scholarly journals Diffuse type of pigmented villonodular synovitis of knee masquerading as a soft tissue sarcoma

Biomedicine ◽  
2020 ◽  
Vol 40 (3) ◽  
pp. 405-408
Author(s):  
Bhat Shubha P. ◽  
Singh Vartika ◽  
Srinivas Teerthanath ◽  
Shetty Siddharth M. ◽  
Hosapatna Laxminarayana Kishan Prasad ◽  
...  

Pigmented villonodular synovitis (PVNS) is a rare benign neoplasm involving the synovial joints and tendon sheaths. It can be classified into localised and diffuse type. The diffuse type of PVNS is larger and very aggressive, clinically mimicking as soft tissue sarcoma. Radiological investigation can aid in knowing the relation of the mass to the joint cavity and invasion of surrounding structures. A biopsy can pose a diagnostic challenge for  pathologists. Surgical excision is the treatment of choice. Histopathological examination is necessary for a definite diagnosis. Keywords: Pigmented villonodular synovitis; diffuse; soft tissue sarcoma; histopathology.

2006 ◽  
Vol 14 (1) ◽  
pp. 76-80 ◽  
Author(s):  
MKS Lee ◽  
PFM Choong ◽  
PJ Smith ◽  
GJ Powell ◽  
JL Slavin ◽  
...  

2018 ◽  
Vol 32 (04) ◽  
pp. 322-330 ◽  
Author(s):  
Andrea Evenski ◽  
James Stensby ◽  
Samuel Rosas ◽  
Cynthia Emory

AbstractIntra-articular (IA) and peri-articular (PA) tumors of the knee are frequently encountered by orthopaedic surgeons. Nonetheless, due to the possibility of great morbidity and potential mortality, it is important to recognize and differentiate between benign and malignant lesions in a timely manner. Therefore, the purpose of this article is to provide a concise, practical, and updated review of commonly encountered IA and PA tumors including intratendinous gout, synovial chondromatosis, schwannoma, pigmented villonodular synovitis, and synovial sarcoma, and a detailed description of differentiating features to include various imaging modalities.


SICOT-J ◽  
2020 ◽  
Vol 6 ◽  
pp. 48
Author(s):  
Tarun Goyal ◽  
Souvik Paul ◽  
Arghya Kundu Choudhury ◽  
Tushar Kalonia

Introduction: Chronic synovitis involving a single large joint remains a diagnostic dilemma. We present 61 cases of chronic synovitis of the knee, followed prospectively for 2 years. The study focuses on the diagnosis, management, and histopathological correlation. Methods: We prospectively studied 61 patients with chronic mono-articular synovitis of the knee joint, between July 2016 and September 2017. All patients underwent plain radiographs, magnetic resonance imaging, and arthroscopic examination with synovial biopsy. Further treatment was based on findings of histopathological examination. Results: The average duration of symptoms was 7.72 ± 4.34 months. The mean age at presentation was 29.93 ± 15.56 years. Results of histopathological examination showed chronic nonspecific inflammation in 28 patients (46%), features suggesting tubercular infection in 19 patients (31%), pigmented villonodular synovitis in seven patients (11.5%), rheumatoid arthritis in three (5%) patients, acute inflammation in three (5%) patients and findings suggestive of synovial chondromatosis in one (1.5%) patient. Treatment was based on histopathological results. Intra-articular injections of methylprednisolone (80 mg depot preparation) were given to all patients with nonspecific synovitis and rheumatoid arthritis. Anti-tubercular treatment was started for patients with tubercular synovitis. Complete arthroscopic/open synovectomy followed by radiotherapy was carried out for patients with pigmented villonodular synovitis. Non-steroidal anti-inflammatory drugs are used for patients with acute on chronic inflammation. All patients had symptomatic relief and functional improvement in further follow-up. Discussion: Histopathological reporting remains the mainstay for diagnosis. The various differentials should always be kept in mind when approaching patients with chronic mono-articular synovitis. Specific treatment can be started once the diagnosis is confirmed.


Author(s):  

Background: PVNS is a rare, benign & aggressive disorder arising from either synovial joints or tendon sheaths; it may erode articular structures and bones. We present a case with unique features of PVNS being extra-synovial and by this report we open a gate for more researches in this field. Case Presentation: This case report concerns a 35-year-old female with a history of right knee pain for 6-month duration proceeded by gradual swelling over posterior aspect of the knee, she denies any history of trauma, clinical examination was unremarkable but apart from tenderness over the infrapatellar region with full flexion. MRI shows a heterogenous signal extra-articular and extra-synovial lesion in posterior aspect of the knee suggesting Pigmented Villonodular Synovitis, FNA revealed a hemosiderin-laden macrophages and multinucleated giant cells, Tru-cut biopsy result was suggesting PVNS as synovial cells were seen admixed with hemosiderin-laden macrophages with fibroblastic elements. Through posterior approach; the lesion was surgically excised and histopathological examination confirmed the diagnosis, the lesion was recurrent after 1-year and MRI revealed the same features, the lesion was excised by arthroscopic intervention. Conclusion: We concluded that PVNS cannot be excluded when extra-synovial lesion is assessed, and further researches on this topic will expand our understanding of the etiological and pathological aspects of this tumor.


2021 ◽  
Vol 09 (03) ◽  
pp. 346-349
Author(s):  
Mohsen Samy Barsoum ◽  
May Gamal Ashour ◽  
Emad Mohsen Barsoum ◽  
Nouran Mohamed Roby

Diffuse type tenosynovial giant cell tumor (D-TGCT) is a locally aggressive benign proliferation. Knee joint is the most commonly affected site. We present a case report with a 16 months follow up after recurrent surgery and postoperative radiotherapy.


2013 ◽  
Vol 95-B (3) ◽  
pp. 384-390 ◽  
Author(s):  
J. D. Stevenson ◽  
A. Jaiswal ◽  
J. J. Gregory ◽  
D. C. Mangham ◽  
G. Cribb ◽  
...  

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