scholarly journals First report on extended distance between tumor lesion and adjacent organs at risk using interventionally applied balloon catheters: a simple procedure to optimize clinical target volume covering effective isodose in interstitial high-dose-rate brachytherapy of liver malignomas

2019 ◽  
Vol 11 (2) ◽  
pp. 152-161 ◽  
Author(s):  
Peter Hass ◽  
Ingo G. Steffen ◽  
Maciej Powerski ◽  
Konrad Mohnike ◽  
Max Seidensticker ◽  
...  
2020 ◽  
Vol 51 (3) ◽  
pp. S6-S7
Author(s):  
Vivian Truong ◽  
Emilia Timotin ◽  
Tom Farrell ◽  
Kevin Diamond

Author(s):  
Fan Liang ◽  
Bryan Traughber ◽  
Raymond Musiz ◽  
Rodney Ellis ◽  
Tarun K. Podder

Brachytherapy is one the most effective treatment modalities for both gynecological (GYN) cancer and prostate cancer. The clinical outcome of brachytherapy, both high-dose-rate (HDR) and low-dose-rate (LDR), depends on the precision of the desired or planned dose distribution and delivery. In HDR procedure, the accuracy of reconstruction of catheters or needles (e.g. Syed catheter or Simon-Heyman capsule for GYN or needles for prostate) from CT images can significantly affect the accuracy of dose distribution in the treatment (dosimetric) plan, which can result in unwanted clinical outcome. In current practice, an authorized medical physicist manually reconstructs the catheters or needles for dosimetric plan, which determines the position and dwell time for the radiation source for delivering the prescription dose to the target volume sparing organs at risk (OARs) as much as possible. It is not only challenging but also time consuming for reconstructing all the catheters or needles (ranging 15–20) manually, slice-by-slice in CT images. As shown in Fig. 1, the needles on the right (HDR catheters) have created so much artifacts in CT images that it is almost impossible to reconstruct those applicators (catheters/ needles) manually. Additionally, the reconstruction can be operator dependent and can be inaccurate and inconsistent. In this study, we have investigated the applicability of electromagnetic (EM) sensor-based navigation for fast and accurate reconstruction of HDR catheters and needles.


Brachytherapy ◽  
2016 ◽  
Vol 15 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Grant Harmon ◽  
Bonnie Chinsky ◽  
Murat Surucu ◽  
Matthew Harkenrider ◽  
William Small

2018 ◽  
Vol 52 (4) ◽  
pp. 461-467
Author(s):  
Hironori Akiyama ◽  
Csilla Pesznyák ◽  
Dalma Béla ◽  
Örs Ferenczi ◽  
Tibor Major ◽  
...  

Abstract Background The aim of the study was to present dosimetric comparison of image guided high-dose-rate brachytherapy (IGBT) with volumetric modulated arc therapy (VMAT) for head and neck cancer regarding conformity of dose distribution to planning target volume (PTV) and doses to organs at risk (OARs). Patients and methods Thirty-eight consecutive patients with T1-4 mobile tongue, floor of mouth and base of tongue cancer treated with IGBT were selected. For these patients additional VMAT treatment plans were also prepared using identical computed tomography data. OARs and PTV related parameters (e.g. V98, D0.1cm3, Dmean, etc.) were compared. Results Mean V98 of the PTV was 90.2% vs. 90.4% (p > 0.05) for IGBT and VMAT, respectively. Mean D0.1cm3 to the mandible was 77.0% vs. 85.4% (p < 0.05). Dmean to ipsilateral and contralateral parotid glands was 4.6% vs. 4.6% and 3.0% vs. 3.9% (p > 0.05). Dmean to ipsilateral and contralateral submandibular glands was 16.4% vs. 21.9% (p > 0.05) and 8.2% vs. 16.9% (p < 0.05), respectively. Conclusions Both techniques showed excellent target coverage. With IGBT dose to normal tissues was lower than with VMAT. The results prove the superiority of IGBT in the protection of OARs and the important role of this invasive method in the era of new external beam techniques.


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