflammatory cell (96%) within the healthy connective tissue and epithelium of the gingiva is polymorphonuclear leucocyte (PMNL). Periodontopathic bacteria in the gingivomucosal tissue may functionally activate PMNLs leading to an increased production of reactive oxygen species (ROS). Chronic inflammation subjects the nearby cells to elevated levels of free radicals (ROS) due to extracellular release from phagocytic cells. Antioxidants block the process of oxidation by neutralizing free radicals. In doing so, the antioxidant themselves become oxidized. Because of this, there is a constant need to replenish our antioxidant resources.

Intracellular formation of calcium concretions by phagocytic cells in freshwater mussels

1989 ◽  
Vol 67 (1) ◽  
pp. 198-207 ◽  
Author(s):  
Harold Silverman ◽  
Pamela E. Richard ◽  
Russell H. Goddard ◽  
Thomas H. Dietz
Keyword(s):  
Connective Tissue ◽  
Colloidal Gold ◽  
Synthetic Activity ◽  
Stereo Pair ◽  
Phagocytic Cells ◽  
India Ink ◽  
Transmission Electron ◽  
Tissue Cells ◽  
Endocytic Activity ◽  
Endocytic Vesicles

The gills of freshwater unionid mussels contain large accumulations of extracellular calcium phosphate concretions. Connective tissue cells located in specific areas in the gills of these animals are the site of concretion formation. The cell type responsible for concretion formation appears to differentiate from an undifferentiated precursor cell by accumulating endocytic vesicles and producing amorphous membrane-bound granules from active rough endoplasmic reticulum and Golgi apparatus. In the most mature of the cells, these granules occupy most of the cytoplasm. Concretions are initiated within the amorphous granules as observed using stereo-pair transmission electron microscopy. These connective tissue cells exhibit phagocytosis, and can ingest India ink particles and colloidal gold. Colloidal gold is internalized through an endocytic mechanism within vesicles. Gold can be observed in the amorphous granules, implying fusion of such endocytic vesicles with the amorphous granules. While the exact mechanism of concretion formation is not understood, the cellular site of formation has been identified. Further, protein synthetic activity as well as endocytic activity appear necessary for concretion production.

Myxobolid parasites (Myxozoa: Myxobolidae) infecting fishes of western Montana, with notes on histopathology, seasonality, and intraspecific variation

1989 ◽  
Vol 67 (8) ◽  
pp. 1915-1922 ◽  
Author(s):  
Lawrence G. Mitchell
Keyword(s):  
Connective Tissue ◽  
Western Montana ◽  
Infection Prevalence ◽  
Tissue Proliferation ◽  
Prosopium Williamsoni ◽  
Catostomus Macrocheilus ◽  
Redside Shiner ◽  
Richardsonius Balteatus ◽  
Cyst Rupture ◽  
Longnose Sucker

Cypriniform and salmonid fishes of the Columbia River drainage of western Montana harbor five members of the myxozoan family Myxobolidae. Myxobolus muelleri inhabits Ptychocheilus oregonensis (northern squawfish), Mylocheilus caurinus (peamouth), Richardsonius balteatus (redside shiner), and Catostomus macrocheilus (largescale sucker). Cysts appeared in gills, musculature, subcutis, and visceral mesenteries. Unencysted spores infiltrated mesenteries and viscera. Spore size and shape in the various tissues and hosts were highly varied. Muscle and subcutaneous cysts were associated with connective tissue proliferation and muscle degeneration; cyst rupture was associated with diffuse inflammation and rodlet cell proliferation. Infection prevalence in muscles and kidneys was high in adult and juvenile hosts (78–100%) throughout the year. Seasonal prevalence of gill and subcutaneous infections fluctuated markedly. Cysts of Myxobolus dujardini occurred in gills of the northern squawfish, peamouth, and redside shiner. Unicauda sp. was found in the eye capsule, gall bladder, mesenteries, and kidney of northern squawfish. Henneguya zschokkei occurred in intermuscular connective tissue of Prosopium coulteri (pygmy whitefish) and Prosopium williamsoni (mountain whitefish). Myxobolus sp. occurred in the gills of Catostomus catostomus (longnose sucker).

scholarly journals Histological analysis of state of tissues in internal organs of black-backed shad Alosa kessleri kessleri

2017 ◽  
Vol 188 (1) ◽  
pp. 155-161
Author(s):  
Maria P. Grushko ◽  
Nadezhda N. Fedorova ◽  
Alina A. Aitimova
Keyword(s):  
Connective Tissue ◽  
Environmental Pollution ◽  
Histological Analysis ◽  
Internal Organs ◽  
Common Features ◽  
Tissue Proliferation ◽  
Wide Range ◽  
Negative Impacts

Internal organs of black-backed shad are examined by histological analysis. Wide range of pathologies is found, which are supposedly caused by chronic environmental pollution. The pathologies of tissue and cellular levels have common features but various symptoms, as edema, hemorrhage, necrosis, inflammation, connective tissue proliferation, proliferative changes in the epithelium. The gills, liver; kidney, and intestines are the most sensitive to negative impacts of environments.

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