scholarly journals Extra-synovial Pigmented Villonodular Synovitis of the knee joint, Case Repor

2021 ◽  
pp. 192
Author(s):  
Keyword(s):  
Histopathological Examination ◽  
Giant Cells ◽  
Pigmented Villonodular Synovitis ◽  
Villonodular Synovitis ◽  
Biopsy Result ◽  
Posterior Aspect ◽  
Case Presentation ◽  
History Of ◽  
Full Flexion ◽  
Pigmented Villonodular

Background: PVNS is a rare, benign & aggressive disorder arising from either synovial joints or tendon sheaths; it may erode articular structures and bones. We present a case with unique features of PVNS being extra-synovial and by this report we open a gate for more researches in this field. Case Presentation: This case report concerns a 35-year-old female with a history of right knee pain for 6-month duration proceeded by gradual swelling over posterior aspect of the knee, she denies any history of trauma, clinical examination was unremarkable but apart from tenderness over the infrapatellar region with full flexion. MRI shows a heterogenous signal extra-articular and extra-synovial lesion in posterior aspect of the knee suggesting Pigmented Villonodular Synovitis, FNA revealed a hemosiderin-laden macrophages and multinucleated giant cells, Tru-cut biopsy result was suggesting PVNS as synovial cells were seen admixed with hemosiderin-laden macrophages with fibroblastic elements. Through posterior approach; the lesion was surgically excised and histopathological examination confirmed the diagnosis, the lesion was recurrent after 1-year and MRI revealed the same features, the lesion was excised by arthroscopic intervention. Conclusion: We concluded that PVNS cannot be excluded when extra-synovial lesion is assessed, and further researches on this topic will expand our understanding of the etiological and pathological aspects of this tumor.

scholarly journals Localized Pigmented Villonodular Synovitis of the Hip: Sudden-Onset Pain Caused by Torsion of the Tumor Pedicle

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Kiyokazu Fukui ◽  
Ayumi Kaneuji ◽  
Eriko Kinoshita ◽  
Yuhei Numata ◽  
Takayuki Nojima ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Histopathological Examination ◽  
Giant Cells ◽  
Pigmented Villonodular Synovitis ◽  
Sudden Onset ◽  
Resected Specimen ◽  
Villonodular Synovitis ◽  
Surgical Dislocation ◽  
Localized Pigmented Villonodular Synovitis ◽  
Pigmented Villonodular

Pigmented villonodular synovitis is a rare, benign, but potentially locally aggressive disease that should be considered in younger patients who present with monoarticular joint symptoms and pathology. We present the case of a 33-year-old woman with a mass arising from her right hip joint that was examined using a multimodal radiological approach. Because her clinical presentation mimicked that of synovial osteochondromatosis of the hip, surgical dislocation was performed. Histopathological examination of the resected specimen confirmed the diagnosis of localized pigmented villonodular synovitis, with the mass consisting of proliferation of fibrohistiocytic cells, abundant hemosiderin, foamy histiocytes, and occasional giant cells. Because of the presence of tumor necrosis, we hypothesize that torsion of the tumor pedicle was the cause of acute presentation.

scholarly journals Monoarticular synovitis of knee: dealing with the dilemma

SICOT-J ◽  
2020 ◽  
Vol 6 ◽  
pp. 48
Author(s):  
Tarun Goyal ◽  
Souvik Paul ◽  
Arghya Kundu Choudhury ◽  
Tushar Kalonia
Keyword(s):  
Rheumatoid Arthritis ◽  
Histopathological Examination ◽  
Specific Treatment ◽  
Pigmented Villonodular Synovitis ◽  
Functional Improvement ◽  
Villonodular Synovitis ◽  
Duration Of Symptoms ◽  
Large Joint ◽  
Chronic Synovitis ◽  
Pigmented Villonodular

Introduction: Chronic synovitis involving a single large joint remains a diagnostic dilemma. We present 61 cases of chronic synovitis of the knee, followed prospectively for 2 years. The study focuses on the diagnosis, management, and histopathological correlation. Methods: We prospectively studied 61 patients with chronic mono-articular synovitis of the knee joint, between July 2016 and September 2017. All patients underwent plain radiographs, magnetic resonance imaging, and arthroscopic examination with synovial biopsy. Further treatment was based on findings of histopathological examination. Results: The average duration of symptoms was 7.72 ± 4.34 months. The mean age at presentation was 29.93 ± 15.56 years. Results of histopathological examination showed chronic nonspecific inflammation in 28 patients (46%), features suggesting tubercular infection in 19 patients (31%), pigmented villonodular synovitis in seven patients (11.5%), rheumatoid arthritis in three (5%) patients, acute inflammation in three (5%) patients and findings suggestive of synovial chondromatosis in one (1.5%) patient. Treatment was based on histopathological results. Intra-articular injections of methylprednisolone (80 mg depot preparation) were given to all patients with nonspecific synovitis and rheumatoid arthritis. Anti-tubercular treatment was started for patients with tubercular synovitis. Complete arthroscopic/open synovectomy followed by radiotherapy was carried out for patients with pigmented villonodular synovitis. Non-steroidal anti-inflammatory drugs are used for patients with acute on chronic inflammation. All patients had symptomatic relief and functional improvement in further follow-up. Discussion: Histopathological reporting remains the mainstay for diagnosis. The various differentials should always be kept in mind when approaching patients with chronic mono-articular synovitis. Specific treatment can be started once the diagnosis is confirmed.

