scholarly journals Spectrophotometric Analysis of Saliva for Metal Ion Release in Patients Prior to and After Cementation of Cobalt Chromium or Nickel-Chromium Alloy Crowns: An in Vivo Study

2018 ◽  
Vol 8 (2) ◽  
pp. 92-96
Author(s):  
Sabita M Ram ◽  
Jyoti B Nadgere ◽  
Naisargi P Shah ◽  
Bhoomi A Parmar
2011 ◽  
Vol 34 (1) ◽  
pp. 126-130 ◽  
Author(s):  
F. Amini ◽  
A. Jafari ◽  
P. Amini ◽  
S. Sepasi

2011 ◽  
Vol 26 (3) ◽  
pp. 209-214 ◽  
Author(s):  
Micéli Guimarães Blaya ◽  
Diego Segatto Blaya ◽  
Paola Mello ◽  
Érico M. M Flores ◽  
Luciana M. Hirakata

2015 ◽  
Vol 114 (4) ◽  
pp. 602-608 ◽  
Author(s):  
Maria Claudia Lucchetti ◽  
Giovanni Fratto ◽  
Federica Valeriani ◽  
Elisabetta De Vittori ◽  
Saverio Giampaoli ◽  
...  

2021 ◽  
pp. 030157422110373
Author(s):  
Prasad Chitra ◽  
GS Prashantha ◽  
Arun Rao ◽  
Harshvardhan S Jois

Introduction: Fluoride agents to prevent white spot lesions are used often during orthodontic treatment. The beneficial effects of fluoride, when consumed within permissible limits on dental structures, are well known. Their implications on underlying biological tissues, however, are unknown. Mouthwashes and dentifrices with fluorides are associated with metal ion release into the mouth with possible cell genotoxicity. Since these cariostatic agents are frequently used during orthodontic therapy, a deeper understanding of the effects of fluoride on oral tissues was considered necessary. Methodology: Three groups of patients (30 each)—group 1 (untreated controls), group 2 (non-fluoridated), and group 3 (Fluoridated) were analyzed. Patients in groups 2 and 3 were bonded with the same bracket prescription and treated with similar archwire sequences. Buccal mucosal cells at 4 specific time periods (before treatment, 1 week, 30 days, and 6 months) were collected, using a wooden tongue depressor, and assessed for any nuclear abnormalities. Comparisons of changes were made with an untreated control group and also between the non-fluoridated and fluoridated groups. Relevant conclusions were drawn after analysis of the results. Results: Greater number of nuclei were observed at the 30-day time interval in the fluoridated group, which was statistically significant at P < .001. Conclusion: Use of fluoridated oral hygiene products in patients undergoing fixed orthodontic treatment with NiTi archwires could increase the risk of micronuclei formation in buccal mucosal cells.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sung-Hyun Kim ◽  
Jin Hee Lee ◽  
Kikyung Jung ◽  
Jun-Young Yang ◽  
Hyo-Sook Shin ◽  
...  

Human skins are exposed to nanomaterials in everyday life from various sources such as nanomaterial-containing cosmetics, air pollutions, and industrial nanomaterials. Nanomaterials comprising metal haptens raises concerns about the skin sensitization to nanomaterials. In this study, we evaluated the skin sensitization of nanomaterials comparing metal haptens in vivo and in vitro. We selected five metal oxide NPs, containing copper oxide, cobalt monoxide, cobalt oxide, nickel oxide, or titanium oxide, and two types of metal chlorides (CoCl2 and CuCl2), to compare the skin sensitization abilities between NPs and the constituent metals. The materials were applied to KeratinoSensTM cells for imitated skin-environment setting, and luciferase induction and cytotoxicity were evaluated at 48 h post-incubation. In addition, the response of metal oxide NPs was confirmed in lymph node of BALB/C mice via an in vivo method. The results showed that CuO and CoO NPs induce a similar pattern of positive luciferase induction and cytotoxicity compared to the respective metal chlorides; Co3O4, NiO, and TiO2 induced no such response. Collectively, the results implied fast-dissolving metal oxide (CuO and CoO) NPs release their metal ion, inducing skin sensitization. However, further investigations are required to elucidate the mechanism underlying NP-induced skin sensitization. Based on ion chelation data, metal ion release was confirmed as the major “factor” for skin sensitization.


Sign in / Sign up

Export Citation Format

Share Document