scholarly journals Diagnosis and conservative treatment of adolescent idiopathic scoliosis

2021 ◽  
Vol 64 (11) ◽  
pp. 734-742
Author(s):  
Jae Hyuk Yang ◽  
Dong-Gune Chang ◽  
Seung Woo Suh

Background: Adolescent idiopathic scoliosis (AIS) has a diagnosis rate of 3% to 5% per year, but the number of cases requiring surgical treatments is very small, accounting for only 0.17% to 1.75% of all AIS patients. Most patients with AIS are diagnosed, treated, and managed in outpatient clinics.Current Concepts: AIS is a disease that occurs more frequently, and progresses faster, in females than in males. Scoliosis deformity can occur due to various causes. To differentially diagnose AIS, it is necessary to perform careful physical examinations, investigate family history, and check for neurological, growth, and developmental abnormalities. Definitive diagnosis of AIS can be performed through radiographic imaging. In the case of atypical curvature and symptoms, examinations such as magnetic resonance imaging could be required in addition to radiographic imaging. Treatment of AIS patients in outpatient clinics can be performed through observation, exercise, and orthosis. The selection and application of treatment methods and the termination period of the treatments are complexly affected by the age at the time of diagnosis; pattern, location and size of the curve; and growth potential.Discussion and Conclusion: AIS is a disease in which good results can be obtained with conservative treatments such as exercise and orthosis, which is generally applied in an outpatient setting. To properly treat AIS, it is necessary to have an in-depth understanding of the characteristics of AIS, timing of treatment, and factors influencing treatment.

Spine ◽  
2013 ◽  
Vol 38 (7) ◽  
pp. 576-580 ◽  
Author(s):  
Christopher Diefenbach ◽  
Baron S. Lonner ◽  
Joshua D. Auerbach ◽  
Neil Bharucha ◽  
Laura E. Dean

2019 ◽  
Vol 21 (4) ◽  
pp. 253-260
Author(s):  
Radoslav Zamborský ◽  
Boris Liščák ◽  
Martin Trepáč ◽  
Andrey Švec ◽  
Ľuboš Danisovič

Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine mainly affecting the younger population. Earlier detection of the disorder leads to appropriate treatment and better outcomes, thus avoiding highly invasive surgical treatments. The currently available tests for the disease identification have lost their reliability and validity with time. In the past few decades, efforts have been directed towards developing a highly reliable prognostic test for AIS. Towards this end, several strategies have been employed including biochemical, biomechanical and gene-based tests. Among the three, the gene-based technology has received much attention in recent past. Notably, this is due to the fact that the human genome project, followed by genome-wide association studies (GWAS), facilitated the identification of candidate genes for disorders like AIS. Several promising biomarker genes have been identified. However, their global validations were disappointing as these genes were shown to be limited to a particular group of people/ethnicities. Such observations limit the development of a reliable global molecular/biochemical test for AIS. The currently used AIS ScoliScoreTM also has several limitations. With continued disappointments in the identification of biomarkers for AIS and lack of appropriate tests, researchers have diverted their efforts towards several alternative avenues. A ray of hope is emerging from recent observations on the association of non-coding microRNAs and epigenetic factors that might arise as future reliable markers for AIS, thus paving the way for appropriate clinical management of this disorder.


Spine ◽  
1991 ◽  
Vol 16 (7) ◽  
pp. 761-763 ◽  
Author(s):  
MAJ ALFRED E. GEISSELE ◽  
LTC MARK J. KRANSDORF ◽  
MAJ CARL A. GEYER ◽  
MAJ JAMES S. JELINEK ◽  
LTC BRUCE E. VAN DAM

Spine ◽  
2019 ◽  
Vol 44 (19) ◽  
pp. 1356-1363
Author(s):  
Kwong Hang Yeung ◽  
Gene Chi Wai Man ◽  
Lin Shi ◽  
Steve Cheuk Ngai Hui ◽  
Chileka Chiyanika ◽  
...  

2020 ◽  
Vol 9 (1) ◽  
pp. 67-73
Author(s):  
Rafael Garcia de Oliveira ◽  
Alex Oliveira de Araújo ◽  
Cícero Ricardo Gomes

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