Rhesus Incompatibility

2009 ◽  
pp. 413-413
Author(s):  
Annamma Jacob
Author(s):  
Nasenien Nourkami-Tutdibi ◽  
Martina Geipel ◽  
Gabriele Meyberg-Solomayer ◽  
Zoltan Takacs ◽  
Sascha Meyer

SummarySignificant progress in prenatal care has decreased the incidence of rhesus incompatibility, which may result in hemolytic disease of the fetus and newborn (HDFN). This case report describes an unusual presentation of HDFN in a preterm infant delivered by caesarean section with isolated massive abdominal fluid collection as the leading clinical sign in addition to severe anemia. The immediate drainage of ascites provided transient clinical stabilization with improved pulmonary function in the delivery suite. After admission to the neonatal intensive care unit (NICU), HDFN treatment was initiated. This case report shows the importance of adequately trained staff including neonatologists, pediatricians and NICU nurses in the delivery suite to provide neonatal intensive care for HDFN.


1977 ◽  
Vol 15 (22) ◽  
pp. 88-88

Consumers’ Association has just published a revised and up-to-date edition of this comprehensive guide to pregnancy and childbirth. The book is a straightforward account for women of what should happen when all goes well, and also deals with what might happen if anything goes wrong; it gives information on rhesus incompatibility, threatened miscarriage, toxaemia, rubella and other infectious diseases in pregnancy, and advises on how to cope with a stillbirth. Types of anaesthesia and pain-relieving drugs, methods of assisted births and caesarean section are described. Apart from medical aspects, Pregnancy Month by Month explains what financial benefits are available and how and when to claim them.


Brain ◽  
1955 ◽  
Vol 78 (4) ◽  
pp. 514-536 ◽  
Author(s):  
LEONARD CROME ◽  
BRIAN H. KIRMAN ◽  
MARGARET MARRS

1967 ◽  
Vol 12 (11) ◽  
pp. 415-417
Author(s):  
Margaret W. Macgregor

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 5745-5745
Author(s):  
Usama Gergis ◽  
Naima Ali Al-Mulla ◽  
Segovia Javier ◽  
Rania Hafez ◽  
Adrienne A. Phillips ◽  
...  

Abstract Background: Transfusion needs after allogeneic transplantation are closely associated with morbidity, cost of transplantation and may also be associated with long-term outcome. In an effort to better predict determinants of recovery after reduced intensity conditioning, we analyzed 214 consecutive patients who received allogeneic hematopoietic stem cell transplantation (HSCT) at our institution from January 2012 to December 2013. Patients and Methods: We excluded patients who experienced early (in the first 4 months) relapse (n=28), non-relapse mortality (n=28) or who experienced prolonged hospital stay before day 100 for transplant related complications (n=51). One hundred and seven patients had uneventful recovery until day 100 and met the inclusion criteria. The majority of patients received Fludarabine and melphalan conditioning (87%). Approximately one third each of the patients had HLA-identical related, HLA-matched unrelated donors or underwent haplo-cord transplantation. Recipients of HLA-identical related or unrelated donor transplant received alemtuzumab and post-transplant tacrolimus. Haplo-cord recipients received thymoglobulin and post-transplant tacrolimus and mycophenolate. Patients and transplant characteristics are summarized in table 1. T-tests were used for comparison between groups. Results: In our analysis of 107 patients who underwent T cell depleted allogeneic transplantation and fared well at day 100, the determinants of prolonged anemia were ABO incompatibility (p=0.006), rhesus incompatibility (p=0.01) and acute graft versus host disease (aGVHD) (p=0.02). Whereas prolonged thrombocytopenia was only associated with the development of any grade aGVHD (p=0.04). At day 100, the hematopoietic recovery of haplo-cord grafts is similar to matched related and unrelated grafts. Conclusion: ABO incompatibility, rhesus incompatibility and occurrence of acute graft vs host disease are the major determinants of red blood cell recovery. Occurrence of acute graft vs host disease is a major determinant of platelet recovery. Of interest, the use of umbilical cord blood grafts combined with haplo-identical grafts is associated with recovery of red blood cells and platelets that is similar to that of adult donor grafts. Disclosures No relevant conflicts of interest to declare.


2000 ◽  
Vol 3 (9) ◽  
pp. 294-296
Author(s):  
R Ghani ◽  
MR Said ◽  
IY Hussein ◽  
BE Teague ◽  
E Stewart

Induction of labour (IOL) is the artificial initiation of uterine contraction prior to their spontaneou onset, leading to progressive dilatation, effacement of the cervix and delivery of the baby. The purpose of induction is to achieve benefit to the health of the mother and/or baby, greater than if the pregnancy continued. In recent years, the major fetal and maternal indications for IOL have not altered greatly. They still include prolonged pregnancy, pre-eclampsia, dysmaturity, antepartum haemorrhage, gross fetal abnormality, rhesus incompatibility, diabetes mellitus and fetal death in utero. In the UK the commonest indication is prolonged pregnancy. In addition, IOL is often performed now for cumulative indications, any of which if considered in isolation would probably constitute an insufficient reason: for example, increasing maternal age, previous infertility, poor obstetric history. Whatever the indication for induction it is essential that gestational age is calculated accurately. The rate of induction varies widely in different unit , and between individual obstetricians within the same unit.


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