Pigmented Villonodular Synovitis of the Temporomandibular Joint

1982 ◽  
Vol 90 (5) ◽  
pp. 668-670 ◽  
Author(s):  
Robert R. Rickert ◽  
Myron J. Shapiro
Keyword(s):  
Temporomandibular Joint ◽  
Tendon Sheath ◽  
Giant Cells ◽  
Pigmented Villonodular Synovitis ◽  
Resected Specimen ◽  
Villonodular Synovitis ◽  
Clinical Appearance ◽  
The Family ◽  
Proliferative Lesion ◽  
Pigmented Villonodular

A 39-year-old woman had a large asymptomatic left parotid mass that she had apparently not noticed. The clinical appearance suggested a parotid tumor. Aspirated tissue revealed numerous giant cells, histiocytes, and hemosiderin pigment. At surgical exploration a tumor was found deep to the facial nerve involving the temporomandibular joint, which had a brown-stained roughened synovial membrane. The resected specimen histologically was a proliferative lesion composed of epithelioid histiocytes, spindle cells, and multinucleated giant cells. The appearance was typical of the family of lesions that includes pigmented villonodular synovitis, bursitis, and tenosynovitis (giant cell “tumor” of tendon sheath). In view of the origin from the temporomandibular joint, reinforced by a characteristic radiologic appearance, we interpret this as a case of pigmented villonodular synovitis. This is the fifth case reported from this site.

scholarly journals Intra and extraarticular localized pigmented villonodular synovitis

2021 ◽  
Vol 8 (1) ◽  
pp. 110
Author(s):  
Johney Juneja ◽  
Raghavendra Choubsia ◽  
Ramesh Sen ◽  
A. K. Mehra ◽  
Basant Aggarwal ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Pigmented Villonodular Synovitis ◽  
Villonodular Synovitis ◽  
Tissue Mass ◽  
Limited Mobility ◽  
History Of ◽  
Knee Trauma ◽  
Localized Pigmented Villonodular Synovitis ◽  
Pigmented Villonodular

<p class="abstract">A 28 year old woman had a history of knee trauma and presented with unilateral knee acute swelling and pain symptoms with sudden onset, which was there from last 2 years. She had been treated for seronegative rheumatoid patient for 1 year. Recent expansion of the LPVNS (localized pigmented villonodular synovitis) caused the development of a tender palpable soft tissue mass in the anterolateral aspect of the knee and acute reduced mobility. Preoperative magnetic resonance imaging of the knee revealed the presence of only the soft tissue mass and mild degenerative changes. Open synovectomy was performed successfully to excise the mass. Intraoperatively, macroscopic features of the bright brown inflamed synovium suggested LPVNS, which was confirmed histopathologically. Postoperatively, the symptoms of limited mobility and pain were appreciably relieved. Recurrence was not observed during the clinical follow up at 1, 6 or 18 months after surgery. Here, we reported the unique case of localized pigmented villonodular synovitis of the knee in a misdiagnosed patient with intra and extraarticular lesion, which might be attributed to the history of knee trauma and the focal defect of the lateral patellar retinaculum. Open synovectomy effectively relieved the symptoms of limited mobility and pain and no recurrence was observed prior to 18 months postoperatively. To reduce misdiagnosis, MRI examinations are recommended for all patients suspected of having PVNS, including those who have a history of hyperuricemia.</p>

scholarly journals Arthroscopic Management of Pigmented Villonodular Synovitis of the Hip: A Case Report

2020 ◽  
pp. 1-4
Author(s):  
Ashok S Paul ◽  
Omar El-Omar ◽  
Sanat Shah ◽  
Ashok S Paul
Keyword(s):  
Recent Literature ◽  
Pigmented Villonodular Synovitis ◽  
Open Approach ◽  
Villonodular Synovitis ◽  
Case Presentation ◽  
Arthroscopic Management ◽  
Advantages And Disadvantages ◽  
The Right ◽  
Pigmented Villonodular ◽  
Lower Morbidity

Background: Pigmented villonodular synovitis, particularly of the hip joint, has been historically treated via open synovectomy. However, an arthroscopic approach to management has been trailed successfully in recent years and has demonstrated encouraging outcomes. Case Presentation: We report the case of a 17-year-old man with pigmented villonodular synovitis of the right hip who underwent arthroscopic treatment. He remains well 5 years later with no signs of recurrence. We discuss the advantages and disadvantages of arthroscopically managed pigmented villonodular synovitis as well as the recent literature surrounding this topic. We also explain a technical tip during hip arthroscopy to access these difficult lesions. Conclusion: Arthroscopy can be used for hip pigmented villonodular synovitis treatment. These lesions may also be accessed by extending the hip to 10 degrees and releasing the traction. There is evidence to suggest that arthroscopically managed pigmented villonodular synovitis carries better outcomes and lower morbidity rates compared to an open approach in suitable cases.

Cell characterization of mononuclear and giant cells constituting pigmented villonodular synovitis

2003 ◽  
Vol 34 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Wataru Yoshida ◽  
Miwa Uzuki ◽  
Akira Kurose ◽  
Masaaki Yoshida ◽  
Jun Nishida ◽  
...  
Keyword(s):  
Giant Cells ◽  
Pigmented Villonodular Synovitis ◽  
Villonodular Synovitis ◽  
Cell Characterization ◽  
Pigmented Villonodular

scholarly journals Diffuse type of pigmented villonodular synovitis of knee masquerading as a soft tissue sarcoma

Biomedicine ◽  
2020 ◽  
Vol 40 (3) ◽  
pp. 405-408
Author(s):  
Bhat Shubha P. ◽  
Singh Vartika ◽  
Srinivas Teerthanath ◽  
Shetty Siddharth M. ◽  
Hosapatna Laxminarayana Kishan Prasad ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Histopathological Examination ◽  
Benign Neoplasm ◽  
Pigmented Villonodular Synovitis ◽  
Villonodular Synovitis ◽  
Diffuse Type ◽  
Diagnostic Challenge ◽  
Radiological Investigation ◽  
Pigmented Villonodular

Pigmented villonodular synovitis (PVNS) is a rare benign neoplasm involving the synovial joints and tendon sheaths. It can be classified into localised and diffuse type. The diffuse type of PVNS is larger and very aggressive, clinically mimicking as soft tissue sarcoma. Radiological investigation can aid in knowing the relation of the mass to the joint cavity and invasion of surrounding structures. A biopsy can pose a diagnostic challenge for  pathologists. Surgical excision is the treatment of choice. Histopathological examination is necessary for a definite diagnosis. Keywords: Pigmented villonodular synovitis; diffuse; soft tissue sarcoma; histopathology.

scholarly journals Open synovectomy treatment for intra- and extraarticular localized pigmented villonodular synovitis of the knee: a case report

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Daoliang Xu ◽  
Jianxia Wen ◽  
Shisi Zhang ◽  
Xiaoyun Pan
Keyword(s):  
Pigmented Villonodular Synovitis ◽  
Villonodular Synovitis ◽  
Unique Case ◽  
Tissue Mass ◽  
Limited Mobility ◽  
Open Synovectomy ◽  
History Of ◽  
Knee Trauma ◽  
Localized Pigmented Villonodular Synovitis ◽  
Pigmented Villonodular

Abstract Background Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferative neoplastic process that commonly affects synovial-lined anatomic spaces. The diffuse type (DPVNS) is characterized by invasion of the entire joint synovium, while the localized type (LPVNS) is characterized by a relatively normal synovial appearance. This report describes a unique case of massive intraarticular LPVNS with an extraarticular extension through the lateral patellar retinaculum. No similar cases have been found in the literature. Case presentation A 58-year-old woman had a history of hyperuricemia and knee trauma and presented with unilateral knee acute swelling and pain symptoms with sudden onset. Recent expansion of the LPVNS caused the development of a tender palpable soft tissue mass in the anterolateral aspect of the knee and acute reduced mobility. Preoperative magnetic resonance imaging of the knee revealed the presence of only the soft tissue mass and mild degenerative changes. Open synovectomy was performed successfully to excise the mass. Intraoperatively, macroscopic features of the bright brown inflamed synovium suggested LPVNS, which was confirmed histopathologically. Postoperatively, the symptoms of limited mobility and pain were appreciably relieved. Recurrence was not observed during the clinical follow-up at 1, 6 or 18 months after surgery. Conclusions Here, we report the unique case of localized pigmented villonodular synovitis of the knee in a misdiagnosed patient with intra- and extraarticular lesion, which might be attributed to the history of knee trauma and the focal defect of the lateral patellar retinaculum. Open synovectomy effectively relieved the symptoms of limited mobility and pain and no recurrence was observed prior to 18 months postoperatively. To reduce misdiagnosis, MRI examinations are recommended for all patients suspected of having PVNS, including those who have a history of hyperuricemia.

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